Výsledky vyhledávání - "Eric, Merten"

Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro

Autor: Kareem A. Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy M. Havener, Michael E. Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed A. Helal, Emily R. Derbyshire, Reena Zutshi, David H. Drewry

Publikováno v: Journal of Medicinal Chemistry. 65:13172-13197

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9157dae09bb16f8beecc10edc94755ec
https://doi.org/10.1021/acs.jmedchem.2c00996

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Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial

Autor: Kareem A, Galal, Anna, Truong, Frank, Kwarcinski, Chandi, de Silva, Krisha, Avalani, Tammy M, Havener, Michael E, Chirgwin, Eric, Merten, Han Wee, Ong, Caleb, Willis, Ahmad, Abdelwaly, Mohamed A, Helal, Emily R, Derbyshire, Reena, Zutshi, David H, Drewry

Publikováno v: Journal of medicinal chemistry. 65(19)

Essential plasmodial kinases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::623b61b9dc64d8f7e83b1a7c940378b8
https://pubmed.ncbi.nlm.nih.gov/36166733

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Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity Against Blood Stage Parasites in vitro

Autor: Kareem Galal, Anna Truong, Frank Kwarcinski, Chandi de Silva, Krisha Avalani, Tammy Havener, Michael Chirgwin, Eric Merten, Han Wee Ong, Caleb Willis, Ahmad Abdelwaly, Mohamed Helal, Emily Derbyshire, Reena Zutshi, David Drewry

The plasmodial kinases PfGSK3 and PfPK6 have been identified as essential for the asexual life stage of Plasmodium falciparum, and thus are considered viable novel drug targets to combat rising resistance to traditional antimalarial drugs. We recentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77a07b433f8e6d1e238e150bf4065768
https://doi.org/10.26434/chemrxiv-2022-fpv0g

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Creating A System For Upstream - Downstream Fish Migration Over The First And The Second Discharge Sills Downstream Of Mănăştur Dam On The Someşul Mic River (Cluj Napoca, Transylvania, Romania)

Autor: Răzvan Voicu, Eric Merten

Publikováno v: Transylvanian Review of Systematical and Ecological Research, Vol 16, Iss 2, Pp 161-180 (2014)

The paper presents a case study that proposes a technical solution to facilitate fish migration upstream the discharge sills located on Someşul Mic River, near the Mănăştur Dam from the Cluj Napoca Town. The proposed solution provides building of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf04405141a3b9485c5bfa0ef85e26d
https://doaj.org/article/ee51e173b8974e17b7eec7054e38a1c2

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