Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Eric, Bacqué"'
Autor:
Landys Lopez Quezada, Sandra Silve, Mark Kelinske, Amir Liba, Constantino Diaz Gonzalez, Martin Kotev, Laurent Goullieux, Stephanie Sans, Christine Roubert, Sophie Lagrange, Eric Bacqué, Cedric Couturier, Alain Pellet, Isabelle Blanc, Marlène Ferron, Fabrice Debu, Kelin Li, Jeffrey Aubé, Julia Roberts, David Little, Yan Ling, Jun Zhang, Ben Gold, Carl Nathan
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT A defining characteristic of treating tuberculosis is the need for prolonged administration of multiple drugs. This may be due in part to subpopulations of slowly replicating or nonreplicating Mycobacterium tuberculosis bacilli exhibiting ph
Externí odkaz:
https://doaj.org/article/36d78fae9ed74d22a77a85998cdfb018
Autor:
Ben Gold, Jun Zhang, Landys Lopez Quezada, Julia Roberts, Yan Ling, Madeleine Wood, Wasima Shinwari, Laurent Goullieux, Christine Roubert, Laurent Fraisse, Eric Bacqué, Sophie Lagrange, Bruno Filoche-Rommé, Michal Vieth, Philip A. Hipskind, Louis N. Jungheim, Jeffrey Aubé, Sarah M. Scarry, Stacey L. McDonald, Kelin Li, Andrew Perkowski, Quyen Nguyen, Véronique Dartois, Matthew Zimmerman, David B. Olsen, Katherine Young, Shilah Bonnett, Douglas Joerss, Tanya Parish, Helena I. Boshoff, Kriti Arora, Clifton E. Barry, Laura Guijarro, Sara Anca, Joaquín Rullas, Beatriz Rodríguez-Salguero, Maria S. Martínez-Martínez, Esther Porras-De Francisco, Monica Cacho, David Barros-Aguirre, Paul Smith, Steven J. Berthel, Carl Nathan, Robert H. Bates
Publikováno v:
ACS Infectious Diseases. 8:557-573
Rising antimicrobial resistance challenges our ability to combat bacterial infections. The problem is acute for tuberculosis (TB), the leading cause of death from infection before COVID-19. Here, we developed a framework for multiple pharmaceutical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fbb240736098b21d77522307cf2134
https://doi.org/10.1021/acsinfecdis.1c00570
https://doi.org/10.1021/acsinfecdis.1c00570
Autor:
Samantha Ottavi, Sarah M. Scarry, John Mosior, Yan Ling, Julia Roberts, Amrita Singh, David Zhang, Laurent Goullieux, Christine Roubert, Eric Bacqué, H. Rachel Lagiakos, Jeremie Vendome, Francesca Moraca, Kelin Li, Andrew J. Perkowski, Remya Ramesh, Matthew M. Bowler, William Tracy, Victoria A. Feher, James C. Sacchettini, Ben S. Gold, Carl F. Nathan, Jeffrey Aubé
Publikováno v:
Journal of Medicinal Chemistry. 65:1996-2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13bb9e5143b62526d09858cde7842507
https://doi.org/10.1021/acs.jmedchem.1c01565
https://doi.org/10.1021/acs.jmedchem.1c01565
Autor:
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi‐Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7665e9de5685b49b9f57896c49828d9b
https://doi.org/10.1002/ange.202210747
https://doi.org/10.1002/ange.202210747
Autor:
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi‐Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard
Publikováno v:
Angewandte Chemie (International ed. in English). 61(51)
Herein, we describe the myxobacterial natural product Corramycin isolated from Corallococcus coralloides. The linear peptide structure contains an unprecedented (2R,3S)-γ-N-methyl-β-hydroxy-histidine moiety. Corramycin exhibits anti-Gram-negative a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf736297578c1c29ac5d3fb1e5eac92d
https://pubmed.ncbi.nlm.nih.gov/36197755
https://pubmed.ncbi.nlm.nih.gov/36197755
Autor:
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi-Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard
Herein, we describe the myxobacterial natural product Corramycin (1) isolated from Corallococcus coralloides (C. coralloides). Corramycin is a linear peptide containing an unprecedented (2R,3S) N-methyl-β-hydroxy histidine moiety and exhibiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13eb3a5080d94905306938faaaa2712b
https://doi.org/10.26434/chemrxiv-2022-97gp2
https://doi.org/10.26434/chemrxiv-2022-97gp2
Autor:
Sylvain Petit, Sören M. M. Schuler, Raffael C. Wende, Daniel N. Wilson, Frédéric Jeannot, Christoph Pöverlein, Cedric Couturier, Armin Bauer, Michael Kurz, Eric Bacqué, Gerrit Jürjens, Fabian Nguyen, Peter Hammann
Publikováno v:
Angewandte Chemie. 130:12334-12338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abab414ec5d40e95353ea48b7169ed0e
https://doi.org/10.1002/ange.201805901
https://doi.org/10.1002/ange.201805901
Autor:
Thomas Germe, Judit Vörös, Frederic Jeannot, Thomas Taillier, Robert A Stavenger, Eric Bacqué, Anthony Maxwell, Benjamin D Bax
Publikováno v:
'Nucleic Acids Research ', vol: 46, pages: 4114-4128 (2018)
Nucleic Acids Research
Nucleic Acids Research
Imidazopyrazinones (IPYs) are a new class of compounds that target bacterial topoisomerases as a basis for their antibacterial activity. We have characterized the mechanism of these compounds through structural/mechanistic studies showing they bind a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b2261fc0c457dde126409167bcaa7d
https://doi.org/10.1093/nar/gky181
https://doi.org/10.1093/nar/gky181
Autor:
Eric Bacqué
Publikováno v:
CHIMIA, Vol 58, Iss 3 (2004)
The influence of a fluorine atom at position C(16) of antibacterial pristinamycins II upon antibacterial, physico-chemical and pharmacokinetics properties is described.
Externí odkaz:
https://doaj.org/article/872cf6e309f04383877ab43ac0e1a1bd
Autor:
Amir Liba, Jeffrey Aubé, Yan Ling, Eric Bacqué, Constantino Diaz Gonzalez, Fabrice Debu, David Little, Kelin Li, Landys Lopez Quezada, Stéphanie Sans, Julia Roberts, Isabelle Le Blanc, Cedric Couturier, Alain Pellet, Sophie Lagrange, Laurent Goullieux, Sandra Silve, Mark Lee Kelinske, Ben Gold, Carl Nathan, Marlène Ferron, Martin Kotev, Christine Roubert, Jun Zhang
Publikováno v:
mBio, Vol 10, Iss 4, p e01405-19 (2019)
mBio, Vol 10, Iss 4 (2019)
mBio
mBio, Vol 10, Iss 4 (2019)
mBio
Antimycobacterial agents might shorten the course of treatment by reducing the number of phenotypically tolerant bacteria if they could kill M. tuberculosis in diverse metabolic states. Here we report two chemically disparate classes of agents that k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96da59e92a39623c932102d71216b3d
https://doaj.org/article/e35ba3238a254970bc348f474dae2e6c
https://doaj.org/article/e35ba3238a254970bc348f474dae2e6c