Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Epithelial fluid transport"'
Autor:
Saumel Ahmadi, Chong Jiang, Daniela Rotin, Jia Xin Jiang, Sunny Xia, Zoltan Bozoky, Michelle DiPaola, Onofrio Laselva, Nicola L. Jones, Christopher N. Mayhew, Christine E. Bear, Amy Pitstick
Induced Pluripotent Stem Cells (iPSCs) can be differentiated into epithelial organoids that recapitulate the relevant context for CFTR and enable testing of therapies targeting Cystic Fibrosis (CF)-causing mutant proteins. However, to date, CF-iPSC-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb30074a99bc629df9ef0b2035f27685
https://doi.org/10.1101/2021.07.07.451180
https://doi.org/10.1101/2021.07.07.451180
Autor:
Neerincx, Anne H., Whiteson, Katrine, Phan, Joann L., Brinkman, Paul, Abdel-Aziz, Mahmoud I., Weersink, Els J.M., Altenburg, Josje, Majoor, Christof J., Maitland-van der Zee, Anke H., Bos, Lieuwe D.J., Haarman, E., Rutjes, N. W., Terheggen-Lagro, S. W.J., Seljogi, D., Kemper, E. M., Lutter, R., Vijverberg, S. J., Vonk, S. E.M., Adriaens, N., Lub, R., van Brederode, M., van der Schaaf, L., Verkleij, M., van Gilst, N. A., Hofsteenge, G. H., Brackel, C. L.H., Lakeman, P., Bon, I. C.M., Tanner, S. P.M., Sterk, P. J., Longo, C., Sinha, A., Fenn, D., Lammers, A., Richards, L. B., van Bragt, J. M., Kos, R., Dagelet, J. W.F., Lone-Latif, S. J.A., Schultz, M. J., Smit, M. R., Hagens, L. A.
Publikováno v:
Neerincx, A H, Whiteson, K, Phan, J L, Brinkman, P, Abdel-Aziz, M I, Weersink, E J M, Altenburg, J, Majoor, C J, Maitland-van der Zee, A H, Bos, L D J, Haarman, E, Rutjes, N W, Terheggen-Lagro, S W J, Seljogi, D, Kemper, E M, Lutter, R, Vijverberg, S J, Vonk, S E M, Adriaens, N, Lub, R, van Brederode, M, van der Schaaf, L, Verkleij, M, van Gilst, N A, Hofsteenge, G H, Brackel, C L H, Lakeman, P, Bon, I C M, Tanner, S P M, Sterk, P J, Longo, C, Sinha, A, Fenn, D, Lammers, A, Richards, L B, van Bragt, J M, Kos, R, Dagelet, J W F, Lone-Latif, S J A, Schultz, M J, Smit, M R, Hagens, L A, Amsterdam mucociliary clearance disease research group & Amsterdam UMC Breath Research Group 2021, ' Lumacaftor/ivacaftor changes the lung microbiome and metabolome in cystic fibrosis patients ', ERJ Open Research, vol. 7, no. 2, 00731-2020 . https://doi.org/10.1183/23120541.00731-2020
ERJ Open Research, 7(2):00731-2020. BMJ Publishing Group
ERJ Open Research
article-version (VoR) Version of Record
ERJ open research, 7(2):00731-2020. European Respiratory Society
ERJ Open Research, Vol 7, Iss 2 (2021)
ERJ Open Research, 7(2):00731-2020. BMJ Publishing Group
ERJ Open Research
article-version (VoR) Version of Record
ERJ open research, 7(2):00731-2020. European Respiratory Society
ERJ Open Research, Vol 7, Iss 2 (2021)
Rationale Targeted cystic fibrosis (CF) therapy with lumacaftor/ivacaftor partly restores chloride channel function and improves epithelial fluid transport in the airways. Consequently, changes may occur in the microbiome, which is adapted to CF lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab579d0ee582c686532e1520e3205a9
https://research.vumc.nl/en/publications/cdb44a8a-7c3d-44d5-8941-b1e909993ffb
https://research.vumc.nl/en/publications/cdb44a8a-7c3d-44d5-8941-b1e909993ffb
Autor:
Luis J. V. Galietta, Alan S. Verkman
Publikováno v:
Am J Physiol Cell Physiol
Chloride transport across cell membranes is broadly involved in epithelial fluid transport, cell volume and pH regulation, muscle contraction, membrane excitability, and organellar acidification. The human genome encodes at least 53 chloride-transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1543d230b64a64444322e41fcfa8bd1c
http://hdl.handle.net/11588/863065
http://hdl.handle.net/11588/863065
Publikováno v:
American Journal of Otolaryngology. 39:737-740
Background Cystic Fibrosis is an autosomal recessive disorder with a mutation in the cystic fibrosis transmembrane regulator gene, leading to dysregulation of epithelial fluid transport, dehydration of airway surfaces and impaired mucociliary functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2e658e2e5816aaf4aad1241d15e41c
https://doi.org/10.1016/j.amjoto.2018.08.002
https://doi.org/10.1016/j.amjoto.2018.08.002
Autor:
Steffen S. Madsen, Andreas M. Nielsen, Jes Dreier, Laura V. Ellis, Jonathan R. Brewer, Thomas Andersen, Maryline C. Bossus, Christian K. Tipsmark, Christina Baun
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1853 (2020)
Tipsmark, C K, Nielsen, A M, Bossus, M C, Ellis, L V, Baun, C, Andersen, T L, Dreier, J, Brewer, J R & Madsen, S S 2020, ' Drinking and water handling in the medaka intestine : A possible role of claudin-15 in paracellular absorption? ', International Journal of Molecular Sciences, vol. 21, no. 5, 1853 . https://doi.org/10.3390/ijms21051853
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1853 (2020)
Tipsmark, C K, Nielsen, A M, Bossus, M C, Ellis, L V, Baun, C, Andersen, T L, Dreier, J, Brewer, J R & Madsen, S S 2020, ' Drinking and water handling in the medaka intestine : A possible role of claudin-15 in paracellular absorption? ', International Journal of Molecular Sciences, vol. 21, no. 5, 1853 . https://doi.org/10.3390/ijms21051853
When euryhaline fish move between fresh water (FW) and seawater (SW), the intestine undergoes functional changes to handle imbibed SW. In Japanese medaka, the potential transcellular aquaporin-mediated conduits for water are paradoxically downregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab94d0203a36c1da3871c0aa57730cb
https://doi.org/10.3390/ijms21051853
https://doi.org/10.3390/ijms21051853
Autor:
Coen C. Paulusma, Marianne Carlon, Hugo R. de Jonge, Kam S. Ho-Mok, Dragana Vidovic, Jung-Chin Chang, Vincent A. van der Mark, Ronald P.J. Oude Elferink, Suzanne Duijst
Publikováno v:
Biochimica et Biophysica Acta, 1863(9), 2280
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1863(9), 2280-2288. Elsevier
Biochimica et Biophysica Acta-Molecular Cell Research, 1863(9), 2280-2288. Elsevier
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1863(9), 2280-2288. Elsevier
Biochimica et Biophysica Acta-Molecular Cell Research, 1863(9), 2280-2288. Elsevier
Progressive familial intrahepatic cholestasis type 1 (PFIC1) is caused by mutations in the gene encoding the phospholipid flippase ATP8B1. Apart from severe cholestatic liver disease, many PFIC1 patients develop extrahepatic symptoms characteristic o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8645138071e20f6b16b88e8047c8c051
https://hdl.handle.net/1765/97114
https://hdl.handle.net/1765/97114
Publikováno v:
Anesthesiology. 122:1084-1092
Background: Patients with acute respiratory distress syndrome who retain maximal alveolar fluid clearance (AFC) have better clinical outcomes. The release of endogenous catecholamines associated with shock or the administration of β2-adrenergic rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d64ca6ea0d8f1dfd42a9f66ded76863
https://doi.org/10.1097/aln.0000000000000595
https://doi.org/10.1097/aln.0000000000000595
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