Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eran Brown"'
Autor:
Eran Brown, Koya Ozawa, Federico Moccetti, Amanda Vinson, James Hodovan, The Anh Nguyen, Lindsay Bader, José A. López, Paul Kievit, Gray D. Shaw, Dominic W. Chung, Warren Osborn, Xiaoyun Fu, Junmei Chen, Jonathan R. Lindner
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 9 (2021)
Background Platelet–endothelial interactions are thought to contribute to early atherogenesis. These interactions are potentiated by oxidative stress. We used in vivo molecular imaging to test the hypothesis that platelet–endothelial interactions
Externí odkaz:
https://doaj.org/article/d3eb1c60c5774fd1bb4798a532628291
Autor:
Koya Ozawa, Paul S. Sheeran, Todd Belcik, Eran Brown, Matthew A. Muller, James Hodovan, Jonathan R. Lindner, Jeffry E. Powers
Publikováno v:
J Am Soc Echocardiogr
Cavitation of microbubble contrast agents with ultrasound produces shear-mediated vasodilation and an increase in tissue perfusion. We investigated the influence of the size of the cavitation volume by comparing flow augmentation produced by two-dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d2a5706e922230deb8242e615c52d5
https://doi.org/10.1016/j.echo.2021.02.018
https://doi.org/10.1016/j.echo.2021.02.018
Autor:
Federico Moccetti, Xiaoyun Fu, James Hodovan, José A. López, Lindsay Bader, Dominic W. Chung, Koya Ozawa, Gray D. Shaw, Eran Brown, Warren Osborn, Junmei Chen, Paul Kievit, Jonathan R. Lindner, Amanda Vinson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Platelet–endothelial interactions are thought to contribute to early atherogenesis. These interactions are potentiated by oxidative stress. We used in vivo molecular imaging to test the hypothesis that platelet–endothelial interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1ceb56080b5918baeafad6edc10c54
https://doi.org/10.1161/jaha.120.019413
https://doi.org/10.1161/jaha.120.019413
Autor:
Brian P. Davidson, Aris Xie, Eran Brown, William Packwood, Todd Belcik, Yllka Latifi, Azzdine Y. Ammi, Sabine Huke, Jonathan R. Lindner, Koya Ozawa, Federico Moccetti
Publikováno v:
J Am Soc Echocardiogr
BACKGROUND: Ultrasound-mediated cavitation of microbubble contrast agents produces high intravascular shear. We hypothesized that microbubble cavitation increases myocardial microvascular perfusion through shear-dependent purinergic pathways downstre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71181bca60ecfa7cab17d08b4d67e103
https://europepmc.org/articles/PMC7416478/
https://europepmc.org/articles/PMC7416478/
Autor:
Weihui Shentu, Koya Ozawa, The Anh Nguyen, Melinda D. Wu, William Packwood, Aris Xie, Matthew A. Muller, Eran Brown, Matthew W. Hagen, José A. López, Jonathan R. Lindner
Publikováno v:
J Am Soc Echocardiogr
Echocardiographic molecular imaging techniques are beginning to be applied to evaluate preclinical efficacy of new drugs. In a large clinical trial, anti-interleukin-1β (IL-1β) immunotherapy reduced atherosclerotic events, yet treatment effects wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f58bc04d1952348cca06606055c205
https://doi.org/10.1016/j.echo.2020.11.012
https://doi.org/10.1016/j.echo.2020.11.012
Autor:
Koya Ozawa, Junmei Chen, Owen J. T. McCarty, Javid Moslehi, Melinda Wu, Brian J. Druker, Eran Brown, William Packwood, Zaverio M. Ruggeri, Toshiaki Shirai, Federico Moccetti, Yue Qi, Jonathan R. Lindner, Aris Xie, Weihui Shentu, Yllka Latifi, José A. López
Publikováno v:
Blood. 133(14)
The third-generation tyrosine kinase inhibitor (TKI) ponatinib has been associated with high rates of acute ischemic events. The pathophysiology responsible for these events is unknown. We hypothesized that ponatinib produces an endothelial angiopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f374464e86ce88c76f84b3da2b4d0a
https://pubmed.ncbi.nlm.nih.gov/30948369
https://pubmed.ncbi.nlm.nih.gov/30948369
Autor:
Paul Kievit, Federico Moccetti, Jonathan R. Lindner, Lindsay A Bader, J. Todd Belcik, James Hodovan, Eran Brown, Koya Ozawa
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background: Platelet interactions with the vascular endothelium contribute to early atherogenesis, and occur in part from oxidative stress and secondary dysregulation of endothelial-associated von Willebrand factor (VWF). We used in vivo contrast enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::721c09fe960239a64eb2f735b0a0902a
https://doi.org/10.1161/atvb.38.suppl_1.044
https://doi.org/10.1161/atvb.38.suppl_1.044
Autor:
José A. López, Jonathan R. Lindner, Junmei Chen, Eran Brown, Aris Xie, William Packwood, Federico Moccetti, Zaverio M. Ruggeri, Weihui Shentu, Yue Qi
Publikováno v:
Journal of the American College of Cardiology. 72(9)
In the months after acute myocardial infarction (MI), risk for acute atherothrombotic events in nonculprit arteries increases several fold.This study investigated whether sustained proinflammatory and prothrombotic endothelial alterations occur in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd7b2260b02c19448e3c5e8694574fd
https://pubmed.ncbi.nlm.nih.gov/30139431
https://pubmed.ncbi.nlm.nih.gov/30139431
Autor:
Brian P. Davidson, Federico Moccetti, P. Barton Duell, Melinda D. Wu, Eran Brown, Sotirios Tsimikas, Sergio Fazio, Jonathan R. Lindner, George D. Giraud, Hagai Tavori, J. Todd Belcik, Tamara Atkinson
Publikováno v:
JACC. Cardiovascular imaging. 12(8 Pt 1)
This study evaluated whether lipoprotein apheresis produces immediate changes in resting perfusion in subjects with severe hypercholesterolemia, and whether there is a difference in the response between peripheral and coronary microcirculations.Lipop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac79dd3488f450fd4f5d3784278964e
https://pubmed.ncbi.nlm.nih.gov/30553683
https://pubmed.ncbi.nlm.nih.gov/30553683
Publikováno v:
Procedia Engineering. 107:387-394
The rise of diabetes in Kenya presents many challenges to a healthcare system struggling to deal with communicable diseases such as HIV and malaria. The lack of a proper system in place to quickly and effectively diagnose diabetes, especially in remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce52421aa729173718585e4a42d3ff8