Zobrazeno 1 - 10
of 388
pro vyhledávání: '"Eric A Miska"'
Autor:
Parthena Konstantinidou, Zuzana Loubalova, Franziska Ahrend, Aleksandr Friman, Miguel Vasconcelos Almeida, Axel Poulet, Filip Horvat, Yuejun Wang, Wolfgang Losert, Hernan Lorenzi, Petr Svoboda, Eric A. Miska, Josien C. van Wolfswinkel, Astrid D. Haase
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114777- (2024)
Summary: PIWI-interacting RNAs (piRNAs) play a crucial role in safeguarding genome integrity by silencing mobile genetic elements. From flies to humans, piRNAs originate from long single-stranded precursors encoded by genomic piRNA clusters. How piRN
Externí odkaz:
https://doaj.org/article/d5ee216aeb984bc49d474c711d1860ea
Autor:
Amy K. Stainthorp, Chi-Chuan Lin, Dapeng Wang, Ragini Medhi, Zamal Ahmed, Kin Man Suen, Eric A. Miska, Adrian Whitehouse, John E. Ladbury
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Protein interactions with the microRNA (miRNA)-mediated gene silencing protein Argonaute 2 (AGO2) control miRNA expression. miRNA biogenesis starts with the production of precursor transcripts and culminates with the loading of mature miRNA
Externí odkaz:
https://doaj.org/article/756e1110262445a7a318ca1ffe0841ca
Autor:
Iliana Bista, Jonathan M. D. Wood, Thomas Desvignes, Shane A. McCarthy, Michael Matschiner, Zemin Ning, Alan Tracey, James Torrance, Ying Sims, William Chow, Michelle Smith, Karen Oliver, Leanne Haggerty, Walter Salzburger, John H. Postlethwait, Kerstin Howe, Melody S. Clark, H. William Detrich, C.-H. Christina Cheng, Eric A. Miska, Richard Durbin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Numerous novel adaptations characterise the radiation of notothenioids, the dominant fish group in the freezing seas of the Southern Ocean. To improve understanding of the evolution of this iconic fish group, here we generate and analyse new
Externí odkaz:
https://doaj.org/article/a84ba1265012436ab251e62f2ecd1c47
Autor:
David J Jordan, Eric A Miska
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 11, Pp n/a-n/a (2023)
Abstract How do the same mechanisms that faithfully regenerate complex developmental programmes in spite of environmental and genetic perturbations also allow responsiveness to environmental signals, adaptation and genetic evolution? Using the nemato
Externí odkaz:
https://doaj.org/article/2baf0091944045bea8fb0addf75d01cb
Autor:
Bethan F Manley, Jaruwatana S Lotharukpong, Josué Barrera-Redondo, Theo Llewellyn, Gokalp Yildirir, Jana Sperschneider, Nicolas Corradi, Uta Paszkowski, Eric A Miska, Alexandra Dallaire
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 6 (2023)
AbstractThe root systems of most plant species are aided by the soil-foraging capacities of symbiotic arbuscular mycorrhizal (AM) fungi of the Glomeromycotina subphylum. Despite recent advances in our knowledge of the ecology and molecular biology of
Externí odkaz:
https://doaj.org/article/51d4360271de49aca54218adfd82a600
Autor:
Ilias Georgakopoulos-Soares, Guillermo E. Parada, Hei Yuen Wong, Ragini Medhi, Giulia Furlan, Roberto Munita, Eric A. Miska, Chun Kit Kwok, Martin Hemberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here the authors shows that G-quadruplexes, non-canonical DNA/RNA structures, can have a direct impact on alternative splicing and that binding of splicing regulators is affected by their presence.
Externí odkaz:
https://doaj.org/article/1779cd252e244da5bbde00ae5b70b88c
Autor:
Grégoire Vernaz, Milan Malinsky, Hannes Svardal, Mingliu Du, Alexandra M. Tyers, M. Emília Santos, Richard Durbin, Martin J. Genner, George F. Turner, Eric A. Miska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The Lake Malawi cichlid fishes are an example of extreme vertebrate radiation; however, there is very little sequence divergence among the species. Here the authors present a comparative genome-wide methylome study to suggest DNA methylation played a
Externí odkaz:
https://doaj.org/article/1a787f2ae63e44f3b0f679f4ecaa9219
Autor:
IC Navarro, Dalila Bensaddek, Kin Man Suen, Angus Lamond, Arun Tanpure, Eric A Miska, Shankar Balasubramanian
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: Methylation of carbon-5 of cytosines (m5C) is a conserved post-transcriptional nucleotide modification of RNA with widespread distribution across organisms. It can be further modified to yield 5-hydroxymethylcytidine (hm5C), 5-formylcytid
Externí odkaz:
https://doaj.org/article/7be7f37ee54c49e68426dbf39db16b70
Autor:
Guillermo E. Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo J. R. Fernandes, Veronika R. Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A. Miska, Martin Hemberg
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background Microexons, exons that are ≤ 30 nucleotides, are a highly conserved and dynamically regulated set of cassette exons. They have key roles in nervous system development and function, as evidenced by recent results demonstrating th
Externí odkaz:
https://doaj.org/article/0d157abfd9a941beba50e1568885e813
Autor:
Shraddha Puntambekar, Rachel Newhouse, Jaime San Miguel Navas, Ruchi Chauhan, Grégoire Vernaz, Thomas Willis, Matthew T. Wayland, Yagnesh Umrania, Eric A. Miska, Sudhakaran Prabakaran
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Novel open reading frames (nORFs) with coding potential may arise from noncoding DNA. Not much is known about their emergence, functional role, fixation in a population or contribution to adaptive radiation. Cichlids fishes exhibit extensive
Externí odkaz:
https://doaj.org/article/d7a75993196c48729509b1ea6dea1a13