Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Erfðarannsóknir"'
1
A polygenic resilience score moderates the genetic risk for schizophrenia
Autor: Hess, Jonathan L, Tylee, Daniel S, Mors, Ole, Duan, Jubao, Dudbridge, Frank, Duncanson, Audrey, Durmishi, Naser, Edkins, Sarah, Ehrenreich, Hannelore, Eichhammer, Peter, Eriksson, Johan, Escott-Price, Valentina, Esko, Tõnu, Nordentoft, Merete, Essioux, Laurent, Fanous, Ayman H, Farh, Kai-How, Farrell, Martilias S, Frank, Josef, Franke, Lude, Freedman, Robert, Freeman, Colin, Freimer, Nelson B, Friedl, Marion, Hougaard, David M, Friedman, Joseph I, Fromer, Menachem, Gejman, Pablo V, Genovese, Giulio, Georgieva, Lyudmila, Giannoulatou, Eleni, Giegling, Ina, Gill, Michael, Gillman, Matthew, Giusti-Rodríguez, Paola, Byberg-Grauholm, Jonas, Godard, Stephanie, Goldstein, Jacqueline I, Golimbet, Vera, Gopal, Srihari, Gratten, Jacob, Gray, Emma, Gurling, Hugh, Gwilliam, Rhian, de Haan, Lieuwe, Hall, Jeremy, Bækvad-Hansen, Marie, Hammer, Christian, Hammond, Naomi, Hamshere, Marian L, Hansen, Mark, Hansen, Thomas, Haroutunian, Vahram, Hartmann, Annette M, Hellenthal, Garrett, Henskens, Frans A, Herms, Stefan, Greenwood, Tiffany A, Hirschhorn, Joel N, Hoffmann, Per, Hofman, Andrea, Hollegaard, Mads V, Huang, Hailiang, Hultman, Christina M, Hunt, Sarah E, Ikeda, Masashi, Iwata, Nakao, Iyegbe, Conrad, Tsuang, Ming T, Jablensky, Assen V, Jankowski, Janusz, Jayakumar, Alagurevathi, Joa, Inge, Jönsson, Erik G, Julià, Antonio, Kähler, Anna K, Kahn, René S, Kalaydjieva, Luba, Karachanak-Yankova, Sena, Curtis, David, Karjalainen, Juha, Kavanagh, David, Keller, Matthew C, Kendler, Kenneth S, Kennedy, James L, Khrunin, Andrey, Kim, Yunjung, Kirov, George, Klovins, Janis, Knight, Jo, Steinberg, Stacy, Knowles, James A, Konte, Bettina, Kucinskas, Vaidutis, Kucinskiene, Zita Ausrele, Kuzelova-Ptackova, Hana, Langford, Cordelia, Laurent, Claudine, Lawrie, Stephen, Lee, S Hong, Lee, Phil, Sigurdsson, Engilbert, Lee, Jimmy, Legge, Sophie E, Lencz, Todd, Lerer, Bernard, Levinson, Douglas F, Lewis, Cathryn M, Li, Tao, Li, Qingqin S, Li, Miaoxin, Liang, Kung-Yee, Mattheisen, Manuel, Stefánsson, Hreinn, Liddle, Jennifer, Lieberman, Jeffrey, Limborska, Svetlana, Lin, Kuang, Linszen, Don H, Liu, Jianjun, Lönnqvist, Jouko, Loughland, Carmel M, Lubinski, Jan, Macek, Milan, Stefánsson, Kári, Magnusson, Patrik K E, Maher, Brion S, Maier, Wolfgang, Malhotra, Anil K, Mallet, Jacques, Markus, Hugh S, Marsal, Sara, Mata, Ignacio, Mathew, Christopher G, Mattingsdal, Morten, Edenberg, Howard J, McCann, Owen T, McCarley, Robert W, McCarroll, Steven A, McCarthy, Mark I, McDonald, Colm, McIntosh, Andrew M, McQuillin, Andrew, Meier, Sandra, Meijer, Carin J, Melegh, Bela, Holmans, Peter, Melle, Ingrid, Mesholam-Gately, Raquelle I, Metspalu, Andres, Michie, Patricia T, Milani, Lili, Milanova, Vihra, Mokrab, Younes, Moran, Jennifer L, Morris, Derek W, Mowry, Bryan J, Faraone, Stephen V, Müller-Myhsok, Bertram, Murphy, Kieran C, Murray, Robin M, Myin-Germeys, Inez, Neale, Benjamin M, Nelis, Mari, Nenadic, Igor, Nertney, Deborah A, Nestadt, Gerald, Nicodemus, Kristin K, Glatt, Stephen J, Nikitina-Zake, Liene, Nisenbaum, Laura, Nordin, Annelie, Nöthen, Markus M, O'Callaghan, Eadbhard, O'Donovan, Michael C, O'Dushlaine, Colm, O'Neill, F Anthony, Oh, Sang-Yun, Olincy, Ann, Adolfsson, Rolf, Olsen, Line, Ophoff, Roel A, Van Os, Jim, Owen, Michael J, Palmer, Colin N A, Palotie, Aarno, Pantelis, Christos, Papadimitriou, George N, Papiol, Sergi, Parkhomenko, Elena, Agartz, Ingrid, Pato, Michele T, Pato, Carlos N, Paunio, Tiina, Pearson, Richard, Cairns, Murray J, DeLisi, Lynn E, Gershon, Elliot S, Kelly, Brian J, Lam, Max, Norgren, Nina, Agerbo, Esben, Paciga, Sara A, Tooney, Paul A, Wu, Jing Qin, Pejovic-Milovancevic, Milica, Perkins, Diana O, Pers, Tune H, Petryshen, Tracey L, Pietiläinen, Olli, Pimm, Jonathan, Pirinen, Matti, Albus, Margot, Plomin, Robert, Pocklington, Andrew J, Posthuma, Danielle, Potter, Simon C, Powell, John, Price, Alkes, Pulver, Ann E, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Consortium, Schizophrenia Working Group of the Psychiatric Genomics, Alexander, Madeline, Rautanen, Anna, Ravindrarajah, Radhi, Reichenberg, Abraham, Reimers, Mark A, Richards, Alexander L, Ricketts, Michelle, Rietschel, Marcella, Riley, Brien P, Ripke, Stephan, Roffman, Joshua L, Amin, Farooq, Roussos, Panos, Ruderfer, Douglas M, Rujescu, Dan, Salomaa, Veikko, Sanders, Alan R, Sawcer, Stephen J, Schall, Ulrich, Schubert, Christian R, Schulze, Thomas G, Schwab, Sibylle G, Andreassen, Ole A, Scolnick, Edward M, Scott, Rodney J, Seidman, Larry J, Sham, Pak C, Shi, Jianxin, Silagadze, Teimuraz, Silverman, Jeremy M, Sim, Kang, Sklar, Pamela, Arranz, Maria J, Slominsky, Petr, Smoller, Jordan W, So, Hon-Cheong, Söderman, Erik, Spencer, Chris C A, Clair, David St, Stahl, Eli A, Stogmann, Elisabeth, Strange, Amy, Straub, Richard E, Bacanu, Silviu A, Strengman, Eric, Strohmaier, Jana, Stroup, T Scott, Su, Zhan, Subramaniam, Mythily, Sullivan, Patrick F, Suvisaari, Jaana, Svrakic, Dragan M, Szatkiewicz, Jin P, Tashakkori-Ghanbaria, Avazeh, Bakker, Steven, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Trembath, Richard C, Veijola, Juha, Visscher, Peter M, Viswanathan, Ananth C, Vukcevic, Damjan, Waddington, John, Waller, Matthew, Band, Gavin, Walsh, Dermot, Walshe, Muriel, Walters, James T R, Wang, Qiang, Wang, Dai, Webb, Bradley T, Weinberger, Daniel R, Weisbrod, Matthias, Weiser, Mark, Wendland, Jens R, Barroso, Ines, Weston, Paul, Whittaker, Pamela, Widaa, Sara, Wiersma, Durk, Wildenauer, Dieter B, Williams, Stephanie, Williams, Nigel M, Witt, Stephanie H, Wolen, Aaron R, Wong, Emily H M, Begemann, Martin, Wood, Nicholas W, Wormley, Brandon K, Wray, Naomi R, Xi, Hualin Simon, Zai, Clement C, Zheng, Xuebin, Zimprich, Fritz, Bellenguez, Céline, Research, Lundbeck Foundation Initiative for Integrative Psychiatric, Belliveau, Richard A, Bender, Stephan, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Blackburn, Hannah, Blackwell, Jenefer M, Blackwood, Douglas H R, Børglum, Anders D, Bramon, Elvira, Brown, Matthew A, Bruggeman, Richard, Buccola, Nancy G, Buckner, Randy L, Bulik-Sullivan, Brendan, Bumpstead, Suzannah J, Buxbaum, Joseph D, Byerley, William, Cahn, Wiepke, Als, Thomas D, Cai, Guiqing, Campion, Dominique, Cantor, Rita M, Carr, Vaughan J, Carrera, Noa, Casas, Juan P, Catts, Stanley V, Chambert, Kimberley D, Chan, Ronald Y L, Chan, Raymond C K, Grove, Jakob, Chen, Eric Y H, Cheng, Wei, Cheung, Eric F C, Chong, Siow Ann, Cichon, Sven, Cloninger, C Robert, Cohen, David, Cohen, Nadine, Collier, David A, Cormican, Paul, Werge, Thomas, Corvin, Aiden, Craddock, Nick, Crespo-Facorro, Benedicto, Crowley, James J, Daly, Mark J, Darvasi, Ariel, Davidson, Michael, Davis, Kenneth L, Degenhardt, Franziska, Del Favero, Jurgen, Mortensen, Preben Bo, Deloukas, Panos, Demontis, Ditte, Dikeos, Dimitris, Dinan, Timothy, Djurovic, Srdjan, Domenici, Enrico, Donnelly, Peter, Donohoe, Gary, Drapeau, Elodie, Dronov, Serge
Publikováno v: Hess, J L, Tylee, D S, Mattheisen, M, Børglum, A D, Als, T D, Grove, J, Werge, T, Mortensen, P B, Mors, O, Nordentoft, M, Hougaard, D M, Byberg-Grauholm, J, Bækvad-Hansen, M, Greenwood, T A, Tsuang, M T, Curtis, D, Steinberg, S, Sigurdsson, E, Stefánsson, H, Stefánsson, K, Edenberg, H J, Holmans, P, Faraone, S V, Glatt, S J, Schizophrenia Working Group of the Psychiatric Genomics Consortium & Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) 2021, ' A polygenic resilience score moderates the genetic risk for schizophrenia ', Molecular Psychiatry, vol. 26, no. 3, pp. 800-815 . https://doi.org/10.1038/s41380-019-0463-8
Schizophrenia Working Group of the Psychiatric Genomics Consortium 2019, ' A polygenic resilience score moderates the genetic risk for schizophrenia ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0463-8
Molecular psychiatry 26, 800–815 (2021). doi:10.1038/s41380-019-0463-8
Molecular psychiatry
Molecular psychiatry, 26, 800-815. Nature Publishing Group
Hess, J L, Tylee, D S, Mattheisen, M, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A D, Als, T D, Grove, J, Werge, T, Mortensen, P B, Mors, O, Nordentoft, M, Hougaard, D M, Byberg-Grauholm, J, Bækvad-Hansen, M, Greenwood, T A, Tsuang, M T, Curtis, D, Steinberg, S, Sigurdsson, E, Stefánsson, H, Stefánsson, K, Edenberg, H J, Holmans, P, Faraone, S V & Glatt, S J 2021, ' A polygenic resilience score moderates the genetic risk for schizophrenia ', Molecular Psychiatry, vol. 26, no. 3, pp. 800–815 . https://doi.org/10.1038/s41380-019-0463-8
Molecular psychiatry, vol 26, iss 3
Hess, J L, Tylee, D S, Mattheisen, M, The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A D, Als, T D, Grove, J, Werge, T, Mortensen, P B, Mors, O, Nordentoft, M, Hougaard, D M, Byberg-grauholm, J, Bækvad-hansen, M, Greenwood, T A, Tsuang, M T, Curtis, D, Steinberg, S, Sigurdsson, E, Stefánsson, H, Stefánsson, K, Edenberg, H J, Holmans, P, Faraone, S V & Glatt, S J 2021, ' A polygenic resilience score moderates the genetic risk for schizophrenia ', Molecular Psychiatry, vol. 26, pp. 800–815 . https://doi.org/10.1038/s41380-019-0463-8
Molecular Psychiatry, 26(3), 800-815. Nature Publishing Group
Publisher's version (útgefin grein)
Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3471197df8fec836d8bcf93e6e4b37fd
https://research.vu.nl/en/publications/15dcf4e5-af27-45fe-b775-143bf7e22e6b
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3
Brain age prediction using deep learning uncovers associated sequence variants
Autor: Magnus O. Ulfarsson, Gyda Bjornsdottir, Daniel F. Gudbjartsson, G. Bragi Walters, Thorgeir E. Thorgeirsson, Benedikt Atli Jónsson, Kari Stefansson, Lotta Maria Ellingsen, Hreinn Stefansson
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Publisher's version (útgefin grein).
Machine learning algorithms can be trained to estimate age from brain structural MRI. The difference between an individual’s predicted and chronological age, predicted age difference (PAD), is a phenotype
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0dcef62f91ac1cc4200d3b4e71b2e0
http://link.springer.com/article/10.1038/s41467-019-13163-9
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4
GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs
Autor: Hannes P. Eggertsson, Daniel F. Gudbjartsson, Snaedis Kristmundsdottir, Hakon Jonsson, Marteinn T. Hardarson, Kari Stefansson, Bjarni V. Halldorsson, Páll Melsted, Doruk Beyter, Astros Skuladottir
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Nature Communications
Publisher's version (útgefin grein).
Analysis of sequence diversity in the human genome is fundamental for genetic studies. Structural variants (SVs) are frequently omitted in sequence analysis studies, although each has a relatively large impa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44987e09ccbf4c6c1b1bd08fc28c0a83
https://doaj.org/article/cd77ec3f22c54b3da55a42242e739711
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5
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
Autor: Sina A. Gharib, Kenneth Rice, Donna K. Arnett, Tõnu Esko, Annemarie I. Luik, Niki Dimou, Dabeeru C. Rao, Pamela J. Schreiner, Melissa A. Richard, Reedik Mägi, Nicholette D. Palmer, Stefan Weiss, Han Chen, Solomon K. Musani, W. James Gauderman, Christian Gieger, Kari E. North, Salman M. Tajuddin, Diana van Heemst, Rainer Rauramaa, Stephen B. Kritchevsky, Henry Völzke, Minjung Kho, Michele K. Evans, Ruth J. F. Loos, Correa Adolfo, Pedro Marques-Vidal, Diane M. Becker, Claude Bouchard, José Haba-Rubio, Georg Homuth, Kurt Lohman, Nora Franceschini, Caizheng Yu, Peter Vollenweider, Ervin F. Fox, Thomas Meitinger, Karen Schwander, Heming Wang, Morris A. Swertz, Aldi T. Kraja, José Eduardo Krieger, Xiuqing Guo, Tangchun Wu, Raymond Noordam, Yongmei Liu, Michael R. Brown, Patrick C.N. Rensen, Annette Peters, Jingmin Liu, Tuomo Rankinen, Robert B. Wallance, Timo A. Lakka, Stephen S. Rich, Yun Ju Sung, Meian He, Till Roenneberg, Wanqing Wen, Dennis O. Mook-Kanamori, M. A. Province, Evangelos Evangelou, L. Adrienne Cupples, Maxime M Bos, Paul S. de Vries, Hans J. Grabe, Lisa R. Yanek, Jiwon Lee, Mario Sims, Bruce M. Psaty, Treva Rice, Tanika N. Kelly, Brenda W.J.H. Penninx, Brigitte Kühnel, Maria E. Graff, Alexandre C. Pereira, Daniel J. Gottlieb, Charles N. Rotimi, Lynne E. Wagenknecht, Ashley van der Spek, Lisa W. Martin, Jeffrey R. O'Connell, Changwei Li, James E. Hixson, Chuan Gao, Alisa K. Manning, Sharon L.R. Kardia, Stella Aslibekyan, Andres Metspalu, Sami Heikkinen, Maris Alver, Xiao-Ou Shu, Amy R. Bentley, Susan Redline, Konstantin Strauch, Tamara B. Harris, Yuri Milaneschi, L.F. Bielak, Marjan Ilkov, Myriam Fornage, Ilja M. Nolte, André G. Uitterlinden, Dina Vojinovic, Hugues Aschard, Paul Elliott, Kent D. Taylor, Najaf Amin, James M. Shikany, Yong-Bing Xiang, Jerome I. Rotter, Vilmundur Gudnason, Cornelia M. van Duijn, Ko Willems van Dijk, Andrea R. V. R. Horimoto, Jonathan Marten, Olli T. Raitakari, Vincent Laville, Pirjo Komulainen, Zhe Wang, Traci M. Bartz, Mary F. Feitosa, Mike A. Nalls, Eric Boerwinkle, Alanna C. Morrison, Melanie Waldenberger, Alexander P. Reiner, Christie M. Ballantyne, Wei Zheng, Raphael Heinzer, M. Arfan Ikram, Colleen M. Sitlani, Lisa de las Fuentes, Patricia B. Munroe, Patricia A. Peyser, Brian E. Cade, Tamar Sofer, Xiaofeng Zhu, Nienke R. Biermasz, Harold Snieder, Elise Lim, Tuomas O. Kilpeläinen, Ching-Ti Liu, Terho Lehtimäki, Thomas W. Winkler, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Stephen Sidney, Alan B. Zonderman, Charles Kooperberg
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group UK
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X O, Snieder, H, Weiss, S & Penninx, B W J H 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de Las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L-P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X-O, Snieder, H, Weiss, S, Wen, W, Yanek, L R, Adolfo, C, Ballantyne, C, Bielak, L, Biermasz, N R, Boerwinkle, E, Dimou, N, Eiriksdottir, G, Gao, C, Gharib, S A, Gottlieb, D J, Haba-Rubio, J, Harris, T B, Heikkinen, S, Heinzer, R, Hixson, J E, Homuth, G, Ikram, M A, Komulainen, P, Krieger, J E, Lee, J, Liu, J, Lohman, K K, Luik, A I, Mägi, R, Martin, L W, Meitinger, T, Metspalu, A, Milaneschi, Y, Nalls, M A, O'Connell, J, Peters, A, Peyser, P, Raitakari, O T, Reiner, A P, Rensen, P C N, Rice, T K, Rich, S S, Roenneberg, T, Rotter, J I, Schreiner, P J, Shikany, J, Sidney, S S, Sims, M, Sitlani, C M, Sofer, T, Strauch, K, Swertz, M A, Taylor, K D, Uitterlinden, A G, van Duijn, C M, Völzke, H, Waldenberger, M, Wallance, R B, van Dijk, K W, Yu, C, Zonderman, A B, Becker, D M, Elliott, P, Esko, T, Gieger, C, Grabe, H J, Lakka, T A, Lehtimäki, T, North, K E, Penninx, B W J H, Vollenweider, P, Wagenknecht, L E, Wu, T, Xiang, Y-B, Zheng, W, Arnett, D K, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S, Kelly, T N, Kritchevsky, S B, Loos, R J F, Pereira, A C, Province, M, Psaty, B M, Rotimi, C, Zhu, X, Amin, N, Cupples, L A, Fornage, M, Fox, E F, Guo, X, Gauderman, W J, Rice, K, Kooperberg, C, Munroe, P B, Liu, C-T, Morrison, A C, Rao, D C, van Heemst, D & Redline, S 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature communications, vol. 10, no. 1, pp. 5121
Publisher's version (útgefin grein).
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b5fb699bc64fdb1c35600118d5f0de
https://doaj.org/article/7a287494756c4fbcb7eb0688fb50e01b
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6
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
Autor: Cindy G. Boer, Timothy Kwok, Kristbjorg Gunnarsdottir, Tuan V. Nguyen, Jenny S.W. Lee, Seung-Hun Lee, Stefania Benonisdottir, Helgi Jonsson, Gunnar Sigurdsson, Unnur Styrkarsdottir, Kristinn Juliusson, Gudmundur L. Norddahl, Lan T. Ho-Pham, Jung Min Koh, Inger Byrjalsen, Daniel F. Gudbjartsson, Lilja Stefansdottir, Claus Christiansen, Unnur Thorsteinsdottir, Jason Leung, Thorvaldur Ingvarsson, Brynjolfur Mogensen, Eleftheria Zeggini, Olafur A. Stefansson, John Loughlin, Gisli Masson, Kari Stefansson, Arnaldur Gylfason, Lorraine Southam, Arna B Agustsdottir, Rafn Benediktsson, Fernando Rivadeneira, Gisli H. Halldorsson, Suzanne C. Ho, Hilma Holm, Katerina Trajanoska, Hakon Jonsson, Sigrun H. Lund, Joyce B. J. van Meurs, Florian Zink, Kristjan Norland, Nelson L.S. Tang, L. Stefan Lohmander, Erna V. Ivarsdottir, Gudmar Thorleifsson, Ingileif Jonsdottir, P. C. Leung, André G. Uitterlinden, John A. Eisman, Jean Woo, Patrick Sulem
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 10:Unsp 2054. Nature Publishing Group
Nat. Commun. 10:2054 (2019)
Publisher's version (útgefin grein).
Bone area is one measure of bone size that is easily derived from dual-energy X-ray absorptiometry (DXA) scans. In a GWA study of DXA bone area of the hip and lumbar spine (N ≥ 28,954), we find thirteen in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d1b8483841a84752c8852f16a161d0
https://doaj.org/article/80e678269bfd4ce6a62646dd799db50a
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7
MITF and TFEB cross-regulation in melanoma cells
Autor: Lionel Larue, Eiríkur Steingrímsson, Valerie Fock, Ramile Dilshat, Katrin Möller, Margret H. Ogmundsdottir, Ludwig Karl, Josué Ballesteros-Álvarez
Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238546 (2020)
Publisher's version (útgefin grein)
The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to the basic helix-loop-helix family of leucine zipper transcription factors. MITF is crucial for melanocyte development and differentiation, and has be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6b41148a6e8c302e85ef61a3a8c248
http://europepmc.org/articles/PMC7470386
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8
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
Autor: Guo, Yanjun, Rist, Pamela M., Daghlas, Iyas, Giulianini, Franco, Gormley, Padhraig, Anttila, Verneri, Winsvold, Bendik S., Palta, Priit, Esko, Tonu, Pers, Tune H., Farh, Kai How, Cuenca-Leon, Ester, Muona, Mikko, Furlotte, Nicholas A., Kurth, Tobias, Ingason, Andres, McMahon, George, Ligthart, Lannie, Terwindt, Gisela M., Kallela, Mikko, Freilinger, Tobias M., Ran, Caroline, Gordon, Scott G., Stam, Anine H., Steinberg, Stacy, Borck, Guntram, Koiranen, Markku, Quaye, Lydia, Adams, Hieab H.H., Lehtimäki, Terho, Sarin, Antti Pekka, Wedenoja, Juho, Hinds, David A., Buring, Julie E., Schürks, Markus, Ridker, Paul M., Hrafnsdottir, Maria Gudlaug, Stefansson, Hreinn, Ring, Susan M., Hottenga, Jouke Jan, Penninx, Brenda W.J.H., Färkkilä, Markus, Artto, Ville, Kaunisto, Mari, Vepsäläinen, Salli, Malik, Rainer, Heath, Andrew C., Madden, Pamela A.F., Martin, Nicholas G., Montgomery, Grant W., Kurki, Mitja, Kals, Mart, Mägi, Reedik, Pärn, Kalle, Hämäläinen, Eija, Huang, Hailiang, Byrnes, Andrea E., Franke, Lude, Huang, Jie, Stergiakouli, Evie, Lee, Phil H., Sandor, Cynthia, Webber, Caleb, Cader, Zameel, Muller-Myhsok, Bertram, Schreiber, Stefan, Meitinger, Thomas, Eriksson, Johan G., Salomaa, Veikko, Heikkilä, Kauko, Loehrer, Elizabeth, Uitterlinden, Andre G., Hofman, Albert, Duijn, Cornelia M.van, Cherkas, Lynn, Pedersen, Linda M., Stubhaug, Audun, Nielsen, Christopher S., Männikkö, Minna, Mihailov, Evelin, Milani, Lili, Göbel, Hartmut, Esserlind, Ann Louise, Christensen, Anne Francke, Hansen, Thomas Folkmann, Werge, Thomas, Kaprio, Jaakko, Aromaa, Arpo J., Raitakari, Olli, Ikram, M. Arfan, Spector, Tim, Järvelin, Marjo Riitta, Metspalu, Andres, Kubisch, Christian, Strachan, David P., Ferrari, Michel D., Belin, Andrea C., Dichgans, Martin, Wessman, Maija, Maagdenberg, Arn M.J.M.van den, Zwart, John Anker, Boomsma, Dorret I., Smith, George Davey, Stefansson, Kari, Eriksson, Nicholas, Daly, Mark J., Neale, Benjamin M., Olesen, Jes, Chasman, Daniel I., Nyholt, Dale R., Palotie, Aarno, Agee, Michelle, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H., Mountain, Joanna L., Noblin, Elizabeth S., Northover, Carrie A.M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Vacic, Vladimir
Publikováno v: Nat. Commun. 11:3368 (2020)
Nature Communications, 11(1):3368. Nature Publishing Group UK
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Guo, Y, Rist, P M, Daghlas, I, Giulianini, F, Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Christensen, A F, Hansen, T F, Werge, T, Olesen, J, The International Headache Genetics Consortium & the 23andMe Research Team 2020, ' A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine ', Nature Communications, vol. 11, no. 1, 3368 . https://doi.org/10.1038/s41467-020-17002-0
Guo, Y, Rist, P M, Daghlas, I, Giulianini, F, Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M, Kals, M, Mägi, R, Pärn, K, Hämäläinen, E, Huang, H, Byrnes, A E, Franke, L, Huang, J, Stergiakouli, E, Lee, P H, Sandor, C, Webber, C, Cader, Z, Muller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, J G, Salomaa, V, Heikkilä, K, Loehrer, E, Uitterlinden, A G, Hofman, A, Duijn, C M V, Cherkas, L, Pedersen, L M, Stubhaug, A, Nielsen, C S, Männikkö, M, Mihailov, E, Milani, L, Göbel, H, Esserlind, A L, Christensen, A F, Hansen, T F, Werge, T, Kaprio, J, Aromaa, A J, Raitakari, O, Ikram, M A, Spector, T, Järvelin, M R, Metspalu, A, Kubisch, C, Strachan, D P, Ferrari, M D, Belin, A C, Dichgans, M, Wessman, M, Maagdenberg, A M J M V D, Zwart, J A, Boomsma, D I, Smith, G D, Stefansson, K, Eriksson, N, Daly, M J, Neale, B M, Olesen, J, Chasman, D I, Nyholt, D R, Palotie, A, Agee, M, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, Hinds, D A, Huber, K E, Kleinman, A, Litterman, N K, McCreight, J C, McIntyre, M H, Mountain, J L, Noblin, E S, Northover, C A M, Pitts, S J, Sathirapongsasuti, J F, Sazonova, O V, Shelton, J F, Shringarpure, S, Tian, C, Tung, J Y, Vacic, V, Kurth, T, Chasman, D I, The International Headache Genetics Consortium & the 23andMe Research Team 2020, ' A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine ', Nature Communications, vol. 11, no. 1, 3368 . https://doi.org/10.1038/s41467-020-17002-0
Nature Communications, 11(1):3368, 1-11. Nature Publishing Group
Nature communications
Guo, Y, Ligthart, L, Hottenga, J J, Penninx, B W J H, Boomsma, D I, Chasman, D I, The International Headache Genetics Consortium & The 23andMe Research Team 2020, ' A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine ', Nature Communications, vol. 11, no. 1, 3368, pp. 1-11 . https://doi.org/10.1038/s41467-020-17002-0
Nature Communications
Publisher's version (útgefin grein)
Blood pressure (BP) was inconsistently associated with migraine and the mechanisms of BP-lowering medications in migraine prophylaxis are unknown. Leveraging large-scale summary statistics for migraine (Ncase
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bdfe457fede013ed23e57873fc1ee4
https://hdl.handle.net/20.500.11815/2140
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9
Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease
Autor: Daniel F. Gudbjartsson, Vinicius Tragante, Einar Bjornsson, Alex Hørby Christensen, Erik Sørensen, Ole Birger Pedersen, Solveig Gretarsdottir, Folkert W. Asselbergs, Eythór Björnsson, Søren Brunak, Mette Nyegaard, Olof Sigurdardottir, Ingileif Jonsdottir, Lars Køber, Thomas Hansen, Kari Stefansson, Gardar Sveinbjornsson, Bjorn L. Thorarinsson, Ragnar Danielsen, Gudmundur Thorgeirsson, Brynjar O. Jensson, David O Arnar, Gudmundur I. Eyjolfssson, Stefan E Matthiasson, Henrik Ullum, Valgerdur Steinthorsdottir, Olafur Th Magnusson, Kristjan F. Alexandersson, Hilma Holm, Thora Steingrimsdottir, Christian Erikstrup, Hreinn Stefansson, Anna Helgadottir, Patrick Sulem, Henning Bundgaard, Isleifur Olafsson, Christian Torp-Pedersen, Finnur F. Eiriksson, Karina Banasik, Margret Thorsteinsdottir, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Egil Ferkingstad
Publikováno v: Helgadottir, A, Thorleifsson, G, Alexandersson, K F, Tragante, V, Thorsteinsdottir, M, Eiriksson, F F, Gretarsdottir, S, Björnsson, E, Magnusson, O, Sveinbjornsson, G, Jonsdottir, I, Steinthorsdottir, V, Ferkingstad, E, Jensson, B Ö, Stefansson, H, Olafsson, I, Christensen, A H, Torp-Pedersen, C, Køber, L, Pedersen, O B, Erikstrup, C, Sørensen, E, Brunak, S, Banasik, K, Hansen, T F, Nyegaard, M, Eyjolfssson, G I, Sigurdardottir, O, Thorarinsson, B L, Matthiasson, S E, Steingrimsdottir, T, Bjornsson, E S, Danielsen, R, Asselbergs, F W, Arnar, D O, Ullum, H, Bundgaard, H, Sulem, P, Thorsteinsdottir, U, Thorgeirsson, G, Holm, H, Gudbjartsson, D F & Stefansson, K 2020, ' Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease ', European Heart Journal, vol. 41, no. 28, pp. 2618-2628 . https://doi.org/10.1093/eurheartj/ehaa531
European Heart Journal
Publisher's version (útgefin grein)
Aims: To explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c8fc9df3be04d0aeb2769b55e9263d
https://pure.au.dk/portal/da/publications/genetic-variability-in-the-absorption-of-dietary-sterols-affects-the-risk-of-coronary-artery-disease(6a65941d-531b-409c-b396-d5ed5688737e).html
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