Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Eric, Ibsen"'
Autor:
Eric Ibsen
Publikováno v:
The Journal of Immunology. 208:173.01-173.01
A 2012 study published by Amgen researchers found that 90% of the in vivo oncology studies were not reproducible. Historically, 95% of post-phase III oncology clinical trial therapies failed to receive regulatory approval due to a lack of demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255fef53d7d958b066dcc365a270b0a1
https://doi.org/10.4049/jimmunol.208.supp.173.01
https://doi.org/10.4049/jimmunol.208.supp.173.01
Autor:
Hannes Hentze, Eric Ibsen
Publikováno v:
Cancer Research. 79:90-90
Historically, a large majority of clinical phase III trials fail to gain regulatory approval due primarily to a lack of demonstrated efficacy, demonstrating the challenge of conducting clinically relevant efficacy studies in laboratory animals. In 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94644186d6554da283f8898c1c50f8ba
https://doi.org/10.1158/1538-7445.am2019-90
https://doi.org/10.1158/1538-7445.am2019-90
Autor:
Eric Ibsen, Jeffrey L. Kumer
Publikováno v:
Cancer Research. 75:1555-1555
To more closely emulate clinical research methodology, researchers are increasingly utilizing clinically-similar group randomization and distribution methods for oncology studies in animals. It has been common practice to re-house animals into new ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03198d48209773a4a7688584e1304765
https://doi.org/10.1158/1538-7445.am2015-1555
https://doi.org/10.1158/1538-7445.am2015-1555
Autor:
Vinay, Bhaskar, Debbie A, Law, Eric, Ibsen, Danna, Breinberg, Kellie M, Cass, Robert B, DuBridge, Ferdinand, Evangelista, Susan M, Henshall, Peter, Hevezi, Jennifer C, Miller, Melody, Pong, Rick, Powers, Peter, Senter, David, Stockett, Robert L, Sutherland, Ursula, von Freeden-Jeffry, Dorian, Willhite, Richard, Murray, Daniel E H, Afar, Vanitha, Ramakrishnan
Publikováno v:
Cancer research. 63(19)
We have used the Eos Hu03 GeneChip array, which represents over 92% of the transcribed human genome, to measure gene expression in a panel of normal and diseased human tissues. This analysis revealed that E-selectin mRNA is selectively overexpressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab45a1c63c9da94faa3b13132630f556
https://pubmed.ncbi.nlm.nih.gov/14559828
https://pubmed.ncbi.nlm.nih.gov/14559828
Autor:
Eric Ibsen, Jeffrey L. Kumer
Publikováno v:
Cancer Research. 74:3498-3498
The use of software applications to automate the workflow specific to preclinical oncology trials can significantly improve labor efficiency, data quality & security while preserving both methodology and results in a searchable database in perpetuity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d98c3fcdb8296b8248b68117331a82d0
https://doi.org/10.1158/1538-7445.am2014-3498
https://doi.org/10.1158/1538-7445.am2014-3498
Publikováno v:
Cancer Research. 74:4190-4190
To more closely emulate clinical research methodology and improve clinical relevance, researchers are increasingly utilizing clinically-similar group randomization and distribution methods for oncology studies in animals. One common pre-clinical appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad9e735ea6c1aa5c8338b0352dd8c094
https://doi.org/10.1158/1538-7445.am2014-4190
https://doi.org/10.1158/1538-7445.am2014-4190
Autor:
Eric Ibsen, Jeff Kumer
Publikováno v:
The Journal of Immunology. 192:49.8-49.8
To more closely emulate clinical research methodology and improve clinical relevance, researchers are increasingly utilizing more clinically-similar group randomization and distribution methods for Inflammation studies in animals. A common pre-clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448bd1843a526a9e211bc2b4f76460b9
https://doi.org/10.4049/jimmunol.192.supp.49.8
https://doi.org/10.4049/jimmunol.192.supp.49.8
Autor:
Jeffrey Kumer, Eric Ibsen
Publikováno v:
The FASEB Journal. 28:1053.7
To closely emulate clinical research methodology and improving clinical relevance, researchers are utilizing clinically-similar group randomization and distribution methods for pre-clinical studies...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d91f38a89f72b29e2cb0109d22dd042
https://doi.org/10.1096/fasebj.28.1_supplement.1053.7
https://doi.org/10.1096/fasebj.28.1_supplement.1053.7
Autor:
Eric Ibsen
Publikováno v:
Clinical Immunology. 131:S79-S80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d60c97aaa48f9e7e8d3bcae61ef89e2
https://doi.org/10.1016/j.clim.2009.03.233
https://doi.org/10.1016/j.clim.2009.03.233
Autor:
Jeff Kumer, Eric Ibsen
Publikováno v:
The Journal of Immunology. 188:124.16-124.16
The traditional management of immunological animal studies and results is challenging due to complex, varied workflows as well as the acquisition, analysis, secure storage and accessibility of disparate data types acquired and stored in multiple form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de3a9b1ff534c6e40b69e81050d70a58
https://doi.org/10.4049/jimmunol.188.supp.124.16
https://doi.org/10.4049/jimmunol.188.supp.124.16