Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Eric, Fabbrizio"'
Autor:
Alice Matheux, Matthieu Gassiot, Gaëlle Fromont, Fanny Leenhardt, Abdelhay Boulahtouf, Eric Fabbrizio, Candice Marchive, Aurélie Garcin, Hanane Agherbi, Eve Combès, Alexandre Evrard, Nadine Houédé, Patrick Balaguer, Céline Gongora, Litaty C. Mbatchi, Philippe Pourquier
Publikováno v:
Cancers, Vol 13, Iss 14, p 3635 (2021)
Resistance to castration is a crucial issue in the treatment of metastatic prostate cancer. Kinase inhibitors (KIs) have been tested as potential alternatives, but none of them are approved yet. KIs are subject of extensive metabolism at both the hep
Externí odkaz:
https://doaj.org/article/f003674c659b437bb1cb5987b6cbcad3
Publikováno v:
Biology Open, Vol 4, Iss 3, Pp 312-316 (2015)
Protein arginine methyl transferase 5 (Prmt5) regulates various differentiation processes, including adipogenesis. Here, we investigated adipogenic conversion in cells and mice in which Copr5, a Prmt5- and histone-binding protein, was genetically inv
Externí odkaz:
https://doaj.org/article/04b8a6c79ac94e308211715ab375ac7b
Autor:
Akeila Bellahcene, Roberto Ronca, Guillaume Belthier, Patrick Balaguer, Simon Lacroix, Paola Chiodelli, Gaetan Van Simaeys, Andrei Turtoi, Barbara Chiavarina, Julie Pannequin, Olivier Detry, Guy Jerusalem, Serge Goldman, Stéphanie Gofflot, Arnaud Blomme, Eric Fabbrizio, Sara Rezzola, Gilles Doumont, Ambre Giguelay, Bilguun Erkhem-Ochir, Takehiko Yokobori, Vincent Castronovo, Brunella Costanza, Philippe Delvenne, Vincent Cavaillès, Emmanuel Di Valentin
Publikováno v:
Theranostics
Theranostics, 11 (4
Theranostics, Ivyspring International Publisher, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 11 (4
Theranostics, Ivyspring International Publisher, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Theranostics, 2021, 11 (4), pp.1626-1640. ⟨10.7150/thno.51507⟩
Colorectal cancer (CRC) cells are traditionally considered unresponsive to TGFβ due to mutations in the receptors and/or downstream signaling molecules. TGFβ influences CRC cells only indirectly via stromal cells, such as cancer-associated fibrobla
Autor:
Marine Pratlong, Eric Fabbrizio, Lakdhar Khellaf, Nelly Pirot, Amélie Sarrazin, Damien Grégoire, Yannick Perez, Shefqet Hajdari, Jean-Yohan Noël, Eric Julien, Nehmé Saksouk, Aliki Zavoriti, Florence Cammas, Céline Graber, Célia Barrachina
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2020, 39 (13), pp.2676-2691. ⟨10.1038/s41388-020-1177-8⟩
Oncogene, Nature Publishing Group, 2020, 39 (13), pp.2676-2691. ⟨10.1038/s41388-020-1177-8⟩
International audience; Chromatin organization is essential for appropriate interpretation of the genetic information. Here, we demonstrated that the chromatin associated proteins HP1 are dispensable for hepatocytes survival but are essential within
Autor:
Hanane Agherbi, Fanny Leenhardt, Litaty Mbatchi, Aurélie Garcin, Philippe Pourquier, Alexandre Evrard, Candice Marchive, Alice Matheux, Matthieu Gassiot, Nadine Houede, Abdelhay Boulahtouf, Gaëlle Fromont, Patrick Balaguer, Eve Combes, Céline Gongora, Eric Fabbrizio
Publikováno v:
Cancers
Cancers, MDPI, 2021, 13 (14), pp.3635. ⟨10.3390/cancers13143635⟩
Cancers, Vol 13, Iss 3635, p 3635 (2021)
Volume 13
Issue 14
Cancers, 2021, 13 (14), pp.3635. ⟨10.3390/cancers13143635⟩
Cancers, MDPI, 2021, 13 (14), pp.3635. ⟨10.3390/cancers13143635⟩
Cancers, Vol 13, Iss 3635, p 3635 (2021)
Volume 13
Issue 14
Cancers, 2021, 13 (14), pp.3635. ⟨10.3390/cancers13143635⟩
Simple Summary Many kinase inhibitors have been tested as potential alternatives for the treatment of castration-resistant prostate cancers. However, none of these clinical trials led to drug approval despite interesting responses. Our study reveals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f062d9bf24ee05e9d11136cdd20d6ac
https://hal.archives-ouvertes.fr/hal-03450785
https://hal.archives-ouvertes.fr/hal-03450785
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2020, 477 (5), pp.1033-1047. ⟨10.1042/BCJ20190621⟩
Biochemical Journal, Portland Press, 2020, 477 (5), pp.1033-1047. ⟨10.1042/BCJ20190621⟩
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer in adults. Among the altered pathways leading to HCC, an increasing role is attributed to abnormal epigenetic regulation. Members of the Heterochromatin Protein (HP1) 1 family a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d05566ee2bd803dd4af6e459ffacf4c
https://hal.archives-ouvertes.fr/hal-03012648
https://hal.archives-ouvertes.fr/hal-03012648
Autor:
Anais Giry, Emilio Casanova, Gilles Favre, Olivier Calvayrac, Jean-Charles Soria, Irene Ferrer, Laura Papon, Yaël Glasson, Julien Mazieres, Nelly Pirot, Luis Paz-Ares, Antonio Maraver, Andrei Turtoi, Kwok-Kin Wong, Jean-Louis Pujol, Eric Fabbrizio, Sara Bernardo, Yosef Yarden, Marion Goussard, Herwig P. Moll, Jacques Colinge, Marta Cañamero, Emilie Bousquet Mur, Christian W. Siebel, Xavier Quantin, Maicol Mancini
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2019, 130 (2), pp.612-624. ⟨10.1172/JCI126896⟩
J Clin Invest
Journal of Clinical Investigation, American Society for Clinical Investigation, 2019, 130 (2), pp.612-624. ⟨10.1172/JCI126896⟩
J Clin Invest
EGFR-mutated lung adenocarcinoma patients treated with gefitinib and osimertinib show a therapeutic benefit limited by the appearance of secondary mutations, such as EGFR(T790M) and EGFR(C797S). It is generally assumed that these secondary mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7700de860d77435e97cb9217e2123312
https://hal.archives-ouvertes.fr/hal-03025960
https://hal.archives-ouvertes.fr/hal-03025960
Autor:
Nehmé, Saksouk, Shefqet, Hajdari, Yannick, Perez, Marine, Pratlong, Célia, Barrachina, Céline, Graber, Damien, Grégoire, Aliki, Zavoriti, Amélie, Sarrazin, Nelly, Pirot, Jean-Yohan, Noël, Lakhdar, Khellaf, Eric, Fabbrizio, Eric, Julien, Florence M, Cammas
Publikováno v:
Oncogene. 39(13)
Chromatin organization is essential for appropriate interpretation of the genetic information. Here, we demonstrated that the chromatin-associated proteins HP1 are dispensable for hepatocytes survival but are essential within hepatocytes to prevent l
Autor:
Jean-Yohan Noël, Aliki Zavoriti, Amélie Sarrazin, Shefqet Hajdari, Céline Graber, Eric Julien, Eric Fabbrizio, Célia Barrachina, Nelly Pirot, Nehmé Saksouk, Lakhdar Khellaf, Marine Pratlong, Florence Cammas
Chromatin organization is essential for appropriate interpretation of the genetic information. Here, we demonstrated that the chromatin associated proteins HP1 are dispensable for cell survival but are essential within hepatocytes to prevent liver tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853c5a4cb59991f773a9c94266371e52
https://doi.org/10.1101/441279
https://doi.org/10.1101/441279
Autor:
Conception, Paul, Hélène, Delpech, Delphine, Haouzi, Samir, Hamamah, Claude, Sardet, Eric, Fabbrizio
Publikováno v:
FEBS Open Bio
Repression of retrotransposons is essential for genome integrity during germ cell development and is tightly controlled through epigenetic mechanisms. In primordial germ cells, protein arginine N‐methyltransferase (Prmt5) is involved in retrotransp