Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Eran Agmon"'
Autor:
John W. Hickey, Maximillian Haist, Nina Horowitz, Chiara Caraccio, Yuqi Tan, Andrew J. Rech, Marc-Andrea Baertsch, Xavier Rovira-Clavé, Bokai Zhu, Gustavo Vazquez, Graham Barlow, Eran Agmon, Yury Goltsev, John B. Sunwoo, Markus Covert, Garry P. Nolan
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113494- (2023)
Summary: Antigen-specific T cells traffic to, are influenced by, and create unique cellular microenvironments. Here we characterize these microenvironments over time with multiplexed imaging in a melanoma model of adoptive T cell therapy and human pa
Externí odkaz:
https://doaj.org/article/23bca3d4eb344078ba8c41980512f8de
Autor:
Christopher J Skalnik, Sean Y Cheah, Mica Y Yang, Mattheus B Wolff, Ryan K Spangler, Lee Talman, Jerry H Morrison, Shayn M Peirce, Eran Agmon, Markus W Covert
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011232 (2023)
Antibiotic resistance poses mounting risks to human health, as current antibiotics are losing efficacy against increasingly resistant pathogenic bacteria. Of particular concern is the emergence of multidrug-resistant strains, which has been rapid amo
Externí odkaz:
https://doaj.org/article/c586e70966d047e2adda5d4777ce5255
Autor:
Graham T. Johnson, Eran Agmon, Matthew Akamatsu, Emma Lundberg, Blair Lyons, Wei Ouyang, Omar A. Quintero-Carmona, Megan Riel-Mehan, Susanne Rafelski, Rick Horwitz
Publikováno v:
Biophysical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aa18095f51adfec6dffac4dabbdbd20
https://doi.org/10.1016/j.bpj.2023.04.006
https://doi.org/10.1016/j.bpj.2023.04.006
Autor:
Eran Agmon, Ryan K. Spangler
Publikováno v:
Entropy, Vol 22, Iss 10, p 1101 (2020)
The degree to which we can understand the multi-scale organization of cellular life is tied to how well our models can represent this organization and the processes that drive its evolution. This paper uses Vivarium—an engine for composing heteroge
Externí odkaz:
https://doaj.org/article/b8c74ddbbf184e169009491e472ede7b
Autor:
Markus W. Covert, Christopher J Skalnik, Shayn M. Peirce, Morrison Jh, William Poole, Ryan K. Spangler, Eran Agmon
Publikováno v:
Bioinformatics
Motivation This article introduces Vivarium—software born of the idea that it should be as easy as possible for computational biologists to define any imaginable mechanistic model, combine it with existing models and execute them together as an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b780e92d557516919ee6fb85ca74ea4d
https://europepmc.org/articles/PMC8963310/
https://europepmc.org/articles/PMC8963310/
Publikováno v:
Cell Syst
Summary Quantitative systems biology, in which predictive mathematical models are constructed to guide the design of experiments and predict experimental outcomes, is at an exciting transition point, where the foundational scientific principles are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543149b13db699945d1c8c1dc2ac21c4
https://europepmc.org/articles/PMC8217727/
https://europepmc.org/articles/PMC8217727/
Publikováno v:
Current Opinion in Biomedical Engineering. 11:102-108
Summary Bacterial and viral pathogens affect the homeostasis of their hosts in complex and oftentimes unintuitive ways. Mechanistic insights into these host–pathogen interactions may one day allow us to discover more effective antimicrobials and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753c677a23d97e29f4605eea307102e7
https://doi.org/10.1016/j.cobme.2019.10.001
https://doi.org/10.1016/j.cobme.2019.10.001
Autor:
Lee Talman, Eran Agmon, Christopher J Skalnik, Shayn M. Peirce, Morrison Jh, Markus W. Covert, Ryan K. Spangler
Bacterial behavior is the outcome of both molecular mechanisms within each cell and interactions between cells in the context of their environment. Whereas whole-cell models simulate a single cell’s behavior using molecular mechanisms, agent-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40340f811e8d6fe5b8af8054ee8be730
https://doi.org/10.1101/2021.04.27.441666
https://doi.org/10.1101/2021.04.27.441666
Autor:
Eran Agmon, Markus W. Covert
Publikováno v:
Computational Modeling: From Chemistry to Materials to Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf3f10ba1e6a63d6a047f432169a8c3
https://doi.org/10.1142/9789811228216_0038
https://doi.org/10.1142/9789811228216_0038
Autor:
Ryan K. Spangler, Eran Agmon
Publikováno v:
Entropy, Vol 22, Iss 1101, p 1101 (2020)
Entropy
Volume 22
Issue 10
Entropy
Volume 22
Issue 10
The degree to which we can understand the multi-scale organization of cellular life is tiedto how well our models can represent this organization and the processes that drive its evolution.This paper uses Vivarium&mdash
an engine for composing h
an engine for composing h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c893a8de7db2e680c59f3a8615e7bd
https://www.mdpi.com/1099-4300/22/10/1101
https://www.mdpi.com/1099-4300/22/10/1101