Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Erez Lieberman Aiden"'
Autor:
Michelle Huang, Sarah Kingan, Douglas Shoue, Oanh Nguyen, Lutz Froenicke, Brendan Galvin, Christine Lambert, Ruqayya Khan, Chirag Maheshwari, David Weisz, Gareth Maslen, Helen Davison, Erez Lieberman Aiden, Jonas Korlach, Olga Dudchenko, Mary Ann McDowell, Stephen Richards
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-8 (2024)
Abstract Phlebotomine sand flies are the vectors of leishmaniasis, a neglected tropical disease. High-quality reference genomes are an important tool for understanding the biology and eco-evolutionary dynamics underpinning disease epidemiology. Previ
Externí odkaz:
https://doaj.org/article/ba4febc13c8642608ddf3f0102c33039
Autor:
Emily M. Pujadas Liwag, Xiaolong Wei, Nicolas Acosta, Lucas M. Carter, Jiekun Yang, Luay M. Almassalha, Surbhi Jain, Ali Daneshkhah, Suhas S. P. Rao, Fidan Seker-Polat, Kyle L. MacQuarrie, Joe Ibarra, Vasundhara Agrawal, Erez Lieberman Aiden, Masato T. Kanemaki, Vadim Backman, Mazhar Adli
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-42 (2024)
Abstract Background B-type lamins are critical nuclear envelope proteins that interact with the three-dimensional genomic architecture. However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joi
Externí odkaz:
https://doaj.org/article/4305f5fcf633415aacff6d99aeabee41
Autor:
Hannah L. Harris, Huiya Gu, Moshe Olshansky, Ailun Wang, Irene Farabella, Yossi Eliaz, Achyuth Kalluchi, Akshay Krishna, Mozes Jacobs, Gesine Cauer, Melanie Pham, Suhas S. P. Rao, Olga Dudchenko, Arina Omer, Kiana Mohajeri, Sungjae Kim, Michael H. Nichols, Eric S. Davis, Dimos Gkountaroulis, Devika Udupa, Aviva Presser Aiden, Victor G. Corces, Douglas H. Phanstiel, William Stafford Noble, Guy Nir, Michele Di Pierro, Jeong-Sun Seo, Michael E. Talkowski, Erez Lieberman Aiden, M. Jordan Rowley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Nuclear compartments are prominent features of 3D chromatin organization, but sequencing depth limitations have impeded investigation at ultra fine-scale. CTCF loops are generally studied at a finer scale, but the impact of looping on proxim
Externí odkaz:
https://doaj.org/article/273c83ceac55444f8d76b4044e6d0017
Autor:
Shamshad Ul Hassan, Eng Guan Chua, Erwin A. Paz, Chin Yen Tay, Johan C. Greeff, Dieter G. Palmer, Olga Dudchenko, Erez Lieberman Aiden, Graeme B. Martin, Parwinder Kaur
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Gastrointestinal (GIT) helminthiasis is a global problem that affects livestock health, especially in small ruminants. One of the major helminth parasites of sheep and goats, Teladorsagia circumcincta, infects the abomasum and cau
Externí odkaz:
https://doaj.org/article/fa9b1737b9834ae28a37b852619ea8d2
Autor:
Vinícius G. Contessoto, Olga Dudchenko, Erez Lieberman Aiden, Peter G. Wolynes, José N. Onuchic, Michele Di Pierro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Within the nucleus, the genome of eukaryotes folds into partially organized three-dimensional structures specific to each organism. Here the authors perform physical simulations to study the genome architecture of Aedes aegypti, which reveal an ensem
Externí odkaz:
https://doaj.org/article/4fc89a1f7ff54765accd8077aab1f76b
Autor:
Aki K. Braceros, Megan D. Schertzer, Arina Omer, Jackson B. Trotman, Eric S. Davis, Jill M. Dowen, Douglas H. Phanstiel, Erez Lieberman Aiden, J. Mauro Calabrese
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112803- (2023)
Summary: During mouse embryogenesis, expression of the long non-coding RNA (lncRNA) Airn leads to gene repression and recruitment of Polycomb repressive complexes (PRCs) to varying extents over a 15-Mb domain. The mechanisms remain unclear. Using hig
Externí odkaz:
https://doaj.org/article/a662b708f3d1487695b89dec71f24f05
Autor:
Per A Adastra, Neva C Durand, Namita Mitra, Saul Godinez Pulido, Ragini Mahajan, Alyssa Blackburn, Zane L Colaric, Joshua W M Theisen, David Weisz, Olga Dudchenko, Andreas Gnirke, Suhas S P Rao, Parwinder Kaur, Erez Lieberman Aiden, Aviva Presser Aiden
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294283 (2023)
Early detection of SARS-CoV-2 infection is key to managing the current global pandemic, as evidence shows the virus is most contagious on or before symptom onset. Here, we introduce a low-cost, high-throughput method for diagnosing and studying SARS-
Externí odkaz:
https://doaj.org/article/f33823f08f79457193cd8c50c663b241
Autor:
Tomáš Brůna, Rishi Aryal, Olga Dudchenko, Daniel James Sargent, Daniel Mead, Matteo Buti, Andrea Cavallini, Timo Hytönen, Javier Andrés, Melanie Pham, David Weisz, Flavia Mascagni, Gabriele Usai, Lucia Natali, Nahla Bassil, Gina E Fernandez, Alexandre Lomsadze, Mitchell Armour, Bode Olukolu, Thomas Poorten, Caitlin Britton, Jahn Davik, Hamid Ashrafi, Erez Lieberman Aiden, Mark Borodovsky, Margaret Worthington
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 13, Iss 2 (2022)
AbstractBlackberries (RubusRubusIdaeobatusR. occidentalisR. idaeusR. chingiiRubusR. argutusR. chingiiRubus
Externí odkaz:
https://doaj.org/article/64445879d48e4e108e4672bcde2d5ebd
Autor:
Richard J. Edwards, Matt A. Field, James M. Ferguson, Olga Dudchenko, Jens Keilwagen, Benjamin D. Rosen, Gary S. Johnson, Edward S. Rice, La Deanna Hillier, Jillian M. Hammond, Samuel G. Towarnicki, Arina Omer, Ruqayya Khan, Ksenia Skvortsova, Ozren Bogdanovic, Robert A. Zammit, Erez Lieberman Aiden, Wesley C. Warren, J. William O. Ballard
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background Basenjis are considered an ancient dog breed of central African origins that still live and hunt with tribesmen in the African Congo. Nicknamed the barkless dog, Basenjis possess unique phylogeny, geographical origins and traits,
Externí odkaz:
https://doaj.org/article/6ff5d0c6b0d648a3a470a79f1540a8d8
Autor:
Anjali Kaushal, Giriram Mohana, Julien Dorier, Isa Özdemir, Arina Omer, Pascal Cousin, Anastasiia Semenova, Michael Taschner, Oleksandr Dergai, Flavia Marzetta, Christian Iseli, Yossi Eliaz, David Weisz, Muhammad Saad Shamim, Nicolas Guex, Erez Lieberman Aiden, Maria Cristina Gambetta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Although the Drosophila genome has widespread contact domains and CTCF, it remains unclear whether CTCF-dependent domains exist in flies. Here, the authors ablate CTCF in Drosophila and find that CTCF is required to form a small fraction of all domai
Externí odkaz:
https://doaj.org/article/53617b4d9398422ba368c6a80e44f9a5