Design of a Helical-Stabilized, Cyclic, and Nontoxic Analogue of the Peptide Cm-p5 with Improved Antifungal Activity

Autor: Fidel E. Morales Vicente, Melaine González-Garcia, Erbio Diaz Pico, Elena Moreno-Castillo, Hilda E. Garay, Pablo E. Rosi, Asiel Mena Jimenez, Jose A. Campos-Delgado, Daniel G. Rivera, Glay Chinea, Rosemeire C. L. R. Pietro, Steffen Stenger, Barbara Spellerberg, Dennis Kubiczek, Nicholas Bodenberger, Steffen Dietz, Frank Rosenau, Márcio Weber Paixão, Ludger Ständker, Anselmo J. Otero-González

Publikováno v: ACS Omega, Vol 4, Iss 21, Pp 19081-19095 (2019)

Externí odkaz: https://doaj.org/article/b6b61c13663645a58e25f2f09186234b

Antimicrobial activity of cyclic-monomeric and dimeric derivatives of the snail-derived peptide Cm-p5 against viral and multidrug-resistant bacterial strains

Autor: Steffen Stenger, Jan Münch, Janis A. Müller, Rüdiger Groß, Caterina Prelli Bozzo, Heinz Fabian Raber, Carina Conzelmann, Mark Grieshober, Armando A. Rodríguez Alfonso, Fabian Zech, Frank Rosenau, Octavio L. Franco, Alexander N. Zelikin, Hilda Garay, Daniel G. Rivera, Lia Raluca Olari, Fidel Morales-Vicente, Erbio Diaz Pico, Franziska Krüger, Melaine González-García, Dennis Kubiczek, Ludger Ständker, Barbara Spellerberg, Anselmo J. Otero-González

Publikováno v: Biomolecules
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 745, p 745 (2021)
González-García, M, Morales-Vicente, F, Pico, E D, Garay, H, Rivera, D G, Grieshober, M, Olari, L R, Groß, R, Conzelmann, C, Krüger, F, Zech, F, Bozzo, C P, Müller, J A, Zelikin, A, Raber, H, Kubiczek, D, Rosenau, F, Münch, J, Stenger, S, Spellerberg, B, Franco, O L, Alfonso, A A R, Ständker, L & Otero-Gonzalez, A J 2021, ' Antimicrobial activity of cyclic-monomeric and dimeric derivatives of the snail-derived peptide cm-p5 against viral and multidrug-resistant bacterial strains ', Biomolecules, vol. 11, no. 5, 745 . https://doi.org/10.3390/biom11050745

Cm-p5 is a snail-derived antimicrobial peptide, which demonstrated antifungal activity against the pathogenic strains of Candida albicans. Previously we synthetized a cyclic monomer as well as a parallel and an antiparallel dimer of Cm-p5 with improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8955afd4d447d22b6793d0b1e0087484