Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Era L. Pogosova‐Agadjanyan"'
Autor:
Jasmine Naru, Megan Othus, ChenWei Lin, Melinda A. Biernacki, Marie Bleakley, Thomas R. Chauncey, Harry P. Erba, Min Fang, Matthew P. Fitzgibbon, Phillip R. Gafken, Richard G. Ivey, Jacob J. Kennedy, Travis D. Lorentzen, Soheil Meshinchi, Anna Moseley, Era L. Pogosova‐Agadjanyan, Vivian M. Liu, Jerald P. Radich, Uliana J. Voytovich, Pei Wang, Jeffrey R. Whiteaker, Cheryl L. Willman, Feinan Wu, Amanda G. Paulovich, Derek L. Stirewalt
Publikováno v:
eJHaem, Vol 5, Iss 6, Pp 1243-1251 (2024)
Abstract Introduction Acute myeloid leukemia (AML) remains one of the deadliest hematopoietic malignancies. A better understanding of the molecular biology governing AML may lead to improved risk stratification and facilitate the development of novel
Externí odkaz:
https://doaj.org/article/18d3b04e042e48a2a897b435a871a0b6
Autor:
Era L. Pogosova-Agadjanyan, Xing Hua, Megan Othus, Frederick R. Appelbaum, Thomas R. Chauncey, Harry P. Erba, Matthew P. Fitzgibbon, Isaac C. Jenkins, Min Fang, Stanley C. Lee, Anna Moseley, Jasmine Naru, Jerald P. Radich, Jenny L. Smith, Brooke E. Willborg, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background Studies have not systematically compared the ability to verify performance of prognostic transcripts in paired bulk mononuclear cells versus viable CD34-expressing leukemic blasts from patients with acute myeloid leukemia. We hypo
Externí odkaz:
https://doaj.org/article/068af1ff03784be8bc61228665d49697
Autor:
Christina M. Termini, Anna Moseley, Megan Othus, Frederick R. Appelbaum, Thomas R. Chauncey, Harry P. Erba, Min Fang, Stanley C. Lee, Jasmine Naru, Era L. Pogosova-Agadjanyan, Jerald P. Radich, Cheryl L. Willman, Feinan Wu, Soheil Meshinchi, Derek L. Stirewalt
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/4c2f1cc13a4d4e82997fde8282f05c18
Autor:
Eline J.M. Bertrums, Jenny L. Smith, Lauren Harmon, Rhonda E. Ries, Yi-Cheng J. Wang, Todd A. Alonzo, Andrew J. Menssen, Karen M. Chisholm, Amanda R. Leonti, Katherine Tarlock, Fabiana Ostronoff, Era L. Pogosova-Agadjanyan, Gertjan J.L. Kaspers, Henrik Hasle, Michael Dworzak, Christiane Walter, Nora Muhlegger, Cristina Morerio, Laura Pardo, Betsy Hirsch, Susana Raimondi, Todd M. Cooper, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Jason E. Farrar, Derek Stirewalt, Xiaotu Ma, Tim I. Shaw, Scott N. Furlan, Lisa Eidenschink Brodersen, Michael R. Loken, Marry M. van den Heuvel-Eibrink, C. Michel Zwaan, Timothy J. Triche, Bianca F. Goemans, Soheil Meshinchi
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
NUP98 fusions comprise a family of rare recurrent alterations in AML, associated with adverse outcomes. In order to define the underlying biology and clinical implications of this family of fusions, we performed comprehensive transcriptome, epigenome
Externí odkaz:
https://doaj.org/article/831b66d955b24822ab485927eae2ccd2
Autor:
Era L. Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R. Appelbaum, Thomas R. Chauncey, I-Ming L. Chen, Harry P. Erba, John E. Godwin, Isaac C. Jenkins, Min Fang, Mike Huynh, Kenneth J. Kopecky, Alan F. List, Jasmine Naru, Jerald P. Radich, Emily Stevens, Brooke E. Willborg, Cheryl L. Willman, Brent L. Wood, Qing Zhang, Soheil Meshinchi, Derek L. Stirewalt
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The recently updated European LeukemiaNet risk stratification guidelines combine cytogenetic abnormalities and genetic mutations to provide the means to triage patients with acute myeloid leukemia for optimal therapies. Despite th
Externí odkaz:
https://doaj.org/article/066cab4547fe4d0eae3f37a2fba497cb
Autor:
Jason E. Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda Ries, Tiffany Hylkema, Era L. Pogosova-Agadjanyan, Sneha Challa, Amanda Leonti, Timothy I. Shaw, Timothy J. Triche, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Xiaotu Ma, Derek L. Stirewalt, Todd A. Alonzo, Soheil Meshinchi
Publikováno v:
Journal of Clinical Oncology. 41:2949-2962
PURPOSE Optimized strategies for risk classification are essential to tailor therapy for patients with biologically distinctive disease. Risk classification in pediatric acute myeloid leukemia (pAML) relies on detection of translocations and gene mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ef473648313347225baef9d1b228a4
https://doi.org/10.1200/jco.22.01114
https://doi.org/10.1200/jco.22.01114
Autor:
Miranda C. Lahman, Thomas M. Schmitt, Kelly G. Paulson, Nathalie Vigneron, Denise Buenrostro, Felecia D. Wagener, Valentin Voillet, Lauren Martin, Raphael Gottardo, Jason Bielas, Julie M. McElrath, Derek L. Stirewalt, Era L. Pogosova-Agadjanyan, Cecilia C. Yeung, Robert H. Pierce, Daniel N. Egan, Merav Bar, Paul C. Hendrie, Sinéad Kinsella, Aesha Vakil, Jonah Butler, Mary Chaffee, Jonathan Linton, Megan S. McAfee, Daniel S. Hunter, Marie Bleakley, Anthony Rongvaux, Benoit J. Van den Eynde, Aude G. Chapuis, Philip D. Greenberg
Publikováno v:
Sci Transl Med
Science translational medicine, Vol. 14, no.631, p. eabg8070 (2022)
Science translational medicine, Vol. 14, no.631, p. eabg8070 (2022)
Designing effective antileukemic immunotherapy will require understanding mechanisms underlying tumor control or resistance. Here, we report a mechanism of escape from immunologic targeting in an acute myeloid leukemia (AML) patient, who relapsed 1 y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ab8910054866ad4b7f3c2247308f44
https://doi.org/10.1126/scitranslmed.abg8070
https://doi.org/10.1126/scitranslmed.abg8070
Autor:
Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi
Publikováno v:
Blood. 140:9173-9174
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::537d9182faa23ac3c8f3e3046a36543a
https://doi.org/10.1182/blood-2022-168296
https://doi.org/10.1182/blood-2022-168296
Autor:
Qing Zhang, Kenneth J. Kopecky, Thomas R. Chauncey, Era L. Pogosova-Agadjanyan, John E. Godwin, Cheryl L. Willman, Jerald P. Radich, Emily A. Stevens, Frederick R. Appelbaum, Anna Moseley, Min Fang, I-Ming L. Chen, Megan Othus, Isaac C. Jenkins, Harry P. Erba, Soheil Meshinchi, Mike Huynh, Brent L. Wood, Alan F. List, Derek L. Stirewalt, Brooke E. Willborg, Jasmine Naru
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-13 (2020)
Biomarker Research
Biomarker Research
Background The recently updated European LeukemiaNet risk stratification guidelines combine cytogenetic abnormalities and genetic mutations to provide the means to triage patients with acute myeloid leukemia for optimal therapies. Despite the identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ede634f4f96fd17750127cbe5842175
http://link.springer.com/article/10.1186/s40364-020-00208-1
http://link.springer.com/article/10.1186/s40364-020-00208-1
Autor:
Era L Pogosova-Agadjanyan, Kenneth J Kopecky, Fabiana Ostronoff, Frederick R Appelbaum, John Godwin, Hana Lee, Alan F List, Jennifer J May, Vivian G Oehler, Steve Petersdorf, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Soheil Meshinchi, Derek L Stirewalt
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70812 (2013)
Interferon regulatory factor 8 (IRF8) is a transcription factor that plays a critical role in normal hematopoiesis, such that disruption of IRF8 activity promotes leukemogenesis. We and others have identified aberrant expression of IRF8 transcripts,
Externí odkaz:
https://doaj.org/article/802ab39693844aa190b3966c2085e848