Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Eric, O'Neill"'
Autor:
Mathias Tesson, Katrina Stevenson, Saadia A. Karim, Colin Nixon, Anthony J. Chalmers, Owen J. Sansom, Eric O'Neill, Keaton Jones, Jennifer P. Morton
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/811eecd6813e422088dd8c4cda49dc78
Autor:
David Eric O'Neill, MD, Bhavani Gannavarapu, MD, Brian Hrycushko, PhD, Michael Folkert, MD, PhD, Robert Timmerman, MD, Alexandra Callan, MD
Publikováno v:
OTA International, Vol 6, Iss 2, p e267 (2023)
Abstract. Case:. A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail. Conclusions:. IMBT + intramedullary nail is a new tech
Externí odkaz:
https://doaj.org/article/e2c30df5a85942318210e92509d5aa69
Publikováno v:
Current Oncology, Vol 29, Iss 4, Pp 2516-2529 (2022)
Surgical resection remains the only curative treatment strategy for Pancreatic Ductal Adenocarcinoma (PDAC). A proportion of patients succumb to early disease recurrence post-operatively despite receiving adjuvant chemotherapy. The ability to identif
Externí odkaz:
https://doaj.org/article/7784b4f3a6fc440ca73e4c24d9cbf7b5
Autor:
Edward C Ottley, Robert Pell, Benedict Brazier, Julianne Hollidge, Christiana Kartsonaki, Lisa Browning, Eric O'Neill, Anne E Kiltie
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 6, Iss 4, Pp 238-251 (2020)
Abstract Approximately 75% of bladder cancers are non‐muscle invasive (NMIBC). Of these, up to 53% of cases progress to life‐threatening muscle‐invasive bladder cancer (MIBC). Patients with high‐grade stage T1 (HGT1) NMIBC frequently undergo
Externí odkaz:
https://doaj.org/article/63751b5357d0404a90b79fbc7bbc3d86
Autor:
Victoria Y. Strauss, Rachel Shaw, Pradeep S. Virdee, Christopher N. Hurt, Elizabeth Ward, Bethan Tranter, Neel Patel, John Bridgewater, Philip Parsons, Ganesh Radhakrishna, Eric O’Neill, David Sebag-Montefiore, Maria Hawkins, Pippa G. Corrie, Timothy Maughan, Somnath Mukherjee
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Induction chemotherapy followed by chemoradiation is a treatment option for patients with locally advanced pancreatic cancer (LAPC). However, overall survival is comparable to chemotherapy alone and local progression occurs in nea
Externí odkaz:
https://doaj.org/article/e5a8e148f1a2441296f4f252ecbfeb35
Autor:
Eirini-Stavroula Komseli, Ioannis S. Pateras, Thorbjørn Krejsgaard, Konrad Stawiski, Sophia V. Rizou, Alexander Polyzos, Fani-Marlen Roumelioti, Maria Chiourea, Ioanna Mourkioti, Eleni Paparouna, Christos P. Zampetidis, Sentiljana Gumeni, Ioannis P. Trougakos, Dafni-Eleftheria Pefani, Eric O’Neill, Sarantis Gagos, Aristides G. Eliopoulos, Wojciech Fendler, Dipanjan Chowdhury, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/11f7dd1fa5de402780e7699c1f5acd06
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths worldwide, but has a 5-year survival rate of only 7% primarily due to late diagnosis and ineffective therapies. To treat or even prevent PDAC, it is vital tha
Externí odkaz:
https://doaj.org/article/9288a2513ca94179b6313cfbdf3b61c6
Autor:
Angelos Papaspyropoulos, Leanne Bradley, Asmita Thapa, Chuen Yan Leung, Konstantinos Toskas, Delia Koennig, Dafni-Eleftheria Pefani, Cinzia Raso, Claudia Grou, Garth Hamilton, Nikola Vlahov, Anna Grawenda, Syed Haider, Jagat Chauhan, Ludovico Buti, Alexander Kanapin, Xin Lu, Francesca Buffa, Grigory Dianov, Alex von Kriegsheim, David Matallanas, Anastasia Samsonova, Magdalena Zernicka-Goetz, Eric O’Neill
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
In development, the switch from pluripotency to differentiation is important but it is often unclear how it is regulated. Here, the authors show that the tumour suppressor RASSF1A mediates this switch by promoting YAP-p73 transcription, which in turn
Externí odkaz:
https://doaj.org/article/851da86c94cb4859a74e3f6c31088f3a
Autor:
Eirini-Stavroula Komseli, Ioannis S. Pateras, Thorbjørn Krejsgaard, Konrad Stawiski, Sophia V. Rizou, Alexander Polyzos, Fani-Marlen Roumelioti, Maria Chiourea, Ioanna Mourkioti, Eleni Paparouna, Christos P. Zampetidis, Sentiljana Gumeni, Ioannis P. Trougakos, Dafni-Eleftheria Pefani, Eric O’Neill, Sarantis Gagos, Aristides G. Eliopoulos, Wojciech Fendler, Dipanjan Chowdhury, Jiri Bartek, Vassilis G. Gorgoulis
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-22 (2018)
Abstract Background Senescence is a fundamental biological process implicated in various pathologies, including cancer. Regarding carcinogenesis, senescence signifies, at least in its initial phases, an anti-tumor response that needs to be circumvent
Externí odkaz:
https://doaj.org/article/81dbe18ab5e9469282c85c4909c60800
Autor:
Luana C. Soares, Osama Al-Dalahmah, James Hillis, Christopher C. Young, Isaiah Asbed, Masanori Sakaguchi, Eric O’Neill, Francis G. Szele
Publikováno v:
Cells, Vol 10, Iss 11, p 3047 (2021)
Galectin-3 (Gal-3) is an evolutionarily conserved and multifunctional protein that drives inflammation in disease. Gal-3’s role in the central nervous system has been less studied than in the immune system. However, recent studies show it exacerbat
Externí odkaz:
https://doaj.org/article/e15b078cf39b435ea88580a4252dd451