Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Erhard Severin"'
Autor:
Elke Pascher, Erhard Severin, U. Hacker-Klom, Normann Willich, Burkhard Greve, Niels Wedemeyer, Joachim Kienast, Gerda Silling, Wolfgang Göhde
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 64:242-250
Purpose: An escalation in standard irradiation dose ensuring improved local tumor control is estimated, but this strategy would require the exclusion of the most sensitive individuals from treatment. Therefore, fast and reliable assays for prediction
Autor:
Klaus-Dieter Greif, Erhard Severin, H. J. Brede, W. Köhnlein, D. Schlegel, Wolfgang Göhde, Niels Wedemeyer, D. Uthe
Publikováno v:
International Journal of Radiation Biology. 79:911-918
The shape of the dose-effect curve for neutrons, i.e. the question as to whether the curve is linear or supralinear in the low-dose region, is still not clear. Therefore, the mutagenic effect of very low doses of low-energy neutrons was determined.Hu
Autor:
M. Frankenberg-Schwager, Wolfgang Göhde, E. Pralle, Daniela Uthe, Burkhard Greve, Erhard Severin, D. Frankenberg, I. Garg
Publikováno v:
Journal of Radiological Protection. 22:A17-A20
Mutation induction in the HPRT gene of human fibroblasts after irradiation with mammography-like 29 kVp or 200 kVp x-rays shows radiohypersensitivity for doses smaller than approximately 0.5 Gy. Similarly, mutation induction in the CD 59 gene on huma
Autor:
K. Tapernon, Uwe Cassens, Burkhard Greve, Walter Sibrowski, B. Nave, Wolfgang Göhde, Erhard Severin
Publikováno v:
Vox Sanguinis. 82:198-206
BACKGROUND AND OBJECTIVES Accurate determination of residual leucocytes [white blood cells (WBC)] in blood components is of high clinical importance. To date, several labour-intensive, time-consuming or expensive techniques have been used for this pu
Autor:
I. Garg, Wolfgang Göhde, M. Frankenberg-Schwager, Erhard Severin, Daniela Uthe, Burkhard Greve, D. Frankenberg
Publikováno v:
International Journal of Radiation Biology. 78:781-789
To measure the mutagenic effectiveness of low-filtered 30 kVp X-rays, mammography X-rays and conventional (200 kVp) X-rays in mammalian cells.Two different cell lines and mutation assays were used. Exponentially growing SV40-transformed human fibrobl
Autor:
Erhard Severin, Burkhard Greve, U. Hacker-Klom, Niels Wedemeyer, Wolfgang Köhnlein, Wolfgang Göhde, Daniela Uthe, Dagmar Denklau, Thomas Pötter
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 473:73-84
Determination of the genotoxic effects of ionizing radiation, especially at low-doses, is of great importance for risk assessment, e.g. in radiological diagnostics. The human-hamster hybrid A L cell line has been shown previously to be a well-suited
Autor:
Eberhard Seidler, Erhard Severin
Publikováno v:
Journal of Histochemistry & Cytochemistry. 46:761-765
SUMMARY The tetrazolium salt 5-cyano-2,3-di- p -toluyl-tetrazolium chloride (CTC), yielding a fluorescent formazan on reduction, was used to measure NAD(P)H oxidoreductase activity. In this study, optimal conditions for the flow cytometric technique
Publikováno v:
Physics in medicine and biology. 50(7)
Very thin material layers (100 microm) partially absorb ionizing radiation of low energy. When irradiating monolayer cell cultures from above, attention must be paid to absorption by the medium. Frequently, the volume of the nutrient medium is variab
Autor:
Constanze Beller, Burkhard Greve, Walter Sibrowski, Erhard Severin, Wolfgang Göhde, Uwe Cassens
Publikováno v:
Journal of hematotherapystem cell research. 12(3)
All current-flow cytometric techniques use erythrocyte-lysing procedures before leukocyte analysis. We investigated the impact of four lysing procedures with different flow cytometric techniques on the loss of leukocytes and hematopoietic progenitor
Autor:
Erhard Severin, Che-Jen Huang
Publikováno v:
Acta histochemica. 94(1)
Summary Flow cytometric measurements of the activities of lactate dehydrogenase, glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase, glycerol-3-phosphate dehydrogenase, succinate dehydrogenase and glutamate dehydrogenase in single Ehrlich as