Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Eric A Engleman"'
Autor:
Gregory G Grecco, Briana E Mork, Jui-Yen Huang, Corinne E Metzger, David L Haggerty, Kaitlin C Reeves, Yong Gao, Hunter Hoffman, Simon N Katner, Andrea R Masters, Cameron W Morris, Erin A Newell, Eric A Engleman, Anthony J Baucum, Jiuen Kim, Bryan K Yamamoto, Matthew R Allen, Yu-Chien Wu, Hui-Chen Lu, Patrick L Sheets, Brady K Atwood
Publikováno v:
eLife, Vol 10 (2021)
Despite the rising prevalence of methadone treatment in pregnant women with opioid use disorder, the effects of methadone on neurobehavioral development remain unclear. We developed a translational mouse model of prenatal methadone exposure (PME) tha
Externí odkaz:
https://doaj.org/article/5a76cf5be8ef4e9aa4a2a863c7ea3745
Autor:
Thatiane De Oliveira Sergio, Rebecca Jane Smith, Sarah E. Wean, Eric A. Engleman, Frederic W. Hopf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Binge drinking (BD) contributes strongly to the harms of alcohol use disorder. Most rodent models do not result in binge-level blood alcohol concentrations (BACs), and to better understand individual and sex differences in neurobiological me
Externí odkaz:
https://doaj.org/article/7f2963176f284f80989f313914cb5bc5
Autor:
Sheketha R. Hauser, Robert A. Waeiss, Gerald A. Deehan, Eric A. Engleman, Richard L. Bell, Zachary A. Rodd
Publikováno v:
Advances in Drug and Alcohol Research, Vol 3 (2023)
Adolescence through young adulthood is a unique period of neuronal development and maturation. Numerous agents can alter this process, resulting in long-term neurological and biological consequences. In the clinical literature, it is frequently repor
Externí odkaz:
https://doaj.org/article/6a9c419e5c804ae8a686806fcdda6302
Autor:
Zachary A. Rodd, H. Scott Swartzwelder, R. Aaron Waeiss, Serhii O. Soloviov, Debomoy K. Lahiri, Eric A. Engleman, William A. Truitt, Richard L. Bell, Sheketha R. Hauser
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
Rationale and Objectives: Ethanol acts directly on the α7 Nicotinic acetylcholine receptor (α7). Adolescent-binge alcohol exposure (ABAE) produces deleterious consequences during adulthood, and data indicate that the α7 receptor regulates these da
Externí odkaz:
https://doaj.org/article/5cc9504e8a344830b1a157ff04718db6
Autor:
Eric A. Engleman, Kevin B. Steagall, Kristin E. Bredhold, Michaela Breach, Hannah L. Kline, Richard L. Bell, Simon N. Katner, Bethany S. Neal-Beliveau
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The nematode Caenorhabditis elegans (C. elegans) is a popular invertebrate model organism to study neurobiological disease states. This is due in part to the intricate mapping of all neurons and synapses of the entire animal, the wide availability of
Externí odkaz:
https://doaj.org/article/60925968bb894fb5a9073e1a0f2657c0
Autor:
Simon N. Katner, Alena M. Sentir, Kevin B. Steagall, Zheng-Ming Ding, Leah Wetherill, Frederic W. Hopf, Eric A. Engleman
Publikováno v:
Brain Sciences; Volume 12; Issue 8; Pages: 1042
With the substantial social and medical burden of addiction, there is considerable interest in understanding risk factors that increase the development of addiction. A key feature of alcohol use disorder (AUD) is compulsive alcohol (EtOH) drinking, w
Autor:
Sheketha R. Hauser, Gerald A. Deehan, Christopher P. Knight, Robert A. Waeiss, Eric A. Engleman, Zheng-Ming Ding, Phillip L. Johnson, William J. McBride, William A. Truitt, Zachary A. Rodd
Publikováno v:
Drug and Alcohol Dependence. 246:109858
Autor:
Zachary A. Rodd, Eric A. Engleman, William A. Truitt, Andrew R. Burke, Andrei I. Molosh, Richard L. Bell, Sheketha R. Hauser
Publikováno v:
Neuroscience. 491
The chemogenetic procedure DREADD (designer receptor exclusively activated by designer drugs) is an inventive way to selectively affect g-coupled protein receptors. In theory, DREADD receptors are only activated by administering inert compounds, prim
Autor:
Richard L. Bell, Patrick J. Mulholland, Zachary A. Rodd, R. Aaron Waeiss, Sheketha R. Hauser, William A. Truitt, Eric A. Engleman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11733, p 11733 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences
Volume 22
Issue 21
A consistent preclinical finding is that exposure to alcohol during adolescence produces a persistent hyperdopaminergic state during adulthood. The current experiments determine that effects of Adolescent Intermittent Ethanol (AIE) on the adult neuro
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Alcoholism is a serious public health concern that is characterized by the development of tolerance to alcohol’s effects, increased consumption, loss of control over drinking and the development of physical dependence. This cycle is often times pun
Externí odkaz:
https://doaj.org/article/f57c26ae90de4279b3a4a6267b3257a7