Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Eram MS"'
Autor:
Trush VV; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Feller C; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, HPM H 25, Otto Stern Weg 2, 8093 Zurich, Switzerland., Li ASM; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada., Allali-Hassani A; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Chau I; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Jiang B; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada., Luu R; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada., Zhang F; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, HPM H 25, Otto Stern Weg 2, 8093 Zurich, Switzerland., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada; Nature Research Center, Vilnius, Akademijos 2, Lithuania., Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, HPM H 25, Otto Stern Weg 2, 8093 Zurich, Switzerland; Faculty of Science, University of Zurich, Zurich, Switzerland., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 2M9, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: m.vedadi@utoronto.ca.
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2022 Jul; Vol. 1865 (5), pp. 194845. Date of Electronic Publication: 2022 Jul 28.
Autor:
Shen Y; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Halabelian L; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Chau I; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Dela Seña C; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Park KS; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Meng F; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Chen H; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Zeng H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Dong A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Wu H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Trush VV; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., McLeod D; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada., Zepeda-Velázquez CA; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada., Campbell RM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States., Mader MM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States., Watson BM; Eli Lilly and Company, Lilly Research Laboratories, Indianapolis, Indiana 46225, United States., Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Al-Awar R; Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Kaniskan HÜ; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Jin J; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Apr 08; Vol. 64 (7), pp. 3697-3706. Date of Electronic Publication: 2021 Feb 16.
Autor:
Li ASM; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada., Li F; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Bolotokova A; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Dela Seña CC; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: m.vedadi@utoronto.ca.
Publikováno v:
Methods (San Diego, Calif.) [Methods] 2020 Mar 15; Vol. 175, pp. 30-43. Date of Electronic Publication: 2019 Dec 03.
Autor:
Allali-Hassani A; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Ivanochko D; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada., Organ SL; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Bok J; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ho JSY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Gay FPH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Li F; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Blazer L; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Halabelian L; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Dilworth D; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Luciani GM; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Lima-Fernandes E; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Wu Q; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Loppnau P; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Palmer N; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Talib SZA; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada., Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada., Kaldis P; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; National University of Singapore (NUS), Department of Biochemistry, 117597, Singapore, Singapore., O'Hagan RC; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA., Guccione E; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Pharmacological Sciences and Mount Sinai Center for Therapeutics Discovery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Nature Research Center, Vilnius, Akademijos, 2, Lithuania., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9, Canada., Sanders JM; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA., Kattar SD; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA., Bennett DJ; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA., Nicholson B; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ, 07033, USA. benjamin.nicholson@merck.com., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada. m.vedadi@utoronto.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada. m.vedadi@utoronto.ca.
Publikováno v:
Nature communications [Nat Commun] 2019 Dec 17; Vol. 10 (1), pp. 5759. Date of Electronic Publication: 2019 Dec 17.
Autor:
de Araujo ED; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Erdogan F; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Neubauer HA; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.; Ludwig Boltzmann Institute for Cancer Research, 1090, Vienna, Austria., Meneksedag-Erol D; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Physics, University of Toronto, 60 St. George Street, Toronto, ON, M5S 1A7, Canada., Manaswiyoungkul P; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Eram MS; Dalriada Drug Discovery, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada., Seo HS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA., Qadree AK; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Israelian J; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada., Orlova A; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.; Ludwig Boltzmann Institute for Cancer Research, 1090, Vienna, Austria., Suske T; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria., Pham HTT; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.; Ludwig Boltzmann Institute for Cancer Research, 1090, Vienna, Austria., Boersma A; Institute of Laboratory Animal Science, University of Veterinary Medicine Vienna, 1210, Vienna, Austria., Tangermann S; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210, Vienna, Austria., Kenner L; Ludwig Boltzmann Institute for Cancer Research, 1090, Vienna, Austria.; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.; Clinical Institute of Pathology, Department for Experimental and Laboratory Animal Pathology, Medical University of Vienna, 1090, Vienna, Austria., Rülicke T; Institute of Laboratory Animal Science, University of Veterinary Medicine Vienna, 1210, Vienna, Austria., Dong A; Structural Genomics Consortium, University of Toronto, 101 College St., Toronto, ON, M5G 1L7, Canada., Ravichandran M; Structural Genomics Consortium, University of Toronto, 101 College St., Toronto, ON, M5G 1L7, Canada., Brown PJ; Structural Genomics Consortium, University of Toronto, 101 College St., Toronto, ON, M5G 1L7, Canada., Audette GF; Department of Chemistry, York University, 327C Life Sciences Building, 4700 Keele Street, Toronto, ON, M3J 1P3, Canada., Rauscher S; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada.; Department of Physics, University of Toronto, 60 St. George Street, Toronto, ON, M5S 1A7, Canada., Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA. dhepag@crystal.harvard.edu.; Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA. dhepag@crystal.harvard.edu., Moriggl R; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210, Vienna, Austria. richard.moriggl@vetmeduni.ac.at.; Ludwig Boltzmann Institute for Cancer Research, 1090, Vienna, Austria. richard.moriggl@vetmeduni.ac.at.; Medical University of Vienna, 1090, Vienna, Austria. richard.moriggl@vetmeduni.ac.at., Gunning PT; Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada. patrick.gunning@utoronto.ca.; Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON, M5S 3H6, Canada. patrick.gunning@utoronto.ca.
Publikováno v:
Nature communications [Nat Commun] 2019 Jun 07; Vol. 10 (1), pp. 2517. Date of Electronic Publication: 2019 Jun 07.
Autor:
Bonday ZQ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Cortez GS; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Grogan MJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Antonysamy S; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Weichert K; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Bocchinfuso WP; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Li F; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Kennedy S; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Li B; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Mader MM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto and Princess Margaret Cancer Centre, 101 College Street, MaRS South Tower, Suite 707, Toronto, ON M5G 1L7, Canada., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada., Guccione E; Institute of Molecular and Cell Biology, Singapore 138673., Campbell RM; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Apr 23; Vol. 9 (7), pp. 612-617. Date of Electronic Publication: 2018 Apr 23 (Print Publication: 2018).
Autor:
Nakayama K; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Szewczyk MM; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Dela Sena C; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Wu H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Dong A; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Zeng H; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Li F; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., de Freitas RF; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Baba Y; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Kunitomo M; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Cary DR; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Tawada M; Medicinal Chemistry Research Laboratory, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Ohashi A; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Imaeda Y; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Saikatendu KS; Structiural Biology, Takeda California Inc., 10410 Science Center Drive, San Diego, CA 92121, USA., Grimshaw CE; Enzymology and Biophysical Chemistry, Takeda California Inc., 10410 Science Center Drive, San Diego, CA 92121, USA., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada., Kiba A; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Tomita D; Oncology Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Kanagawa 251-8555, Japan., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Publikováno v:
Oncotarget [Oncotarget] 2018 Apr 06; Vol. 9 (26), pp. 18480-18493. Date of Electronic Publication: 2018 Apr 06 (Print Publication: 2018).
Autor:
Kaniskan HÜ; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States., Eram MS; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Zhao K; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Szewczyk MM; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Yang X; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States., Schmidt K; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States., Luo X; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Xiao S; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Dai M; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., He F; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Zang I; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Lin Y; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Li F; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Dobrovetsky E; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Smil D; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Min SJ; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States., Lin-Jones J; DiscoveRx Corporation , Fremont, California 94538, United States., Schapira M; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto , Toronto, ON M5S 1A8, Canada., Atadja P; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Li E; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Arrowsmith CH; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto and Princess Margaret Cancer Centre , 101 College Street, MaRS South Tower, Suite 707, Toronto, ON M5G 1L7, Canada., Brown PJ; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada., Liu F; Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and Department of Medicinal Chemistry, College of Pharmaceutical Sciences, Soochow University , Suzhou, Jiangsu 215123, China., Yu Z; Novartis Institutes for Biomedical Research (China), Zhangjiang Hi-Tech Park , Pudong New Area, Shanghai 201203, China., Vedadi M; Structural Genomics Consortium, University of Toronto , Toronto, ON M5G 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto , Toronto, ON M5S 1A8, Canada., Jin J; Center for Chemical Biology and Drug Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2018 Feb 08; Vol. 61 (3), pp. 1204-1217. Date of Electronic Publication: 2018 Jan 05.
Autor:
Bergamin E; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Sarvan S; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Malette J; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5J 1L7, Canada., Yeung S; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Mongeon V; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Joshi M; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Brunzelle JS; Northwestern Synchrotron Research Center, Life Sciences Collaborative Access Team, Northwestern University, Argonne, IL 60439, USA., Michaels SD; Department of Biology, Indiana University, 915 East Third Street, Bloomington, IN 47405, USA., Blais A; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada., Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, Ontario M5J 1L7, Canada.; Department of Pharmacology and Toxicology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Couture JF; Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5, Canada.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2017 Jun 20; Vol. 45 (11), pp. 6375-6387.
Autor:
Vedadi M; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8., Blazer L; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7., Eram MS; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7.; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 2M9., Hajian T; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7.
Publikováno v:
Protein science : a publication of the Protein Society [Protein Sci] 2017 Apr; Vol. 26 (4), pp. 662-676. Date of Electronic Publication: 2017 Mar 06.