Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Eric, Hoffman"'
Autor:
Laurie Conklin, Eric Hoffman, Suzanne Gaglianone, Rahel Ketema, Wangshu Tu, Holly Peay, Paula Clemens, Utkarsh Dang
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objectives Public access databases such as clinicaltrials.gov achieve dissemination of clinical trial design and aggregated study results. However, return of participant-level data is rarely done. A key barrier includes the proprietary ownership of d
Externí odkaz:
https://doaj.org/article/96818effd8304a778d01a7e28f521fe5
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Darshana Sirisena, Harsha Gunasekara, Athula Dissanayake, Sunethra Senanayake, Ajantha Keshavaraj, Yetrib Hathout, Harry W.M. Steinbusch, Chandra Mohan, Ashwin Dalal, Eric Hoffman, K.Ranil D de Silva
Publikováno v:
IBRO Neuroscience Reports, Vol 14, Iss , Pp 146-153 (2023)
Background: In this article, the authors discuss how they utilized the genetic mutation data in Sri Lankan Duchenne muscular dystrophy (DMD), Spinal muscular atrophy (SMA), Spinocerebellar ataxia (SCA) and Huntington’s disease (HD) patients and com
Externí odkaz:
https://doaj.org/article/4ac8bd1ca053427ab5295e8573dda7c8
Autor:
Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Pulasthi Dissanayaka, Isuru Gunarathne, Dhammika Amaratunga, Roshan Liyanage, Sunethra Senanayaka, Saraji Wijesekara, Hemal H. Gunasekara, Kamala Vanarsa, Jessica Castillo, Yetrib Hathout, Ashwin Dalal, Harry W.M. Steinbusch, Eric Hoffman, Chandra Mohan, K. Ranil D. de Silva
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18530- (2023)
Introduction: Documented Duchenne Muscular Dystrophy (DMD) biomarkers are confined to Caucasians and are poor indicators of cognitive difficulties and neuropsychological alterations. Materials and methods: This study correlates serum protein signatur
Externí odkaz:
https://doaj.org/article/ea7f989c48ed46f8ad872ba9e802e1d3
Autor:
Kelsey Dawes, Allan Andersen, Rachel Reimer, James A. Mills, Eric Hoffman, Jeffrey D. Long, Shelly Miller, Robert Philibert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose dependency of that response is as of yet unclear. This lack of certainty is a barri
Externí odkaz:
https://doaj.org/article/f9a2397189974920a5250144371a2f3c
Publikováno v:
Fire, Vol 6, Iss 8, p 302 (2023)
Efforts to delineate the influence of atmospheric variability on regional wildfire activity have previously been complicated by the stochastic occurrence of ignition and large fire events, particularly for Southern California, where anthropogenic mod
Externí odkaz:
https://doaj.org/article/667613eedaaf4cf6be402b07bf706bf6
Autor:
Dheyaa Alkhanfar, Yousef Shahin, Faisal Alandejani, Krit Dwivedi, Samer Alabed, Chris Johns, Allan Lawrie, A.A. Roger Thompson, Alexander M.K. Rothman, Juerg Tschirren, Johanna M. Uthoff, Eric Hoffman, Robin Condliffe, Jim M. Wild, David G. Kiely, Andrew J. Swift
Publikováno v:
ERJ Open Research, Vol 8, Iss 2 (2022)
Background Pulmonary hypertension (PH) in patients with chronic lung disease (CLD) predicts reduced functional status, clinical worsening and increased mortality, with patients with severe PH-CLD (≥35 mmHg) having a significantly worse prognosis th
Externí odkaz:
https://doaj.org/article/732a4476b3e442a5888ac4c4700722c6
Publikováno v:
Evolutionary Applications, Vol 13, Iss 4, Pp 752-767 (2020)
Abstract The adaptive potential of invasive species is related to the genetic diversity of the invader, which is influenced by genetic drift and natural selection. Typically, the genetic diversity of invaders is studied with neutral genetic markers;
Externí odkaz:
https://doaj.org/article/4b2fae53e30147b9b58b7347be62685f
Publikováno v:
Bio-Protocol, Vol 11, Iss 17 (2021)
Missense mutations in leucine rich-repeat kinase 2 (LRRK2) cause forms of familial Parkinson’s disease and have been linked to ‘idiopathic’ Parkinson’s disease. Assessment of LRRK2 kinase activity has been very challenging due to its size, co
Externí odkaz:
https://doaj.org/article/9877a7a17d644d1c87f28fb8afcec962
Publikováno v:
Global Pediatric Health, Vol 8 (2021)
Pediatric obesity is a major health concern today, which pre-disposes individuals to metabolic syndrome (MS), and the risk of premature cardiovascular disease (CVD). Use of carotid intima media thickness (CIMT) is recognized as non-invasive way to as
Externí odkaz:
https://doaj.org/article/27385582312c46d6809792d43a7b7fdd
Autor:
Bina Choi, Steven M. Kawut, Ganesh Raghu, Eric Hoffman, Russell Tracy, Purnema Madahar, Elana J. Bernstein, R. Graham Barr, David J. Lederer, Anna Podolanczuk
Publikováno v:
ERJ Open Research, Vol 6, Iss 1 (2020)
High-attenuation areas (HAA) are a computed tomography-based quantitative measure of subclinical interstitial lung disease (ILD). We aimed to validate HAA in lung regions that are less subject to artefacts, such as extravascular lung water or depende
Externí odkaz:
https://doaj.org/article/34937b4f56a04d49b85f02c728411953