Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Eranga Roshan"'
Autor:
Tsz-Yin Chan, Christina M. Egbert, Julia E. Maxson, Adam Siddiqui, Logan J. Larsen, Kristina Kohler, Eranga Roshan Balasooriya, Katie L. Pennington, Tsz-Ming Tsang, Madison Frey, Erik J. Soderblom, Huimin Geng, Markus Müschen, Tetyana V. Forostyan, Savannah Free, Gaelle Mercenne, Courtney J. Banks, Jonard Valdoz, Clifford J. Whatcott, Jason M. Foulks, David J. Bearss, Thomas O’Hare, David C. S. Huang, Kenneth A. Christensen, James Moody, Steven L. Warner, Jeffrey W. Tyner, Joshua L. Andersen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The mechanisms underlying the activity of non-receptor tyrosine kinase, TNK1, in cancers are unclear. Here the authors show that MARK mediates 14-3-3 and TNK1 interaction which restrains TNK1 activity, while the release of TNK1 from 14-3-3 leads to T
Externí odkaz:
https://doaj.org/article/3bf3573d63094261ac7abe05b09d7ee9
Akademický článek
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Autor:
Katherine K. McCormack, A.G. Pramoda Sahankumari, Katie L. Pennington, James Woods, Colten M. McEwan, Stephen R. Piccolo, Tyler Heaton, Joshua L. Andersen, Riley J. Eastmond, Manabu Kurokawa, Colin Muir, Eranga Roshan Balasooriya, Sandeep Kaur, Christina M. Egbert
Publikováno v:
Mol Cancer Res
PTOV1 is an oncogenic protein, initially identified in prostate cancer, that promotes proliferation, cell motility, and invasiveness. However, the mechanisms that regulate PTOV1 remain unclear. Here, we identify 14-3-3 as a PTOV1 interactor and show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9515fc0298c2e07bd6d499a23fa590f0
https://europepmc.org/articles/PMC8816884/
https://europepmc.org/articles/PMC8816884/
Autor:
Christina M. Egbert, Jeffrey W. Tyner, Gaelle Mercenne, Jonard Corpuz Valdoz, Logan Larsen, Tsz-Yin Chan, James D. Moody, Julia E. Maxson, Kristina Kohler, Tsz-Ming Tsang, Kenneth A. Christensen, Madison Frey, Courtney J. Banks, David J. Bearss, Adam Siddiqui, Tetyana V. Forostyan, Joshua L. Andersen, Huimin Geng, Jason M. Foulks, Savannah Free, Erik J. Soderblom, Thomas O'Hare, Steven L. Warner, David C.S. Huang, Katie L. Pennington, Eranga Roshan Balasooriya, Markus Müschen, Clifford J. Whatcott
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
TNK1 is a non-receptor tyrosine kinase with poorly understood biological function and regulation. Here, we identify TNK1 dependencies in primary human cancers. We also discover a MARK-mediated phosphorylation on TNK1 at S502 that promotes an interact
Autor:
Ashari R. Kannangara, Alex M Thornock, Daniel M. Poole, Colten M. McEwan, Erik J. Soderblom, Misael T Lazaro, Eranga Roshan Balasooriya, Joshua L. Andersen, Vajira K. Weerasekara, Joshua C Youngs, Daniel L. Simmons, Jonathan J Lee, Laura M Oh
Publikováno v:
EMBO Rep
ATG9A, the only multi‐pass transmembrane protein among core ATG proteins, is an essential regulator of autophagy, yet its regulatory mechanisms and network of interactions are poorly understood. Through quantitative BioID proteomics, we identify a
Akademický článek
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Autor:
Balasooriya, Eranga Roshan1,2, Jayasinghe, Chanika Dilumi1,3, Jayawardena, Uthpala Apekshani1,3, Ruwanthika, Ranasinghe Weerakkodige Dulashani2, Mendis de Silva, Rohini2, Udagama, Preethi Vidya1
Publikováno v:
Journal of Nanomaterials. 3/5/2017, p1-10. 10p.
Autor:
Julia E. Maxson, David C.S. Huang, Kristina Kohler, Jeremy Tsang, Eranga Roshan Balasooriya, Jeffrey W. Tyner, James D. Moody, Christina M. Egbert, Madison Frey, Logan Larsen, Kenneth A. Christensen, Joshua L. Andersen, Tsz Yin Chan
Publikováno v:
Cancer Research. 81:2306-2306
Tyrosine non-receptor kinase 1 (TNK1) is a poorly characterized member of the ACK family of non-receptor tyrosine kinases. We identified TNK1 as a mediator of cell survival in subsets of primary hematological malignancies. Previous studies have indic
Autor:
Clifford J. Whatcott, Steven L. Warner, Jeremy Tsang, Jason M. Foulks, David J. Bearss, Kenneth A. Christensen, Savannah Free, Tetyana V. Forostyan, Kim Wontak, Christina M. Egbert, James D. Moody, Jeffrey W. Tyner, Gaelle Mercenne, Tsz-Yin Chan, Adam Siddiqui, Joshua L. Andersen, Julia E. Maxson, Ethika Tyagi, Eranga Roshan, Logan Larsen
Publikováno v:
Cancer Research. 81:2307-2307
Sumitomo Dainippon Pharma Oncology (f/k/a Tolero Pharmaceuticals), Lehi, UTTNK1 is a poorly understood member of the ACK family of non-receptor tyrosine kinases with a unusual domain arrangement, but no known mechanism of regulation nor conclusive li
Autor:
Uthpala A. Jayawardena, Ranasinghe Weerakkodige Dulashani Ruwanthika, Preethi V. Udagama, Rohini M. de Silva, Chanika D. Jayasinghe, Eranga Roshan Balasooriya
Publikováno v:
Journal of Nanomaterials, Vol 2017 (2017)
With the advent of nanotechnology, many related industries rapidly developed over the recent past. Generally, top-down and bottom-up approaches are the two major processes used to synthesize nanoparticles; most of these require high temperatures, vac