Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Eric, Gracey"'
Autor:
Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, Tino Hochepied, Christian Vanhove, Eric Gracey, Emilie Dumas, Teddy Manuelo, Ivan Josipovic, Geert vanLoo, Dirk Elewaut, Lars Vereecke
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Arthritis is the most common extra‐intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shar
Externí odkaz:
https://doaj.org/article/6cc505e181ba4edfa275d745f425476b
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Spondyloarthritis (SpA) is a family of inflammatory arthritic diseases, which includes the prototypes of psoriatic arthritis and ankylosing spondylitis. SpA is commonly associated with systemic inflammatory diseases, such as psoriasis and inflammator
Externí odkaz:
https://doaj.org/article/22ca145550bf40e8a4524ba0ca06a197
Autor:
Céline Mortier, Eric Gracey, Julie Coudenys, Teddy Manuello, Tine Decruy, Margaux Maelegheer, Flore Stappers, Elisabeth Gilis, Djoere Gaublomme, Luc Van Hoorebeke, Sophie Van Welden, Catherine Ambler, Martin Hegen, Peter Symanowicz, Stefan Steyn, Gabriel Berstein, Dirk Elewaut, Koen Venken
Publikováno v:
Rheumatology.
Objective Divergent therapeutic outcomes on different disease domains have been noted with IL-23 and IL-17A-blockade in PsA. Therefore, elucidating the role of RORγt, the master regulator of type 17 immune responses, is of potential therapeutic inte
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150515 (2016)
The development and progression of systemic lupus erythematosus is mediated by the complex interaction of genetic and environmental factors. To decipher the genetics that contribute to pathogenesis and the production of pathogenic autoantibodies, our
Externí odkaz:
https://doaj.org/article/1838f4f2307843e991e7cccc63e87170
Autor:
Dermot P.B. McGovern, Martine De Vos, Silvio Danese, Eric Gracey, Dirk Elewaut, Filip Van den Bosch, Mareike Fröhling, Lars Vereecke, Georg Schett
Publikováno v:
Nature Reviews Rheumatology. 16:415-433
Gut inflammation is strongly associated with spondyloarthritis (SpA), as exemplified by the high prevalence of inflammatory bowel disease (IBD) and the even higher occurrence of subclinical gut inflammation in patients with SpA. The gut-joint axis of
Publikováno v:
Arthritis & Rheumatology. 72:428-434
Objective Ankylosing spondylitis (AS) is an inflammatory arthritis in which men have a higher risk of developing progressive axial disease than women. Transcriptomic studies have shown reduced expression of cytotoxic cell genes in the blood of AS pat
Autor:
Roman V. Chernozem, Igor Pariy, Maria A. Surmeneva, Vladimir V. Shvartsman, Guillaume Planckaert, Joost Verduijn, Stef Ghysels, Anatolii Abalymov, Bogdan V. Parakhonskiy, Eric Gracey, Amanda Gonçalves, Sanjay Mathur, Frederik Ronsse, Diederik Depla, Doru C. Lupascu, Dirk Elewaut, Roman A. Surmenev, Andre G. Skirtach
Publikováno v:
Advanced Healthcare Materials. 12:2201726
This is the first comprehensive study of the impact of biodegradation on the structure, surface potential, mechanical and piezoelectric properties of poly(3-hydroxybutyrate) (PHB) scaffolds supplemented with reduced graphene oxide (rGO) as well as ce
Autor:
Robert D. Inman, Shaghayegh Foroozan Boroojeni, Rohan Machhar, Ye-Soo Park, Kyle T. Reid, Igor Jurisica, E. Rossomacha, Tae-Hwan Kim, Masaki Kusuda, Brian Wu, Nigil Haroon, Richard Bucala, S. Nakamura, Sungsin Jo, Jason S. Rockel, Melissa Lim, Fanxing Zeng, Sarah Q. Crome, Akihiro Nakamura, Mohit Kapoor, Eric Gracey, Francesco Ciccia, Lin Leng
Publikováno v:
Science translational medicine. 13(616)
Spondyloarthritis (SpA), a type 3 immunity-mediated inflammatory arthritis, is a systemic rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, yet
Publikováno v:
Annals of the Rheumatic Diseases. 78:1566-1575
ObjectivesCurrent evidence suggests that immune events in the gut may impact joint inflammation in ankylosing spondylitis (AS) but the expression of gut-related trafficking molecules in the inflammed joint is poorly characterised. We aimed to (1) ass
Publikováno v:
Current Opinion in Rheumatology. 31:62-69
Purpose of review This article aims to review recent literature linking epithelial barrier inflammation and arthritis in spondyloarthritis (SpA), with a critical view on how they are bound by genetic, immunological and environmental ties. Recent find