Zobrazeno 1 - 10 of 61 pro vyhledávání: '"Ercan, Cacan"'
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NLRP13 inflammasome complex is hypermethylated in familial Mediterranean fever and global methylation correlates with the disease severity
Autor: Feyzanur Yildirimtepe Caldiran, Koksal Deveci, Ercan Cacan
Publikováno v: Annals of Human Genetics. 87:115-124
Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by variations in the MEFV gene, which encodes the pyrin protein, a member of the inflammasomes. Despite the complex pathogenesis of FMF, epigenetic changes also play roles in th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42248f1dc96c3e66272508ec07b20f7d
https://doi.org/10.1111/ahg.12493
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3
Epithelial tumor compartment- and adjacent stromal compartment-specific expression of PARP1 in different anatomical sites in patients with HGSOC
Autor: Ercan Cacan, CAGLAR BERKEL
Publikováno v: Genome Instability & Disease. 3:201-208
High-grade serous ovarian carcinoma (HGSOC) is responsible for the majority of ovarian cancer-associated deaths. PARP (Poly-(ADP-ribose) polymerase) inhibitors (PARPi) (olaparib, rucaparib and niraparib) have been approved in recent years to be used
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084094941a3b988f6b454335207f60c0
https://doi.org/10.1007/s42764-022-00075-0
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4
The expression of GALNT7, a glycosyltransferase, shows estrogen receptor (ER)-, progesterone receptor (PR)- and HER2-dependent changes in breast cancer with implications in prognosis
Autor: CAGLAR BERKEL, ERCAN CACAN
GALNT7 is a glycosyltransferase enzyme transferring N-acetylgalactosamine to initiate O-linked glycosylation in the Golgi apparatus. Breast cancer is the most common cancer in women globally. Estrogen receptor (ER), progesterone receptor (PR), and hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4f6b2d1e33b198bc2b04c7aa4a5eca8
https://doi.org/10.21203/rs.3.rs-2775257/v1
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7
Akademický článek
Combination Treatment with Sublethal Ionizing Radiation and the Proteasome Inhibitor, Bortezomib, Enhances Death-Receptor Mediated Apoptosis and Anti-Tumor Immune Attack
Autor: Ercan Cacan, Alexander M. Spring, Anita Kumari, Susanna F. Greer, Charlie Garnett-Benson
Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 30405-30421 (2015)
Sub-lethal doses of radiation can modulate gene expression, making tumor cells more susceptible to T-cell-mediated immune attack. Proteasome inhibitors demonstrate broad anti-tumor activity in clinical and pre-clinical cancer models. Here, we use a c
Externí odkaz: https://doaj.org/article/9a5113120cfd431e8bdd20eed341113d
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8
Promoter hypomethylation upregulates ANXA2 expression in pancreatic cancer and is associated with poor prognosis
Autor: Soumaya MENADI, Ercan CACAN
Pancreatic cancer (PC) is one of the world's most aggressive and deadly cancers, owing to non-specific early clinical symptoms, late-stage diagnosis, and poor survival. Therefore, it is critical to identify specific biomarkers for its early diagnosis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::137579b3efa6bd55472ff79473ef21c4
https://doi.org/10.21203/rs.3.rs-2306538/v1
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10
The influence of the host sex on infection intensities of parasite lineages belonging to Haemoproteus majoris in a natural bird community
Autor: Caglar Berkel, Ercan Cacan
Immunological capability shows a sexual dimorphism in diverse animal species. Females are generally more immunocompetent than males, leading to the higher susceptibility of males to infection compared to females and thus greater infection-related pat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8260cf3425d326d0d040a7b57ea20a4
https://doi.org/10.21203/rs.3.rs-2020407/v1
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