Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Eric, Rynes"'
Autor:
Kyle T. Siebenthall, Chris P. Miller, Jeff D. Vierstra, Julie Mathieu, Maria Tretiakova, Alex Reynolds, Richard Sandstrom, Eric Rynes, Eric Haugen, Audra Johnson, Jemma Nelson, Daniel Bates, Morgan Diegel, Douglass Dunn, Mark Frerker, Michael Buckley, Rajinder Kaul, Ying Zheng, Jonathan Himmelfarb, Hannele Ruohola-Baker, Shreeram Akilesh
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 427-442 (2019)
Background: Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transc
Externí odkaz:
https://doaj.org/article/829eb39cb4bc4574ad67b01c5d08b888
Autor:
Benjamin C. Hitz, Jin-Wook Lee, Otto Jolanki, Meenakshi S. Kagda, Keenan Graham, Paul Sud, Idan Gabdank, J. Seth Strattan, Cricket A. Sloan, Timothy Dreszer, Laurence D. Rowe, Nikhil R. Podduturi, Venkat S. Malladi, Esther T. Chan, Jean M. Davidson, Marcus Ho, Stuart Miyasato, Matt Simison, Forrest Tanaka, Yunhai Luo, Ian Whaling, Eurie L. Hong, Brian T. Lee, Richard Sandstrom, Eric Rynes, Jemma Nelson, Andrew Nishida, Alyssa Ingersoll, Michael Buckley, Mark Frerker, Daniel S Kim, Nathan Boley, Diane Trout, Alex Dobin, Sorena Rahmanian, Dana Wyman, Gabriela Balderrama-Gutierrez, Fairlie Reese, Neva C. Durand, Olga Dudchenko, David Weisz, Suhas S. P. Rao, Alyssa Blackburn, Dimos Gkountaroulis, Mahdi Sadr, Moshe Olshansky, Yossi Eliaz, Dat Nguyen, Ivan Bochkov, Muhammad Saad Shamim, Ragini Mahajan, Erez Aiden, Tom Gingeras, Simon Heath, Martin Hirst, W. James Kent, Anshul Kundaje, Ali Mortazavi, Barbara Wold, J. Michael Cherry
The Encyclopedia of DNA elements (ENCODE) project is a collaborative effort to create a comprehensive catalog of functional elements in the human genome. The current database comprises more than 19000 functional genomics experiments across more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ede3b75e1612917e82c16d5ca40cfb
https://doi.org/10.1101/2023.04.04.535623
https://doi.org/10.1101/2023.04.04.535623
Autor:
John A. Stamatoyannopoulos, Mark Frerker, Kristen Lee, Eric Rynes, Douglas Dunn, Michael Buckley, Wouter Meuleman, Fidencio Neri, Athanasios Teodosiadis, Daniel Bates, J. K. Nelson, Alexander L. Muratov, Alex Reynolds, Eric Haugen, Richard Sandstrom, Rajinder Kaul, Morgan Diegel, Jeff Vierstra, Audra K. Johnson, Jessica Halow
Publikováno v:
Nature
DNase I hypersensitive sites (DHSs) are generic markers of regulatory DNA1–5 and contain genetic variations associated with diseases and phenotypic traits6–8. We created high-resolution maps of DHSs from 733 human biosamples encompassing 438 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1968922592eede0146cfe7d06737462
https://doi.org/10.1038/s41586-020-2559-3
https://doi.org/10.1038/s41586-020-2559-3
Autor:
Daniel Bates, Michael Buckley, Mark Frerker, Morgan Diegel, Rajinder Kaul, Eric Rynes, Audra K. Johnson, Alex Reynolds, Eric Haugen, J. K. Nelson, John A. Stamatoyannopoulos, Jessica Halow, Kristen Lee, Fidencio Neri, John Lazar, Douglas Dunn, Wouter Meuleman, Richard Sandstrom, Jeff Vierstra
Publikováno v:
Nature
Combinatorial binding of transcription factors to regulatory DNA underpins gene regulation in all organisms. Genetic variation in regulatory regions has been connected with diseases and diverse phenotypic traits1, but it remains challenging to distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c809e4013d65f8beed3d156b8885aed8
https://doi.org/10.1038/s41586-020-2528-x
https://doi.org/10.1038/s41586-020-2528-x
Autor:
Katharina Brandstetter, Tilo Zülske, Tobias Ragoczy, David Hörl, Miguel Guirao-Ortiz, Clemens Steinek, Toby Barnes, Gabriela Stumberger, Jonathan Schwach, Eric Haugen, Eric Rynes, Philipp Korber, John A. Stamatoyannopoulos, Heinrich Leonhardt, Gero Wedemann, Hartmann Harz
Publikováno v:
Biophysical journal. 121(6)
Methodological advances in conformation capture techniques have fundamentally changed our understanding of chromatin architecture. However, the nanoscale organization of chromatin and its cell-to-cell variance are less studied. Analyzing genome-wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f4665b73dd294e5248594625a018ae
https://pubmed.ncbi.nlm.nih.gov/35150617
https://pubmed.ncbi.nlm.nih.gov/35150617
Autor:
Julie Mathieu, Daniel Bates, Kyle Siebenthall, Maria S. Tretiakova, Hannele Ruohola-Baker, Douglas Dunn, Eric Haugen, Jeff Vierstra, Alex Reynolds, Audra K. Johnson, J. K. Nelson, Michael Buckley, Eric Rynes, Yingye Zheng, Rajinder Kaul, Mark Frerker, Richard Sandstrom, Jonathan Himmelfarb, Chris P. Miller, Morgan Diegel, Shreeram Akilesh
Publikováno v:
EBioMedicine
Background Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8823bb11242f11e78d0eda982cf671b5
https://doi.org/10.1016/j.ebiom.2019.01.063
https://doi.org/10.1016/j.ebiom.2019.01.063
Autor:
David Hoerl, John A. Stamatoyannopoulos, Wedemann G, Katharina Brandstetter, Eric Haugen, Eric Rynes, Zuelske T, Ragoczy T, Hartmann Harz, Heinrich Leonhardt
Methodological advances in conformation capture techniques have fundamentally changed our understanding of chromatin architecture. However, the nanoscale organization of chromatin and its cell-to-cell variance are less studied. By using a combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b7c8dc8b3e570ade02565e8e77d844
https://doi.org/10.1101/2021.05.27.445943
https://doi.org/10.1101/2021.05.27.445943
Autor:
Maia M Chan, Jason M Wooden, Mark Tsang, Diana M Gilligan, Dinesh K Hirenallur-S, Greg L Finney, Eric Rynes, Michael Maccoss, Julita A Ramirez, Heon Park, Brian M Iritani
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54902 (2013)
Hematopoietic protein-1 (Hem-1) is a hematopoietic cell specific member of the WAVE (Wiskott-Aldrich syndrome verprolin-homologous protein) complex, which regulates filamentous actin (F-actin) polymerization in many cell types including immune cells.
Externí odkaz:
https://doaj.org/article/3a3f8926de9342c888d922f1f26fd247
Autor:
Richard Sandstrom, John Lazar, Sean Ibarrientos, Tim R. Mercer, Mark Groudine, John A. Stamatoyannopoulos, Douglas Dunn, Fidencio Neri, Ida M Washington, Eric Haugen, Eric Rynes, Charles E. Breeze, M. A. Bender, Kristen Lee, Morgan Diegel, Rajinder Kaul, Daniel Bates, Alex Reynolds, Jessica Halow, Andres Castillo, Wouter Meuleman
Early mammalian development is orchestrated by genome-encoded regulatory elements populated by a changing complement of regulatory factors, creating a dynamic chromatin landscape. To define the spatiotemporal organization of regulatory DNA landscapes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a010bd5f0d50c8049b301b0cdc04b96f
https://doi.org/10.1101/2020.06.26.172718
https://doi.org/10.1101/2020.06.26.172718
Autor:
Wouter Meuleman, Eric Rynes, Alex Reynolds, Morgan Diegel, Rajinder Kaul, Jeff Vierstra, J. K. Nelson, Douglas Dunn, Jessica Halow, Kristen Lee, Daniel Bates, John A. Stamatoyannopoulos, Audra K. Johnson, Fidencio Neri, Richard Sandstrom, John Lazar, Mark Frerker, Michael Buckley, Eric Haugen
Combinatorial binding of transcription factors to regulatory DNA underpins gene regulation in all organisms. Genetic variation in regulatory regions has been connected with diseases and diverse phenotypic traits1, yet it remains challenging to distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01bbd6941deac7bf95f6f912f255e75