Associations between baseline characteristics, CD4 cell count response and virological failure on first-line efavirenz + tenofovir + emtricitabine for HIV

Autor: Oliver T. Stirrup, Caroline A. Sabin, Andrew N. Phillips, Ian Williams, Duncan Churchill, Anna Tostevin, Teresa Hill, David T. Dunn, David Asboe, Anton Pozniak, Patricia Cane, David Chadwick, Duncan Clark, Simon Collins, Valerie Delpech, Samuel Douthwaite, David Dunn, Esther Fearnhill, Kholoud Porter, Oliver Stirrup, Christophe Fraser, Anna Maria Geretti, Rory Gunson, Antony Hale, Stéphane Hué, Linda Lazarus, Andrew Leigh-Brown, Tamyo Mbisa, Nicola Mackie, Chloe Orkin, Eleni Nastouli, Deenan Pillay, Andrew Phillips, Caroline Sabin, Erasmus Smit, Kate Templeton, Peter Tilston, Erik Volz, Hongyi Zhang, Keith Fairbrother, Justine Dawkins, Siobhan O’Shea, Jane Mullen, Alison Cox, Richard Tandy, Tracy Fawcett, Mark Hopkins, Clare Booth, Lynne Renwick, Matthias L. Schmid, Brendan Payne, Jonathan Hubb, Simon Dustan, Stuart Kirk, Amanda Bradley-Stewart, Sophie Jose, Alicia Thornton, Susie Huntington, Adam Glabay, Shaadi Shidfar, Janet Lynch, James Hand, Carl de Souza, Nicky Perry, Stuart Tilbury, Elaney Youssef, Brian Gazzard, Mark Nelson, Tracey Mabika, Sundhiya Mandalia, Jane Anderson, Sajid Munshi, Frank Post, Ade Adefisan, Chris Taylor, Zachary Gleisner, Fowzia Ibrahim, Lucy Campbell, Kirsty Baillie, Richard Gilson, Nataliya Brima, Jonathan Ainsworth, Achim Schwenk, Sheila Miller, Chris Wood, Margaret Johnson, Mike Youle, Fiona Lampe, Colette Smith, Rob Tsintas, Clinton Chaloner, Samantha Hutchinson, John Walsh, Nicky Mackie, Alan Winston, Jonathan Weber, Farhan Ramzan, Mark Carder, Clifford Leen, Alan Wilson, Sheila Morris, Mark Gompels, Sue Allan, Adrian Palfreeman, Adam Lewszuk, Stephen Kegg, Akin Faleye, Victoria Ogunbiyi, Sue Mitchell, Phillip Hay, Christian Kemble, Fabiola Martin, Sarah Russell-Sharpe, Janet Gravely, Sris Allan, Andrew Harte, Anjum Tariq, Hazel Spencer, Ron Jones, Jillian Pritchard, Shirley Cumming, Claire Atkinson, Dushyant Mital, Veronica Edgell, Juli Allen, Andy Ustianowski, Cynthia Murphy, Ilise Gunder, Roy Trevelion, Abdel Babiker

Publikováno v: Journal of Virus Eradication, Vol 5, Iss 4, Pp 204-211 (2019)

Objectives: The aim of this study was to investigate associations between baseline characteristics and CD4 cell count response on first-line antiretroviral therapy and risk of virological failure (VF) with or without drug resistance. Methods: We cond

Externí odkaz: https://doaj.org/article/b685ef625be34b15b9ad4ef446718de6

Active screening and surveillance in the United Kingdom for Middle East respiratory syndrome coronavirus in returning travellers and pilgrims from the Middle East: a prospective descriptive study for the period 2013–2015

Autor: Sowsan F. Atabani, Steven Wilson, Clare Overton-Lewis, Judith Workman, I. Michael Kidd, Eskild Petersen, Alimuddin Zumla, Erasmus Smit, Husam Osman

Publikováno v: International Journal of Infectious Diseases, Vol 47, Iss C, Pp 10-14 (2016)

Background: Over 25 000 pilgrims from the UK visit Saudi Arabia every year for the Umrah and Hajj pilgrimages. The recent outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in South Korea and the continuing reports of MERS-CoV cases

Externí odkaz: https://doaj.org/article/08658387aacf45348b30b31315e1d04b

A comparison of the performance of saliva and nasopharyngeal nucleic acid amplification testing for the detection of SARS-CoV-2 in New Zealand

Autor: Gary, McAuliffe, Tim, Blackmore, Juliet, Elvy, Shivani, Fox-Lewis, Brent, Gilpin, Jenny, Grant, Radhika, Nagappan, Erasmus, Smit, Chor Ee, Tan, Fernalynn, Tiongko, James, Ussher

Publikováno v: The New Zealand medical journal. 135(1559)

To compare detection of SARS-CoV-2 from paired nasopharyngeal swabs (NPS) and saliva using molecular methods in common use for testing swabs in New Zealand.Samples from individuals testing positive for SARS-CoV-2 in Auckland, Wellington and Dunedin w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aad595bc8c2e6a63db66e1e377fd4439
https://pubmed.ncbi.nlm.nih.gov/35999781

Sensitivity and potential utility of SARS-CoV-2 rapid antigen and nucleic acid amplification tests in the context of an elimination approach

Autor: Jenna, Beaumont, Mirsaed Miri, Nargesi, Susan, Smith, David, Harte, Erasmus, Smit, James, Ussher, Gary, McAuliffe

Publikováno v: The New Zealand medical journal. 134(1546)

To assess the sensitivity and potential utility of five RATs and the IDNow, Liat and Oxsed nucleic acid amplification tests (NAATs) in our population.39 retrospective and contrived SARS-CoV-2 positive samples were tested in parallel by standard RT-PC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05de3939349cf695335a8662189a8860
https://pubmed.ncbi.nlm.nih.gov/34855731

Lack of N2-gene amplification on the Cepheid Xpert Xpress SARS-CoV-2 assay and potential novel causative mutations: A case series from Auckland, New Zealand

Autor: Jing Wang, Joep de Ligt, Erasmus Smit, Gary McAuliffe, Susan Taylor, Jay Harrower, Andrew Fox-Lewis, Shivani Fox-Lewis, Richard Chen

Publikováno v: IDCases
IDCases, Vol 25, Iss, Pp e01233-(2021)

We describe three cases with viral strains that demonstrate impaired N2-gene detection on the Cepheid Xpert Xpress SARS-CoV-2 assay, with two previously undescribed single nucleotide polymorphisms (SNPs): C29197T and G29227T. We propose that these SN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf18396abffc73dc40d2f5549ec6a79
http://europepmc.org/articles/PMC8302484