Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Eric, Haines"'
Autor:
Eric Haines, Tomas Akenine-Möller
This book is a must-have for anyone serious about rendering in real time. With the announcement of new ray tracing APIs and hardware to support them, developers can easily create real-time applications with ray tracing as a core component. As ray tra
Autor:
Eric Haines, Yuki Nishida, Michael I. Carr, Rafael Heinz Montoya, Lauren B. Ostermann, Weiguo Zhang, Frank T. Zenke, Andree Blaukat, Michael Andreeff, Lyubomir T. Vassilev
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Peposertib (M3814) is a potent and selective DNA-PK inhibitor in early clinical development. It effectively blocks non-homologous end-joining repair of DNA double-strand breaks (DSB) and strongly potentiates the antitumor effect of ionizing
Externí odkaz:
https://doaj.org/article/36b7c6a88d6e4d8b9b33159cd731cb9e
Autor:
Jun Ma, Kristen Hurov, Johanna lahdenranta, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen, Fanglei You, Mike Kelly, Heather Cohen, Drasti Kanakia, Carly Campbell, David Witty, Stephen Blakemore, Phil Jeffrey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/4724c01b9ec7407d90abf3570e647883
Autor:
Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen, Rachel Dods, Rachid Lani, Katerine Van Rietschoten, Tom Stephen, Fanglei You
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background In contrast to immune checkpoint inhibitors, the use of antibodies as agonists of immune costimulatory receptors as cancer therapeutics has largely failed. We sought to address this problem using a new class of modular synthetic drugs, ter
Externí odkaz:
https://doaj.org/article/2beebb8f72534439867cc69dff340982
Autor:
Jun Ma, Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/6541410690f84d4cbbca57e8c0959953
Supplementary Data from CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Autor:
Kwok-Kin Wong, Nathanael S. Gray, David A. Barbie, Geoffrey I. Shapiro, Haribabu Arthanari, Norman E. Sharpless, W. Nicholas Haining, Jerome Ritz, Gordon J. Freeman, Sangeetha Palakurthi, Raphael Bueno, Genevieve M. Boland, Viswanath Gunda, Sareh Parangi, Jochen H. Lorch, William G. Richards, Jay C. Strum, Patrick J. Roberts, Eric Haines, Amanda J. Rode, Megan E. Cavanaugh, Ting Chen, Peng Gao, Hua Zhang, Yanxi Zhang, Annan Yang, Lauren E. Bufe, Max M. Quinn, Ashley A. Merlino, Patrick H. Lizotte, John E. Bisi, Jessica A. Sorrentino, Grit S. Herter-Sprie, Chensheng W. Zhou, Michaela Bowden, Cloud P. Paweletz, Elena Ivanova, Amir R. Aref, Hongye Liu, Wei Huang, Sandeep Chhabra, Kathleen Yates, Ruben Dries, Shuai Li, Russell W. Jenkins, Eric S. Wang, Jiehui Deng
Figure S1. Characterization of cells and CDK4/6 inhibitors; Figure S2. CDK6 phosphorylates serine residues of the regulatory domain of NFAT4 (NFATc3); Figure S3. Analysis of lung tumor immune infiltrates after CDK4/6 inhibition from KrasG12D (Kras),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a01c7e72b06ed917fff29065c873f6
https://doi.org/10.1158/2159-8290.22531849.v1
https://doi.org/10.1158/2159-8290.22531849.v1
Autor:
Kevin Lee, Nicholas Keen, Phil Jeffrey, Michael J. Skynner, Johanna Lahdenranta, Eric Haines, Carly Campbell, Peter U. Park, Amy N. Brown, Heather S. Scott, Sophie M. Watcham, Katerine Van Rietschoten, Paul J. Beswick, Helen Harrison, Gemma E. Mudd, Liuhong Chen, Gavin Bennett, Michael Rigby
Supplementary Figure from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0148ec0572dcf04288b6c7ac55148911
https://doi.org/10.1158/1535-7163.22523875
https://doi.org/10.1158/1535-7163.22523875
Autor:
Kristen Hurov, Lia Luus, Johanna Lahdenranta, Punit Upadhyaya, Heather Cohen, Chinmayee Shah, Julia Kristensson, Peter Brown, Gemma Mudd, Carly Campbell, Elizabeth Repash, Eric Haines, Sailaja Battula, Mike Kelly, Phil Jeffrey, Paul Beswick, Liuhong Chen, Kevin McDonnell, Philip Brandish, Nicholas Keen
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f969126e40fad5d1270f04621dffbb4
https://doi.org/10.1136/jitc-2022-sitc2022.1340
https://doi.org/10.1136/jitc-2022-sitc2022.1340
Autor:
Eric Haines, Michael Burke, Rachel Catterall, Victor De Jesus, Bin Li, Joseph D. Manna, George Punkosdy, Oksana Zavidij, Sarah R. Wessel, Grace Werosta, Jill Cavanaugh, Sheila Newhouse, Aravind Basavapathruni, Lan Xu, Sergio Santillana, X. Michelle Zhang, Sabine K. Ruppel
Publikováno v:
Molecular Cancer Research. 21:PR10-PR10
Alterations in the RAS/RAF/MEK/ERK pathway are the most common drivers of oncogenesis. Although MEK is a clinically validated cancer target and several MEK inhibitors have been approved by the FDA, their clinical utility is limited to BRAFV600 mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f2462c249dd35c7b1ef3c0266b05ea
https://doi.org/10.1158/1557-3125.ras23-pr10
https://doi.org/10.1158/1557-3125.ras23-pr10
Publikováno v:
Procedia Manufacturing. 48:598-605
The thermomechanical interaction between the cutting tool and the workpiece in any material removal process is a key factor in defining the efficiency and productivity of the process. It is especially important in cutting hard-to-machine materials su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::966ab119b8b7317dd33014c655237641
https://doi.org/10.1016/j.promfg.2020.05.087
https://doi.org/10.1016/j.promfg.2020.05.087