Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Erez Yirmiya"'
Autor:
Izhak Levi, Michael Gurevich, Gal Perlman, David Magalashvili, Shay Menascu, Noam Bar, Anastasia Godneva, Liron Zahavi, Danyel Chermon, Noa Kosower, Bat Chen Wolf, Gal Malka, Maya Lotan-Pompan, Adina Weinberger, Erez Yirmiya, Daphna Rothschild, Sigal Leviatan, Avishag Tsur, Maria Didkin, Sapir Dreyer, Hen Eizikovitz, Yamit Titngi, Sue Mayost, Polina Sonis, Mark Dolev, Yael Stern, Anat Achiron, Eran Segal
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 4, Pp 100246- (2021)
Summary: Multiple sclerosis (MS) is an immune-mediated disease whose precise etiology is unknown. Several studies found alterations in the microbiome of individuals with MS, but the mechanism by which it may affect MS is poorly understood. Here we an
Externí odkaz:
https://doaj.org/article/b32a14cea7e14c03b0afd6f20be716d5
Autor:
Azita Leavitt, Erez Yirmiya, Gil Amitai, Allen Lu, Jeremy Garb, Ehud Herbst, Benjamin R. Morehouse, Samuel J. Hobbs, Sadie P. Antine, Zhen-Yu J. Sun, Philip J. Kranzusch, Rotem Sorek
Publikováno v:
Nature. 611:326-331
Autor:
Erez Yirmiya, Azita Leavitt, Allen Lu, Carmel Avraham, Ilya Osterman, Jeremy Garb, Sadie P. Antine, Sarah E. Mooney, Sam J. Hobbs, Philip J. Kranzusch, Gil Amitai, Rotem Sorek
It was recently shown that bacteria employ, apart from CRISPR-Cas and restriction systems, a considerable diversity of phage resistance systems, but it is largely unknown how phages cope with this multilayered bacterial immunity. Here, we analyzed gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e80b9f023d7e4b2355907961fae8ec73
https://doi.org/10.1101/2023.05.01.538930
https://doi.org/10.1101/2023.05.01.538930
Autor:
Samuel J. Hobbs, Tanita Wein, Allen Lu, Benjamin R. Morehouse, Julia Schnabel, Azita Leavitt, Erez Yirmiya, Rotem Sorek, Philip J. Kranzusch
Publikováno v:
Nature. 605:522-526
The cyclic oligonucleotide-based antiphage signalling system (CBASS) and the pyrimidine cyclase system for antiphage resistance (Pycsar) are antiphage defence systems in diverse bacteria that use cyclic nucleotide signals to induce cell death and pre
Autor:
Yaara Oppenheimer-Shaanan, Tanita Wein, Megan L. Mayer, Erez Yirmiya, Alex G. Johnson, Rotem Sorek, Philip J. Kranzusch, Brianna Duncan-Lowey, Gil Amitai
Publikováno v:
Science
Gasdermin proteins form large membrane pores in human cells that release immune cytokines and induce lytic cell death. Gasdermin pore formation is triggered by caspase-mediated cleavage during inflammasome signaling and is critical for defense agains
Autor:
Francois Rousset, Erez Yirmiya, Shahar Nesher, Alexander Brandis, Tevie Mehlman, Maxim Itkin, Sergey Malitsky, Adi Millman, Sarah Melamed, Rotem Sorek
SummaryDuring viral infection, cells can deploy immune strategies that deprive viruses of molecules essential for their replication. In this study, we report a family of immune effectors in bacteria which, in response to phage infection, degrade cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69114cf8e4968d06e7faa16538f37b9
https://doi.org/10.1101/2023.01.24.525353
https://doi.org/10.1101/2023.01.24.525353
Autor:
Nitzan Tal, Adi Millman, Avigail Stokar-Avihail, Taya Fedorenko, Azita Leavitt, Sarah Melamed, Erez Yirmiya, Carmel Avraham, Alexander Brandis, Tevie Mehlman, Gil Amitai, Rotem Sorek
Publikováno v:
Nature microbiology. 7(8)
DNA viruses and retroviruses consume large quantities of deoxynucleotides (dNTPs) when replicating. The human antiviral factor SAMHD1 takes advantage of this vulnerability in the viral lifecycle, and inhibits viral replication by degrading dNTPs into
Autor:
C. Abraham, Gil Amitai, Adi Millman, Avigail Stokar-Avihail, Taya Fedorenko, Rotem Sorek, Nitzan Tal, Sarah Melamed, Erez Yirmiya, Azita Leavitt
DNA viruses and retroviruses need to consume large quantities of deoxynucleotides (dNTPs) when replicating within infected cells. The human antiviral factor SAMHD1 takes advantage of this vulnerability in the viral life cycle, and inhibits viral repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a432663aacd2e99ced90034408ec36
https://doi.org/10.1101/2021.04.26.441389
https://doi.org/10.1101/2021.04.26.441389
Autor:
Alexander F.A. Keszei, Carmel Avraham, Tevie Mehlman, B.R. Morehouse, Avigail Stokar-Avihail, Sichen Shao, Taya Fedorenko, Erez Yirmiya, Adi Millman, Rotem Sorek, Yaara Oppenheimer-Shaanan, Philip J. Kranzusch, Gil Amitai, Nitzan Tal, Alexander Brandis, Ehud Herbst
Publikováno v:
Cell
The cyclic pyrimidines 3',5'-cyclic cytidine monophosphate (cCMP) and 3',5'-cyclic uridine monophosphate (cUMP) have been reported in multiple organisms and cell types. As opposed to the cyclic nucleotides 3',5'-cyclic adenosine monophosphate (cAMP)