Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eraj Shafiq Khokhar"'
Autor:
Raed Ibraheim, Phillip W. L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás C. Rodríguez, Suk Namkung, Samantha Nelson, Eraj Shafiq Khokhar, Esther Mintzer, Stacy Maitland, Zexiang Chen, Yueying Cao, Emmanouela Tsagkaraki, Scot A. Wolfe, Dan Wang, Athma A. Pai, Wen Xue, Guangping Gao, Erik J. Sontheimer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Long-term expression of Cas9 following precision genome editing in vivo may lead to undesirable consequences. Here we show that a single-vector, self-inactivating AAV system containing Cas9 nuclease, guide, and DNA donor can use homology-directed rep
Externí odkaz:
https://doaj.org/article/81e517a4261d442a884395258d491bfe
Autor:
Tim Stearns, Sneha Borikar, Elizabeth Eudy, Kira Young, Jennifer J. Trowbridge, Eraj Shafiq Khokhar
SummaryAged hematopoietic stem cells (HSCs) undergo biased lineage priming and differentiation toward production of myeloid cells. A comprehensive understanding of gene regulatory mechanisms causing HSC aging is needed to devise new strategies to sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2e303d956e3cad145426c3019271e7
https://doi.org/10.1101/679738
https://doi.org/10.1101/679738
Autor:
Kira Young, Jennifer J. Trowbridge, Elizabeth Eudy, Sneha Borikar, Tim Stearns, Eraj Shafiq Khokhar
Publikováno v:
Exp Hematol
Aged hematopoietic stem cells (HSCs) undergo biased lineage priming and differentiation toward production of myeloid cells. A comprehensive understanding of gene regulatory mechanisms causing HSC aging is needed to devise new strategies to sustainabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f96ae07d611547744acb5c9e8efd4b
https://doi.org/10.1016/j.exphem.2020.01.014
https://doi.org/10.1016/j.exphem.2020.01.014
Autor:
Dustin L. Updike, Michael Senter-Zapata, Paige C. Tanner, Anne C. Campbell, Ashley L. Kelly, Markus Terrey, Eraj Shafiq Khokhar, Karolina M. Andralojc, Ian M. Gans
Publikováno v:
PLoS Genetics
Plos Genetics, 13, 1-20
Plos Genetics, 13, 2, pp. 1-20
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Plos Genetics, 13, 1-20
Plos Genetics, 13, 2, pp. 1-20
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722e79a1d446bb52bb9c352af7181163
https://doi.org/10.1371/journal.pgen.1006611
https://doi.org/10.1371/journal.pgen.1006611