Zobrazeno 1 - 10
of 1 023
pro vyhledávání: '"Epithelial-mesenchymal transformation"'
Autor:
Weihong Chen, Mingyuan Chen, Lingju Hong, Abudukeremu Xiahenazi, Maotuan Huang, Nanhong Tang, Xinyue Yang, Feifei She, Yanling Chen
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Background The predominant immune cells in solid tumors are M2-like tumor-associated macrophages (M2-like TAMs), which significantly impact the promotion of epithelial-mesenchymal transition (EMT) in tumors, enhancing stemness and facilitati
Externí odkaz:
https://doaj.org/article/87f4d6cbd0214a18ac9955a8afb48606
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 3433-3442 (2024)
Jun Cao,1,2 Hao Zhang,2 Xin Xie,3 Wei Wang4 1Department of Oncology, The Third Affiliated Hospital of Xi’an Medical University, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Department of Surgical Oncology, The First Affiliated Hospital
Externí odkaz:
https://doaj.org/article/593f59acd0e244f3b40cf7d586d410a6
Publikováno v:
环境与职业医学, Vol 41, Iss 6, Pp 687-693 (2024)
BackgroundCoal workers' pneumoconiosis (CWP) is a serious occupational lung disease and one of the prescript occupational diseases in China. Epithelial-mesenchymal transition (EMT) is involved in the diffuse fibrosis of lung tissue of pneumoconiosis
Externí odkaz:
https://doaj.org/article/e6263e5290c147ac85b5f474e275f81b
Autor:
Cunxiang Bo, Fang Liu, Zewen Zhang, Zhongjun Du, Haidi Xiu, Zhenling Zhang, Ming Li, Caiqing Zhang, Qiang Jia
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Simvastatin (Sim), a hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has been widely used in prevention and treatment of cardiovascular diseases. Studies have suggested that Sim exerts anti-fibrotic effects by int
Externí odkaz:
https://doaj.org/article/a52dd4f5df3c4d129270bda320f53129
Autor:
Xuedan Han, Hai Qin, Yu Lu, Haitao Chen, Zhengdong Yuan, Yiwen Zhang, Xuena Yang, Lufeng Zheng, Simin Yan
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34015- (2024)
While strides in cancer treatment continue to advance, the enduring challenges posed by cancer metastasis and recurrence persist as formidable contributors to the elevated mortality rates observed in cancer patients. Among the multifaceted factors im
Externí odkaz:
https://doaj.org/article/7cc3b67e066a497ab809e9c991994f55
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background and purpose Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid peroxidation. Its role in cancer metastasis remains unclear. In this study, we aimed to investigate the potential involvement of ferro
Externí odkaz:
https://doaj.org/article/b10013bd47db4f81915be3522b0ecbd0
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background The epithelial–mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells participated in the development of retinal fibrosis. SB431542 is a small molecule inhibitor with inhibitory effects on the ALK4, ALK5 and ALK7
Externí odkaz:
https://doaj.org/article/52bc7da572254ecba1c02d71f78d04df
Autor:
Chen Ting, Zhou Yu
Publikováno v:
Xin yixue, Vol 54, Iss 12, Pp 845-848 (2023)
Phosphatidylinositol-3， 4， 5-triphosphate-dependent Rac exchange factor 1 （PREX1） is a coding gene that is abnormally expressed in a variety of tumors. As a guanine nucleotide exchange factor （RacGEF） of small GTP binding protein Rac1，
Externí odkaz:
https://doaj.org/article/c362b2bb077143b2acb48abb7141cd1c
Publikováno v:
Environment International, Vol 186, Iss , Pp 108656- (2024)
Cadmium (Cd) is an accumulative toxic metal which poses a serious threat to human health, even in trace amounts. One of the most important steps in the pathophysiology of lung cancer (LC) is the epithelial-mesenchymal transition (EMT). In this invest
Externí odkaz:
https://doaj.org/article/38ecb378c91a4aefaacc3f2ae4c7ba84
Autor:
Yanli Zhu, Xue Zhang, Yi Chen, Qianli Liu, Jin Yang, Xiaoxiao Fan, Hanjun Song, Zhuoxin Cheng, Shuang Liu
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27155- (2024)
At present, surgical resection is the most effective method for the treatment of gastric cancer. However, death caused by inoperable metastasis is still very common, despite research in this area. The mechanisms underlying the occurrence, development
Externí odkaz:
https://doaj.org/article/7aed067c365c4a7181a38d28191e2882