Zobrazeno 1 - 10
of 890
pro vyhledávání: '"Eric, Van Cutsem"'
Autor:
Elena Elez, Antonio Cubillo, Pilar Garcia Alfonso, Mark R. Middleton, Ian Chau, Baha Alkuzweny, Ann Alcasid, Xiaosong Zhang, Eric Van Cutsem
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background In patients with previously treated RAS-mutated microsatellite-stable (MSS) metastatic colorectal cancer (mCRC), a multicenter open-label phase 1b/2 trial was conducted to define the safety and efficacy of the MEK1/MEK2 inhibitor
Externí odkaz:
https://doaj.org/article/df5ecc4526e845d49481ee6aa799d831
Autor:
Sara Lonardi, Eric Van Cutsem, Pilar Garcia-Alfonso, Mark Wong, Fabio Gelsomino, Bassel El-rayes, Michael J Overman, Andrew G Hill, Ming Lei, Massimo Aglietta, Maria Luisa Limon Miron, Gregory Leonard, Antonio Cubillo Gracian, Stephen M McCraith, Beilei He
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Programmed death-1 (PD-1) inhibitors, including nivolumab, have demonstrated long-term survival benefit in previously treated patients with microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer
Externí odkaz:
https://doaj.org/article/8837ecde8e2f4b09ba632cfba21417dd
Autor:
Thuy Ngan Tran, Joanna Bouchat, Marc Peeters, Bea Berghmans, Eric Van Cutsem, Guido Van Hal, Koen Van Herck, Sarah Hoeck
Publikováno v:
Gastrointestinal Disorders, Vol 6, Iss 1, Pp 26-48 (2024)
Monitoring complications of colonoscopies after a positive faecal immunochemical test (FIT-colonoscopies) is crucial in FIT-based colorectal cancer (CRC) screening. We investigated the occurrence of bleeding and perforation post FIT-colonoscopies (20
Externí odkaz:
https://doaj.org/article/37b93e946b1846488ee0b4440d923440
Autor:
Sarah Cappuyns, Gino Philips, Vincent Vandecaveye, Bram Boeckx, Rogier Schepers, Thomas Van Brussel, Ingrid Arijs, Aurelie Mechels, Ayse Bassez, Francesca Lodi, Joris Jaekers, Halit Topal, Baki Topal, Orian Bricard, Junbin Qian, Eric Van Cutsem, Chris Verslype, Diether Lambrechts, Jeroen Dekervel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The combination of atezolizumab plus bevacizumab (atezo/bev) has dramatically changed the treatment landscape of advanced HCC (aHCC), achieving durable responses in some patients. Using single-cell transcriptomics, we characterize the intra-
Externí odkaz:
https://doaj.org/article/db4b12030ddd4fd095ec4bcc29c92ddb
Autor:
Lennert Boeckxstaens, Elin Pauwels, Vincent Vandecaveye, Wies Deckers, Frederik Cleeren, Jeroen Dekervel, Timon Vandamme, Kim Serdons, Michel Koole, Guy Bormans, Annouschka Laenen, Paul M. Clement, Karen Geboes, Eric Van Cutsem, Kristiaan Nackaerts, Sigrid Stroobants, Chris Verslype, Koen Van Laere, Christophe M. Deroose
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Background Fluorine-18-labeled SSAs have the potential to become the next-generation tracer in SSTR-imaging in neuroendocrine tumor (NET) patients given their logistical advantages over the current gold standard gallium-68-labeled SSAs. In p
Externí odkaz:
https://doaj.org/article/488c4094d49d4d999e7ac7b3db986476
Autor:
Jos van Pelt, Bob Meeusen, Rita Derua, Liesbeth Guffens, Eric Van Cutsem, Veerle Janssens, Chris Verslype
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) has a low survival, its incidence is rising and little therapeutic improvements are expected in the near future. It has been observed that Epithelial-to-Mesenchymal transition (EMT) contribu
Externí odkaz:
https://doaj.org/article/62e9bee916614108bb722b3a189cf40e
Autor:
Géraldine Lens, Niloefar Ahmadi Bidakhvidi, Vincent Vandecaveye, Steven Grauwels, Annouschka Laenen, Wies Deckers, Ronald Peeters, Raphaëla C. Dresen, Jeroen Dekervel, Chris Verslype, Kristiaan Nackaerts, Paul M. Clement, Eric Van Cutsem, Michel Koole, Karolien Goffin, Koen Van Laere, Christophe M. Deroose
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Somatostatin receptor (SSTR) positron emission tomography (PET) is a cornerstone of neuroendocrine tumor (NET) management. Hybrid PET/magnetic resonance imaging (MRI) is now available for NET-imaging, next to PET/computed tomography (CT).
Externí odkaz:
https://doaj.org/article/cc931bab05e442bcb26ced2b04448c47
Autor:
Viktor Proesmans, Tom Vandaele, Jan Van Slambrouck, Albert Wolthuis, André D´Hoore, Jeroen Dekervel, Eric Van Cutsem, Raphaëla Dresen, Gert De Hertogh, Karlien Degezelle, Dirk Van Raemdonck, Philippe Nafteux, Laurens J. Ceulemans
Publikováno v:
International Journal of Hyperthermia, Vol 39, Iss 1, Pp 1153-1157 (2022)
Aim: Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available.Methods: We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemina
Externí odkaz:
https://doaj.org/article/d3856c70e6c1488bacd87971da5dc8e4
Autor:
Philippe P. Bulens, Lien Smets, Annelies Debucquoy, Ines Joye, André D'Hoore, Albert Wolthuis, Lynn Debrun, Jeroen Dekervel, Eric Van Cutsem, Raphaëla Dresen, Vincent Vandecaveye, Christophe M. Deroose, Xavier Sagaert, Karin Haustermans
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 36, Iss , Pp 113-120 (2022)
Purpose: To report on organ preservation following chemoradiotherapy (CRT) in a prospective cohort of locally advanced rectal cancer patients. Methods and materials: Fifty-two patients received CRT. MRI and 18F-FDG-PET/CT were performed prior to CRT.
Externí odkaz:
https://doaj.org/article/3d23d26a785e43fd8a7b86b44d032a7e
Autor:
Tanios Bekaii-Saab, Takuji Okusaka, David Goldstein, Do-Youn Oh, Makoto Ueno, Tatsuya Ioka, Weijia Fang, Eric C. Anderson, Marcus S. Noel, Michele Reni, Hye Jin Choi, Jonathan S. Goldberg, Sang Cheul Oh, Chung-Pin Li, Josep Tabernero, Jian Li, Emma Foos, Cindy Oh, Eric Van Cutsem
Publikováno v:
EClinicalMedicine, Vol 58, Iss , Pp 101897- (2023)
Summary: Background: Compared with normal cells, tumour cells contain elevated levels of reactive oxygen species (ROS). Increased levels of the antioxidant protein NAD(P)H:quinone oxidoreductase 1 (NQO1) and phosphorylated signal transducer and activ
Externí odkaz:
https://doaj.org/article/5dbeea00320a4570827b5add5de5eb9c