Zobrazeno 1 - 10
of 689
pro vyhledávání: '"Eric, Deutsch"'
Autor:
Paul Bergeron, Morgane Dos Santos, Lisa Sitterle, Georges Tarlet, Jeremy Lavigne, Winchygn Liu, Marine Gerbé de Thoré, Céline Clémenson, Lydia Meziani, Cathyanne Schott, Giulia Mazzaschi, Kevin Berthelot, Mohamed Amine Benadjaoud, Fabien Milliat, Eric Deutsch, Michele Mondini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The efficacy and side effects of radiotherapy (RT) depend on parameters like dose and the volume of irradiated tissue. RT induces modulations of the tumor immune microenvironment (TIME) that are dependent on the dose. Low dose RT (LDRT, i.e.
Externí odkaz:
https://doaj.org/article/87cbab60703e412d95b5a9f2a002e7a8
Autor:
Antonin Levy, Daphné Morel, Matthieu Texier, Roger Sun, Jerome Durand-Labrunie, Maria E Rodriguez-Ruiz, Severine Racadot, Stéphane Supiot, Nicolas Magné, Stacy Cyrille, Guillaume Louvel, Christophe Massard, Loic Verlingue, Fanny Bouquet, Alberto Bustillos, Lisa Bouarroudj, Clément Quevrin, Céline Clémenson, Michele Mondini, Lydia Meziani, Lambros Tselikas, Rastilav Bahleda, Antoine Hollebecque, Eric Deutsch
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Immuno-radiotherapy may improve outcomes for patients with advanced solid tumors, although optimized combination modalities remain unclear. Here, we report the colorectal (CRC) cohort analysis from the SABR-PDL1 trial that evaluat
Externí odkaz:
https://doaj.org/article/e2332711ee644fd79fb6e8ed2a5b6190
Autor:
Rahimeh Rouhi, Stéphane Niyoteka, Alexandre Carré, Samir Achkar, Pierre-Antoine Laurent, Mouhamadou Bachir Ba, Cristina Veres, Théophraste Henry, Maria Vakalopoulou, Roger Sun, Sophie Espenel, Linda Mrissa, Adrien Laville, Cyrus Chargari, Eric Deutsch, Charlotte Robert
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 30, Iss , Pp 100578- (2024)
Background and Purpose: Automatic segmentation methods have greatly changed the RadioTherapy (RT) workflow, but still need to be extended to target volumes. In this paper, Deep Learning (DL) models were compared for Gross Tumor Volume (GTV) segmentat
Externí odkaz:
https://doaj.org/article/4f8d8ae90c1e4b03873351f3036e4c9c
Autor:
Pierre-Antoine Laurent, Marina Milic, Clément Quevrin, Lydia Meziani, Winchygn Liu, Daphné Morel, Nicolas Signolle, Céline Clémenson, Antonin Levy, Michele Mondini, Eric Deutsch
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background KRAS activating mutations are considered the most frequent oncogenic drivers and are correlated with radio-resistance in multiple cancers including non-small cell lung cancer (NSCLC) and colorectal cancer. Although KRAS was consid
Externí odkaz:
https://doaj.org/article/3cb7ef32273d492aa7ecc6fa21b1b5de
Autor:
Arthur Durand, Tatiana Borisova, François Lux, Jordyn A Howard, Augustin Tillement, Halyna Kuznietsova, Natalia Dziubenko, Vladimir Lysenko, Laurent David, Daphné Morel, Ross Berbeco, Serhiy Komisarenko, Olivier Tillement, Eric Deutsch
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0292414 (2024)
To mitigate the risk of radioactive isotope dissemination, the development of preventative and curative measures is of particular interest. For mass treatment, the developed solution must be easily administered, preferably orally, with effective, non
Externí odkaz:
https://doaj.org/article/313fb066bc2846b9906947735acc4784
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTChimeric antigen receptor (CAR)-T cells have demonstrated significant improvements in the treatment of refractory B-cell malignancies that previously showed limited survival. In contrast, early-phase clinical studies targeting solid tumors ha
Externí odkaz:
https://doaj.org/article/bee54b8463514ee39143370c9c227a1f
Autor:
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L. Guzman, Kevin Harrington, Fernanda G. Herrera, Jamie Honeychurch, Theodore Hong, Lorea Iturri, Elisabeth Jaffee, Sana D. Karam, Simon R.V. Knott, Constantinos Koumenis, David Lyden, Ariel E. Marciscano, Alan Melcher, Michele Mondini, Anna Mondino, Zachary S. Morris, Sean Pitroda, Sergio A. Quezada, Laura Santambrogio, Stephen Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph Weichselbaum, James Welsh, Anna Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Silvia C. Formenti
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTFocal radiation therapy (RT) has attracted considerable attention as a combinatorial partner for immunotherapy (IT), largely reflecting a well-defined, predictable safety profile and at least some potential for immunostimulation. However, onl
Externí odkaz:
https://doaj.org/article/420f3d04260044b482062ca48125b481
Autor:
Antonin Levy, Jonathan Khalifa, Etienne Martin, Angela Botticella, Clément Quevrin, Pernelle Lavaud, Mihaela Aldea, Benjamin Besse, David Planchard, Fabrice Barlesi, Eric Deutsch, Carole Massabeau, Jérôme Doyen, Cécile Le Péchoux
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 41, Iss , Pp 100637- (2023)
Introduction: The role of local ablative treatments, including stereotactic body radiotherapy (SBRT), is an area of active research in oligometastatic patients. Small cell lung cancer (SCLC) has a poor prognosis, with common diffuse metastatic evolut
Externí odkaz:
https://doaj.org/article/c92fcb16210c45e78b303dcdc65081ef
Autor:
Anna Gueiderikh, Thomas Sarrade, Youlia Kirova, Brigitte De La Lande, Florent De Vathaire, Guillaume Auzac, Anne Laure Martin, Sibille Everhard, Nicolas Meillan, Celine Bourgier, Ahmed Benyoucef, Thomas Lacornerie, David Pasquier, Séverine Racadot, Alexandra Moignier, François Paris, Fabrice André, Eric Deutsch, Boris Duchemann, Rodrigue Setcheou Allodji, Sofia Rivera
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeRadiation-induced lung injury (RILI) is strongly associated with various clinical conditions and dosimetric parameters. Former studies have led to reducing radiotherapy (RT) doses to the lung and have favored the discontinuation of tamoxifen d
Externí odkaz:
https://doaj.org/article/ea5a25b9b3ba4c42aa9f597be8748f8c
Autor:
Pierre-Antoine Laurent, Eric Deutsch, Michele Mondini, Marine Gerbé De Thoré, Winchygn Liu, Lydia Meziani, Céline Clémenson, Marie-Catherine Vozenin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Irradiation (IR) and immune checkpoint inhibitor (ICI) combination is a promising treatment modality. However, local and distance treatment failure and resistance can occur. To counteract this resistance, several studies propose CD73, an e
Externí odkaz:
https://doaj.org/article/10e8b02d28fd4ab6a7ffa2fa982f0b9d