Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Eric, Courchesne"'
Autor:
Veronica Mandelli, Ines Severino, Lisa Eyler, Karen Pierce, Eric Courchesne, Michael V. Lombardo
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Phenotypic heterogeneity in early language, intellectual, motor, and adaptive functioning (LIMA) features are amongst the most striking features that distinguish different types of autistic individuals. Yet the current diagnostic
Externí odkaz:
https://doaj.org/article/76d399662f984017bf9ba76818ba2585
Autor:
Kuaikuai Duan, Lisa Eyler, Karen Pierce, Michael V. Lombardo, Michael Datko, Donald J. Hagler, Vani Taluja, Javad Zahiri, Kathleen Campbell, Cynthia Carter Barnes, Steven Arias, Srinivasa Nalabolu, Jaden Troxel, Peng Ji, Eric Courchesne
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Language and social symptoms improve with age in some autistic toddlers, but not in others, and such outcome differences are not clearly predictable from clinical scores alone. Here we aim to identify early-age brain alterations in autism th
Externí odkaz:
https://doaj.org/article/a0c3f4d162474ff2867858421f86f0ad
Autor:
Eric Courchesne, Vani Taluja, Sanaz Nazari, Caitlin M. Aamodt, Karen Pierce, Kuaikuai Duan, Sunny Stophaeros, Linda Lopez, Cynthia Carter Barnes, Jaden Troxel, Kathleen Campbell, Tianyun Wang, Kendra Hoekzema, Evan E. Eichler, Joao V. Nani, Wirla Pontes, Sandra Sanchez Sanchez, Michael V. Lombardo, Janaina S. de Souza, Mirian A. F. Hayashi, Alysson R. Muotri
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Social affective and communication symptoms are central to autism spectrum disorder (ASD), yet their severity differs across toddlers: Some toddlers with ASD display improving abilities across early ages and develop good social an
Externí odkaz:
https://doaj.org/article/428ca825209e4345a0da67a2ab8b0da8
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Adults typically exhibit right hemispheric dominance in the processing of faces. In this cross-sectional study, we investigated age-dependent changes in face processing lateralization from infancy to adulthood (1–48 years old; N = 194). We
Externí odkaz:
https://doaj.org/article/f64d9f37eaad44ed953594f692520d89
Autor:
Yaqiong Xiao, Teresa H. Wen, Lauren Kupis, Lisa T. Eyler, Vani Taluja, Jaden Troxel, Disha Goel, Michael V. Lombardo, Karen Pierce, Eric Courchesne
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Background Social and language abilities are closely intertwined during early typical development. In autism spectrum disorder (ASD), however, deficits in social and language development are early-age core symptoms. We previously reported th
Externí odkaz:
https://doaj.org/article/2c597c894ca948e280f3908996bc93d0
Autor:
Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Joshua D. Bernstock, Shinya Tasaki, Bernard Ng, Chris Gaiteri, Jordan W. Smoller, Tian Ge, Raquel E. Gur, Michael J. Gandal, Aaron F. Alexander-Bloch
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113439- (2023)
Summary: Human brain size changes dynamically through early development, peaks in adolescence, and varies up to 2-fold among adults. However, the molecular genetic underpinnings of interindividual variation in brain size remain unknown. Here, we leve
Externí odkaz:
https://doaj.org/article/64ee1401f7fc44968f6a52b884af8318
Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype
Autor:
Teresa H. Wen, Amanda Cheng, Charlene Andreason, Javad Zahiri, Yaqiong Xiao, Ronghui Xu, Bokan Bao, Eric Courchesne, Cynthia Carter Barnes, Steven J. Arias, Karen Pierce
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Few clinically validated biomarkers of ASD exist which can rapidly, accurately, and objectively identify autism during the first years of life and be used to support optimized treatment outcomes and advances in precision medicine. As such, t
Externí odkaz:
https://doaj.org/article/da8c58902e4d4864a6e8f7333a8f0ddf
Autor:
Benjamin P. Kellman, Hratch M. Baghdassarian, Tiziano Pramparo, Isaac Shamie, Vahid Gazestani, Arjana Begzati, Shangzhong Li, Srinivasa Nalabolu, Sarah Murray, Linda Lopez, Karen Pierce, Eric Courchesne, Nathan E. Lewis
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Both RNA-Seq and sample freeze-thaw are ubiquitous. However, knowledge about the impact of freeze-thaw on downstream analyses is limited. The lack of common quality metrics that are sufficiently sensitive to freeze-thaw and RNA de
Externí odkaz:
https://doaj.org/article/405f1635944c43af9e02eeabec735f15
Autor:
Tianyun Wang, Kendra Hoekzema, Davide Vecchio, Huidan Wu, Arvis Sulovari, Bradley P. Coe, Madelyn A. Gillentine, Amy B. Wilfert, Luis A. Perez-Jurado, Malin Kvarnung, Yoeri Sleyp, Rachel K. Earl, Jill A. Rosenfeld, Madeleine R. Geisheker, Lin Han, Bing Du, Chris Barnett, Elizabeth Thompson, Marie Shaw, Renee Carroll, Kathryn Friend, Rachael Catford, Elizabeth E. Palmer, Xiaobing Zou, Jianjun Ou, Honghui Li, Hui Guo, Jennifer Gerdts, Emanuela Avola, Giuseppe Calabrese, Maurizio Elia, Donatella Greco, Anna Lindstrand, Ann Nordgren, Britt-Marie Anderlid, Geert Vandeweyer, Anke Van Dijck, Nathalie Van der Aa, Brooke McKenna, Miroslava Hancarova, Sarka Bendova, Marketa Havlovicova, Giovanni Malerba, Bernardo Dalla Bernardina, Pierandrea Muglia, Arie van Haeringen, Mariette J. V. Hoffer, Barbara Franke, Gerarda Cappuccio, Martin Delatycki, Paul J. Lockhart, Melanie A. Manning, Pengfei Liu, Ingrid E. Scheffer, Nicola Brunetti-Pierri, Nanda Rommelse, David G. Amaral, Gijs W. E. Santen, Elisabetta Trabetti, Zdeněk Sedláček, Jacob J. Michaelson, Karen Pierce, Eric Courchesne, R. Frank Kooy, The SPARK Consortium, Magnus Nordenskjöld, Corrado Romano, Hilde Peeters, Raphael A. Bernier, Jozef Gecz, Kun Xia, Evan E. Eichler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
For many neurodevelopmental disorder (NDD) risk genes, the significance for mutational burden is unestablished. Here, the authors sequence 125 candidate NDD genes in over 16,000 NDD cases; case-control mutational burden analysis identifies 48 genes w
Externí odkaz:
https://doaj.org/article/e984b4b7e89d4200874d3fcd3c269adc
Autor:
Ritu Thamman, Samantha Streuli, Najla Ibrahim, Alia Mohamed, Manupriya Sharma, Markie Esmailian, Ibrahim Sezan, Carrie Farrell, Mark Sawyer, Dan Meyer, Khaled El-Maleh, Alex Marchetti, Alan Lincoln, Eric Courchesne, Ahmed Sahid, Sanjeev P Bhavnani
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Objectives To combat misinformation, engender trust and increase health literacy, we developed a culturally and linguistically appropriate virtual reality (VR) vaccination education platform using community-engaged approaches within a Somali refugee
Externí odkaz:
https://doaj.org/article/ae4ad31816f442aeb7c90ecf19fae32e