Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Erandi K De Silva"'
Autor:
Timothy James Russell, Erandi K De Silva, Valerie M Crowley, Kathryn Shaw-Saliba, Namita Dube, Gabrielle Josling, Charisse Flerida A Pasaje, Irene Kouskoumvekaki, Gianni Panagiotou, Jacquin C Niles, Marcelo Jacobs-Lorena, C Denise Okafor, Francisco-Javier Gamo, Manuel Llinás
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010887 (2022)
Plasmodium parasites are reliant on the Apicomplexan AP2 (ApiAP2) transcription factor family to regulate gene expression programs. AP2 DNA binding domains have no homologs in the human or mosquito host genomes, making them potential antimalarial dru
Externí odkaz:
https://doaj.org/article/32dbbe0804b44aea83886f60da9addc8
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001165 (2010)
The molecular mechanisms underlying transcriptional regulation in apicomplexan parasites remain poorly understood. Recently, the Apicomplexan AP2 (ApiAP2) family of DNA binding proteins was identified as a major class of transcriptional regulators th
Externí odkaz:
https://doaj.org/article/64fb0500a590460d9478ae50ec7bd8a2
Autor:
Timothy Russell, Erandi K. De Silva, Valerie Crowley, Kathryn Shaw-Saliba, Namita Dube, Gabrielle Josling, Charisse Flerida A. Pasaje, Irene Kouskoumvekaki, Gianni Panagiotou, Jacquin C. Niles, Marcelo Jacobs-Lorena, C. Denise Okafor, Francisco-Javier Gamo, Manuel Llinás
Plasmodium parasites are reliant on the Apicomplexan AP2 (ApiAP2) transcription factor family to regulate gene expression programs. AP2 DNA binding domains have no homologs in the human or mosquito host genomes, making them potential antimalarial dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253a5f707c33e906f4616a5d23b248c3
https://doi.org/10.1101/2022.04.05.487101
https://doi.org/10.1101/2022.04.05.487101
Publikováno v:
Journal of Molecular Biology. 395:558-567
Putative transcription factors have only recently been identified in the Plasmodium spp., with the major family of regulators comprising the Apicomplexan Apetala2 (AP2) proteins. To better understand the DNA-binding mechanisms of these transcriptiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafedb416cfeb1bad684431df2167b2c
https://doi.org/10.1016/j.jmb.2009.11.004
https://doi.org/10.1016/j.jmb.2009.11.004
Autor:
Yanfen Ma, William J. Sullivan, Erandi K. De Silva, Michael W. White, Louis M. Weiss, Joshua B. Radke, Olivier Lucas, Manuel Llinás
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(17)
Cellular differentiation leading to formation of the bradyzoite tissue cyst stage is the underlying cause of chronic toxoplasmosis. Consequently, mechanisms responsible for controlling development in the Toxoplasma intermediate life cycle have long b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb3c2ec1a17f55b2558393bce30d9a8
https://pubmed.ncbi.nlm.nih.gov/23572590
https://pubmed.ncbi.nlm.nih.gov/23572590
Autor:
Erandi K. De Silva, Manuel Llinás, Martha L. Bulyk, Kellen L. Olszewski, Andrew R. Gehrke, Jasdave S. Chahal, Ilsa León
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(24)
Malaria remains one of the most prevalent infectious diseases worldwide, affecting more than half a billion people annually. Despite many years of research, the mechanisms underlying transcriptional regulation in the malaria-causing Plasmodium spp.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61371b58e90da7962bdebc5384b9b92
https://pubmed.ncbi.nlm.nih.gov/18541913
https://pubmed.ncbi.nlm.nih.gov/18541913
Autor:
Philip C. Hanawalt, Silvia Tornaletti, Boris P. Belotserkovskii, Guliang Wang, Karen M. Vasquez, Erandi K. De Silva
Publikováno v:
The Journal of biological chemistry. 282(44)
Naturally occurring DNA sequences that are able to form unusual DNA structures have been shown to be mutagenic, and in some cases the mutagenesis induced by these sequences is enhanced by their transcription. It is possible that transcription-coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac883c1801c8acead40ce75b2923f98
https://pubmed.ncbi.nlm.nih.gov/17785457
https://pubmed.ncbi.nlm.nih.gov/17785457