Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Eric, Meldrum"'
Autor:
Maarten van der Linden, Sangeeta Kumari, Daphne Montizaan, Stephanie van Dalen, Annemarie Kip, Martyn Foster, Inge Reinieren-Beeren, Elsa Neubert, Luise Erpenbeck, Kelsy Waaijenberg, Tirza Bruurmijn, Rezie te Poele, Peter van Zandvoort, Paul Vink, Eric Meldrum, Helmuth van Es, Renato G.S. Chirivi
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTNeutrophil extracellular traps (NETs) contribute to the pathophysiology of multiple inflammatory and autoimmune diseases. Targeting the NETosis pathway has demonstrated significant therapeutic potency in various disease models. Here, we descr
Externí odkaz:
https://doaj.org/article/f1d4fae7078645b59627f1f002b651f7
Autor:
Henri-Baptiste Marjault, Ola Karmi, Ke Zuo, Dorit Michaeli, Yael Eisenberg-Domovich, Giulia Rossetti, Benoit de Chassey, Jacky Vonderscher, Ioav Cabantchik, Paolo Carloni, Ron Mittler, Oded Livnah, Eric Meldrum, Rachel Nechushtai
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Marjault et al. report two crystal structures of a drug molecule bound to NEET proteins mNT and NAF-1 and the effects of this molecule on diabetic mice, suggesting an approach for reducing mitochondrial iron and ROS levels in diabetic patients.
Externí odkaz:
https://doaj.org/article/5fdc9f8e63f74c36ac4f3fdb8fd0831a
Autor:
Irene Pila-Castellanos, Diana Molino, Joe McKellar, Laetitia Lines, Juliane Da Graca, Marine Tauziet, Laurent Chanteloup, Ivan Mikaelian, Laurène Meyniel-Schicklin, Patrice Codogno, Jacky Vonderscher, Cédric Delevoye, Olivier Moncorgé, Eric Meldrum, Caroline Goujon, Etienne Morel, Benoit de Chassey
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009485 (2021)
[This corrects the article DOI: 10.1371/journal.ppat.1009340.].
Externí odkaz:
https://doaj.org/article/4443840dff5f4f5f8db2ff83300ea059
Autor:
Irene Pila-Castellanos, Diana Molino, Joe McKellar, Laetitia Lines, Juliane Da Graca, Marine Tauziet, Laurent Chanteloup, Ivan Mikaelian, Laurène Meyniel-Schicklin, Patrice Codogno, Jacky Vonderscher, Cédric Delevoye, Olivier Moncorgé, Eric Meldrum, Caroline Goujon, Etienne Morel, Benoit de Chassey
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009340 (2021)
Influenza virus infections are major public health threats due to their high rates of morbidity and mortality. Upon influenza virus entry, host cells experience modifications of endomembranes, including those used for virus trafficking and replicatio
Externí odkaz:
https://doaj.org/article/811c473002d34a5981e5034b7202dc51
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002976 (2012)
Viruses use a limited set of host pathways for infection. These pathways represent bona fide antiviral targets with low likelihood of viral resistance. We identified the salicylanilide niclosamide as a broad range antiviral agent targeting acidified
Externí odkaz:
https://doaj.org/article/134bf5d7861149e199026a1f4a4cd933
Autor:
Ahmed Hamaï, Nivea Dias Amoedo, Francesca Giordano, Yang Sung Sohn, Peter Machin, Benoît de Chassey, Diana Molino, Patrice Codogno, Ola Karmi, Henri-Baptiste Marjault, Laetitia Lines, Irene Pila-Castellanos, Alessia Ruggieri, Damien Arnoult, Pauline Radreau, Rodrigue Rossignol, Etienne Morel, Eric Meldrum, Leila Rochin, Jacky Vonderscher, Rachel Nechushtai, Stéphane Joly, Katja Kopp
Publikováno v:
EMBO Rep
EMBO Reports
EMBO Reports, EMBO Press, 2020, 21 (12), ⟨10.15252/embr.201949019⟩
EMBO Reports, EMBO Press, 2020, ⟨10.15252/embr.201949019⟩
EMBO Reports
EMBO Reports, EMBO Press, 2020, 21 (12), ⟨10.15252/embr.201949019⟩
EMBO Reports, EMBO Press, 2020, ⟨10.15252/embr.201949019⟩
International audience; Several human pathologies including neurological, cardiac, infectious , cancerous, and metabolic diseases have been associated with altered mitochondria morphodynamics. Here, we identify a small organic molecule, which we name
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05b0954eedbb6d731ad6194e35c1b2c
https://pubmed.ncbi.nlm.nih.gov/33180995
https://pubmed.ncbi.nlm.nih.gov/33180995
Autor:
Ben, Nicholas, Karl J, Staples, Stefan, Moese, Eric, Meldrum, Jon, Ward, Patrick, Dennison, Tom, Havelock, Timothy S C, Hinks, Khalid, Amer, Edwin, Woo, Martin, Chamberlain, Neeta, Singh, Malcolm, North, Sandy, Pink, Tom M A, Wilkinson, Ratko, Djukanović
Publikováno v:
The Journal of Immunology Author Choice
Influenza A virus causes considerable morbidity and mortality largely because of a lack of effective antiviral drugs. Viral neuraminidase inhibitors, which inhibit viral release from the infected cell, are currently the only approved drugs for influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26abbd6ebc906c44b6efe943a8c2a335
https://pubmed.ncbi.nlm.nih.gov/25934861
https://pubmed.ncbi.nlm.nih.gov/25934861
Autor:
Ashish Kurundkar, Thomas D. Hock, Louise Hecker, Eric Meldrum, Victor J. Thannickal, Naomi J. Logsdon, Deepali Kurundkar, Yan Y. Sanders, Karen Bernard
Publikováno v:
Science translational medicine. 6(231)
The incidence and prevalence of pathological fibrosis increase with advancing age, although mechanisms for this association are unclear. We assessed the capacity for repair of lung injury in young (2 months) and aged (18 months) mice. Whereas the sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde573396fc682e58660b2dc7ca0fbae
https://pubmed.ncbi.nlm.nih.gov/25668226
https://pubmed.ncbi.nlm.nih.gov/25668226
Autor:
Elisabeth Allet, Therese Jamotte, Marie-Laure Curchod, François Talabot, Fabrizio Arigoni, Michael D. Edgerton, Manuel C. Peitsch, Hannes Loferer, Richard Fish, Eric Meldrum
Publikováno v:
Scopus-Elsevier
We have used comparative genomics to identify 26 Escherichia coli open reading frames that are both of unknown function (hypothetical open reading frames or y-genes) and conserved in the compact genome of Mycoplasma genitalium. Not surprisingly, thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4b28f8fc9b0bda7cbf979904c37b9c
https://doi.org/10.1038/nbt0998-851
https://doi.org/10.1038/nbt0998-851