Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Eric A Porsch"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The bacterial genus Kingella includes two pathogenic species, namely Kingella kingae and Kingella negevensis, as well as strictly commensal species. Both K. kingae and K. negevensis secrete a toxin called RtxA that is absent in the commensal
Externí odkaz:
https://doaj.org/article/c2a5d2aa2e954def9d32206c4b073bec
Autor:
Nina R. Montoya, Eric A. Porsch, Vanessa L. Muñoz, Artur Muszyński, Jiri Vlach, David K. Hahn, Parastoo Azadi, Matthew Sherman, Hyojik Yang, Courtney E. Chandler, Robert K. Ernst, Joseph W. St. Geme
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Kingella kingae is a leading cause of bone and joint infections and other invasive diseases in young children. A key K. kingae virulence determinant is a secreted exopolysaccharide that mediates resistance to serum complement and neutrophils
Externí odkaz:
https://doaj.org/article/1ed85223c9a446f9aa4b949b4fbcc49e
Autor:
Eric A. Porsch, Kevin A. Hernandez, Daniel P. Morreale, Nina R. Montoya, Taylor A. Yount, Joseph W. St. Geme
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Kingella kingae is an emerging pediatric pathogen and is increasingly recognized as a leading etiology of septic arthritis, osteomyelitis, and bacteremia and an occasional cause of endocarditis in young children. The pathogenesis of K. kingae disease
Externí odkaz:
https://doaj.org/article/8d30f10bd26d4e6ab86b85b04d8827b6
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010440 (2022)
The gram-negative bacterium Kingella kingae is a leading cause of osteoarticular infections in young children and initiates infection by colonizing the oropharynx. Adherence to respiratory epithelial cells represents an initial step in the process of
Externí odkaz:
https://doaj.org/article/209e7c83bb884bc78c30130c9c1ecc6c
Autor:
Ariadna Fernández-Calvet, Begoña Euba, Celia Gil-Campillo, Arancha Catalan-Moreno, Javier Moleres, Sara Martí, Alexandra Merlos, Jeroen D. Langereis, Francisco García-del Portillo, Lauren O. Bakaletz, Garth D. Ehrlich, Eric A. Porsch, Margarita Menéndez, Joshua C. Mell, Alejandro Toledo-Arana, Junkal Garmendia
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Human-adapted bacterial pathogens have evolved specific mechanisms to colonize their host niche. Phase variation is a contingency strategy to allow adaptation to changing conditions, as phase-variable bacterial loci rapidly and reversibly switch thei
Externí odkaz:
https://doaj.org/article/07720d572d9e49e499e710710932f33f
Autor:
Eric A. Porsch
Publikováno v:
Microorganisms, Vol 10, Iss 5, p 997 (2022)
The emergence of Kingella kingae as an important etiology of pediatric osteoarticular infections over the past three decades has led to significant research efforts focused on understanding the pathogenicity of this fastidious Gram-negative bacterium
Externí odkaz:
https://doaj.org/article/a976cc559521406ab5cf6b655505cb46
Autor:
Joshua M. Maher, Rodrigo E. Mendes, Holly K. Huynh, Eric A. Porsch, Joseph W. St. Geme III, Pablo Yagupsky, John Bradley
Publikováno v:
Pediatric Infectious Disease Journal. 42:206-211
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241511 (2020)
Kingella negevensis is a newly described gram-negative bacterium in the Neisseriaceae family and is closely related to Kingella kingae, an important cause of pediatric osteoarticular infections and other invasive diseases. Like K. kingae, K. negevens
Externí odkaz:
https://doaj.org/article/f97559a3ea694f83b3e5a5638fc26b20
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Bacterial pathogens have evolved strategies that enable them to evade neutrophil-mediated killing. The Gram-negative coccobacillus Kingella kingae is an emerging pediatric pathogen and is increasingly recognized as a common etiological agent
Externí odkaz:
https://doaj.org/article/30f4401359d54c7583d0ee695ebaffd2
Publikováno v:
Infection and Immunity. 91
Kingella kingae is an emerging pathogen that has recently been identified as a leading cause of osteoarticular infections in young children. Colonization with K. kingae is common, with approximately 10% of young children carrying this organism in the