Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Erandi Lira"'
Autor:
Ismael Compañón, Collin J. Ballard, Erandi Lira-Navarrete, Tanausú Santos, Serena Monaco, Juan C. Muñoz-García, Ignacio Delso, Jesus Angulo, Thomas A. Gerken, Katrine T. Schjoldager, Henrik Clausen, Tomás Tejero, Pedro Merino, Francisco Corzana, Ramon Hurtado-Guerrero, Mattia Ghirardello
Publikováno v:
JACS Au, Vol 4, Iss 9, Pp 3649-3656 (2024)
Externí odkaz:
https://doaj.org/article/ac3144beb28a4bf9854ce4dd4a027fb1
Autor:
Daniel Madriz Sørensen, Christian Büll, Thomas D. Madsen, Erandi Lira-Navarrete, Thomas Mandel Clausen, Alex E. Clark, Aaron F. Garretson, Richard Karlsson, Johan F. A. Pijnenborg, Xin Yin, Rebecca L. Miller, Sumit K. Chanda, Thomas J. Boltje, Katrine T. Schjoldager, Sergey Y. Vakhrushev, Adnan Halim, Jeffrey D. Esko, Aaron F. Carlin, Ramon Hurtado-Guerrero, Roberto Weigert, Henrik Clausen, Yoshiki Narimatsu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, the authors discover small molecules that inhibit glycosylation processes that occur in the Golgi apparatus of cells. The molecules reversibly inhibit formation of elaborate glycan structures without affecting secretion of glycoproteins.
Externí odkaz:
https://doaj.org/article/6c4688dc07fc45e1bcff09858f02a146
Autor:
Omar Al Rifai, Catherine Julien, Julie Lacombe, Denis Faubert, Erandi Lira-Navarrete, Yoshiki Narimatsu, Henrik Clausen, Mathieu Ferron
Publikováno v:
eLife, Vol 9 (2020)
Osteocalcin (OCN) is an osteoblast-derived hormone with pleiotropic physiological functions. Like many peptide hormones, OCN is subjected to post-translational modifications (PTMs) which control its activity. Here, we uncover O-glycosylation as a nov
Externí odkaz:
https://doaj.org/article/826e9b9ec7074a3ca22621417b1c0447
Autor:
Matilde de las Rivas, Earnest James Paul Daniel, Helena Coelho, Erandi Lira-Navarrete, Lluis Raich, Ismael Compañón, Ana Diniz, Laura Lagartera, Jesús Jiménez-Barbero, Henrik Clausen, Carme Rovira, Filipa Marcelo, Francisco Corzana, Thomas A. Gerken, Ramon Hurtado-Guerrero
Publikováno v:
ACS Central Science, Vol 4, Iss 9, Pp 1274-1290 (2018)
Externí odkaz:
https://doaj.org/article/63baa561e0fb4699b994035b11ea79d2
Autor:
Sergio Villanueva-Saz, Jacobo Giner, Antonio Fernández, Delia Lacasta, Aurora Ortín, Juan José Ramos, Luis Miguel Ferrer, Marta Ruiz de Arcaute, Ana Pilar Tobajas, María Dolores Pérez, Maite Verde, Diana Marteles, Ramón Hurtado-Guerrero, Julián Pardo, Llipsy Santiago, Andrés Manuel González-Ramírez, Javier Macías-León, Ana García-García, Víctor Taleb, Erandi Lira-Navarrete, José Ramón Paño-Pardo, Héctor Ruíz
Publikováno v:
Animals, Vol 11, Iss 7, p 1984 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the zoonotic causative agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic situation with millions of infected humans worldwide. Among domestic animals, there have be
Externí odkaz:
https://doaj.org/article/a7d06e4aa4a7402cae6c5c38fac148f8
Autor:
Matilde de las Rivas, Erandi Lira-Navarrete, Earnest James Paul Daniel, Ismael Compañón, Helena Coelho, Ana Diniz, Jesús Jiménez-Barbero, Jesús M. Peregrina, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Gonzalo Jiménez-Osés, Thomas A. Gerken, Ramon Hurtado-Guerrero
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
GalNAc transferases’ (GalNAc-Ts) catalytic domains are connected to a lectin domain through a flexible linker. Here the authors present a structural analysis of GalNAc-T4 that implicates the linker region as modulator of the orientations of the lec
Externí odkaz:
https://doaj.org/article/96c013e274ef4775a780ce73240387ed
Autor:
María Sebastián, Erandi Lira-Navarrete, Ana Serrano, Carlos Marcuello, Adrián Velázquez-Campoy, Anabel Lostao, Ramón Hurtado-Guerrero, Milagros Medina, Marta Martínez-Júlvez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Prokaryotic bifunctional FAD synthetases (FADSs) catalyze the biosynthesis of FMN and FAD, whereas in eukaryotes two enzymes are required for the same purpose. FMN and FAD are key cofactors to maintain the flavoproteome homeostasis in all ty
Externí odkaz:
https://doaj.org/article/d4edd25e669b41d59c704c9da5d7440d
Autor:
Erandi Lira-Navarrete, María Carmen Pallarés, Fabio Castello, Maria J. Ruedas-Rama, Angel Orte, Anabel Lostao, Ramón Hurtado-Guerrero
Publikováno v:
Molecules, Vol 26, Iss 8, p 2105 (2021)
Protein O-fucosyltransferase 1 (PoFUT1) is a GT-B fold enzyme that fucosylates proteins containing EGF-like repeats. GT-B glycosyltransferases have shown a remarkable grade of plasticity adopting closed and open conformations as a way of tuning their
Externí odkaz:
https://doaj.org/article/77e4189c54834dfab6e029a44325c973
Autor:
Jacobo Giner, Sergio Villanueva-Saz, Ana Pilar Tobajas, María Dolores Pérez, Ana González, Maite Verde, Andrés Yzuel, Ana García-García, Víctor Taleb, Erandi Lira-Navarrete, Ramón Hurtado-Guerrero, Julián Pardo, Llipsy Santiago, José Ramón Paño, Héctor Ruíz, Delia Lacasta, Antonio Fernández
Publikováno v:
Animals, Vol 11, Iss 3, p 667 (2021)
Animal infections with SARS-CoV-2 have been reported in different countries and several animal species have been proven to be susceptible to infection with SARS-CoV-2 both naturally and by experimental infection. Moreover, infections under natural co
Externí odkaz:
https://doaj.org/article/faf766fb06ad41e7b4fb3e4388d40a08
Autor:
Llipsy Santiago, Iratxe Uranga-Murillo, Maykel Arias, Andrés Manuel González-Ramírez, Javier Macías-León, Eduardo Moreo, Sergio Redrado, Ana García-García, Víctor Taleb, Erandi Lira-Navarrete, Ramón Hurtado-Guerrero, Nacho Aguilo, Maria del Mar Encabo-Berzosa, Sandra Hidalgo, Eva M. Galvez, Ariel Ramirez-Labrada, Diego de Miguel, Rafael Benito, Patricia Miranda, Antonio Fernández, José María Domingo, Laura Serrano, Cristina Yuste, Sergio Villanueva-Saz, José Ramón Paño-Pardo, Julián Pardo
Publikováno v:
Biology, Vol 10, Iss 3, p 208 (2021)
Several hundred millions of people have been diagnosed of coronavirus disease 2019 (COVID-19), causing millions of deaths and a high socioeconomic burden. SARS-CoV-2, the causative agent of COVID-19, induces both specific T- and B-cell responses, bei
Externí odkaz:
https://doaj.org/article/7bf26356635441678cd8335e9d4dcfe6