Zobrazeno 1 - 10
of 288
pro vyhledávání: '"Eric F. Johnson"'
Autor:
Junichiro Yuda, Christine Will, Darren C. Phillips, Linu Abraham, Cory Alvey, Abraham Avigdor, Wayne Buck, Lauren Besenhofer, Erwin Boghaert, Dong Cheng, Dan Cojocari, Kelly Doyle, T. Matthew Hansen, Kevin Huang, Eric F. Johnson, Andrew S. Judd, Russell A. Judge, John C. Kalvass, Aaron Kunzer, Lloyd T. Lam, Rachel Li, Ruth L. Martin, Anthony Mastracchio, Mike Mitten, Adam Petrich, Jin Wang, James E. Ward, Haichao Zhang, Xilu Wang, Johannes E. Wolff, Katherine M. Bell-McGuinn, Andrew J. Souers
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Abstract Background MCL-1 is a prosurvival B-cell lymphoma 2 family protein that plays a critical role in tumor maintenance and survival and can act as a resistance factor to multiple anticancer therapies. Herein, we describe the generation and chara
Externí odkaz:
https://doaj.org/article/a09a2953c50e4da8ad9915dfa149ffac
Publikováno v:
Drug Metabolism and Disposition. 51:105-110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::667f8c560c22e8e24706f63516cd32bf
https://doi.org/10.1124/dmd.122.000986
https://doi.org/10.1124/dmd.122.000986
Autor:
David Maag, Eric F. Johnson, Donald J. Osterling, DeAnne F. Stolarik, Amanda M. Olson, Wenqing Gao, Julie L. Wilsbacher, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Larry R. Solomon, Luis E. Rodriguez, Yan Shi, Todd A. Hopkins
Supplementary figures S1-S6, tables 1 and 2. Table S1. Body weight loss and health observations in HeyA8 xenograft tumor-bearing mice treated with PARP inhibitors or TMZ alone or in combination. Table S2. Summary of PK parameters in HeyA8 xenograft t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcfa08a35c000c13a490792d1596a75
https://doi.org/10.1158/1541-7786.22514481.v1
https://doi.org/10.1158/1541-7786.22514481.v1
Autor:
David Maag, Julie L. Wilsbacher, Eric F. Johnson, Amanda M. Olson, Yan Shi, Mikkel A. Algire, Vivek C. Abraham, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Paul A. Ellis, William B. Ainsworth, Todd A. Hopkins
Association of PARP1 and H2A.X detected by Proximity Ligation Assay (PLA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d490333306545aace2682f34c3fb2b1
https://doi.org/10.1158/1541-7786.22514785.v1
https://doi.org/10.1158/1541-7786.22514785.v1
Autor:
David Maag, Julie L. Wilsbacher, Eric F. Johnson, Amanda M. Olson, Yan Shi, Mikkel A. Algire, Vivek C. Abraham, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Paul A. Ellis, William B. Ainsworth, Todd A. Hopkins
Association of PARP1 and other histone proteins detected by Proximity Ligation Assay (PLA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a73200cd0e0b2826cfb29f9594a526
https://doi.org/10.1158/1541-7786.22514782
https://doi.org/10.1158/1541-7786.22514782
Autor:
David Maag, Julie L. Wilsbacher, Eric F. Johnson, Amanda M. Olson, Yan Shi, Mikkel A. Algire, Vivek C. Abraham, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Paul A. Ellis, William B. Ainsworth, Todd A. Hopkins
IC50 values of PARPi vs BM-CFU and BM-PAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a64aa11e2b2967e2f843fb56859904
https://doi.org/10.1158/1541-7786.22514773
https://doi.org/10.1158/1541-7786.22514773
Autor:
David Maag, Julie L. Wilsbacher, Eric F. Johnson, Amanda M. Olson, Yan Shi, Mikkel A. Algire, Vivek C. Abraham, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Paul A. Ellis, William B. Ainsworth, Todd A. Hopkins
Clinical RP2D concentrations for PARP inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4316ce74d1ccc2bcb5ea88f60741cf
https://doi.org/10.1158/1541-7786.22514776.v1
https://doi.org/10.1158/1541-7786.22514776.v1
Autor:
David Maag, Julie L. Wilsbacher, Eric F. Johnson, Amanda M. Olson, Yan Shi, Mikkel A. Algire, Vivek C. Abraham, Sanjay C. Panchal, Enrico L. DiGiammarino, Cherrie K. Donawho, Paul A. Ellis, William B. Ainsworth, Todd A. Hopkins
Bone Marrow IC50s broken into cell type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e498c80f13b9c6f3eef5213b00c9a4
https://doi.org/10.1158/1541-7786.22514770
https://doi.org/10.1158/1541-7786.22514770
Autor:
Alexander R. Shoemaker, Eric F. Johnson, Joel Leverson, Yan Luo, Vincent L. Giranda, Saul Rosenberg, Thomas Penning, Gui-dong Zhu, Joann Palma, Loren Lasko, Lisa Roberts, Thomas McGonigal, Gang Wang, Dimitri Semizarov, Yan Shi, Mark Anderson, Edward K. Han, Xuesong Liu
Supplementary Data from Acquired Resistance to Combination Treatment with Temozolomide and ABT-888 Is Mediated by Both Base Excision Repair and Homologous Recombination DNA Repair Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7adbcf3cdc98e10819a2cee5137aaf0
https://doi.org/10.1158/1541-7786.22521748
https://doi.org/10.1158/1541-7786.22521748
Publikováno v:
Access Microbiology. 5
Methanocaldococcus jannaschii (Mj), a hyperthermophilic and evolutionarily deeply rooted methanogenic archaeon from a deep-sea hydrothermal vent, produces F420-dependent sulphite reductase (Fsr) in response to exposure to sulphite. This enzyme allows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c115cb08d3ee0201535e0e069a5dfe
https://doi.org/10.1099/acmi.0.000482.v3
https://doi.org/10.1099/acmi.0.000482.v3