Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Epithelial Cells / pathology"'
Publikováno v:
Llorián-Salvador, M, Byrne, E M, Szczepan, M, Little, K, Chen, M & Xu, H 2022, ' Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells ', Journal of Neuroinflammation, vol. 19, 182 . https://doi.org/10.1186/s12974-022-02546-3
Scientia
Scientia
Background We previously reported higher plasma levels of complement fragments C3a and C5a in neovascular Age-related Macular Degeneration (nAMD) patients with macular fibrosis. This study aimed to understand whether complement activation contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a0980be464afeeb7b4ab315fe1f0e5
http://hdl.handle.net/10230/54663
http://hdl.handle.net/10230/54663
Publikováno v:
The Journal of Pathology: Clinical Research
The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 542-547 (2021)
The journal of pathology. Clinical research, vol. 7, no. 6, pp. 542-547
The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 542-547 (2021)
The journal of pathology. Clinical research, vol. 7, no. 6, pp. 542-547
Image based biomarker discovery typically requires an accurate segmentation of histologic structures (e.g., cell nuclei, tubules, epithelial regions) in digital pathology Whole Slide Images (WSI). Unfortunately, annotating each structure of interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0323329c22d8982925d97e60ffadb41f
http://arxiv.org/abs/2101.02183
http://arxiv.org/abs/2101.02183
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8746, p 8746 (2020)
International Journal of Molecular Sciences, 2020, 21 (22), pp.8746. ⟨10.3390/ijms21228746⟩
International Journal of Molecular Sciences, MDPI, 2020, 21 (22), pp.8746. ⟨10.3390/ijms21228746⟩
International Journal of Molecular Sciences, Vol 21, Iss 8746, p 8746 (2020)
International Journal of Molecular Sciences, 2020, 21 (22), pp.8746. ⟨10.3390/ijms21228746⟩
International Journal of Molecular Sciences, MDPI, 2020, 21 (22), pp.8746. ⟨10.3390/ijms21228746⟩
International audience; Deimination (or citrullination) is a post-translational modification catalyzed by a calcium-dependent enzyme family of five peptidylarginine deiminases (PADs). Deimination is involved in physiological processes (cell different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dea2c1fa620f63c25246da202a39d52b
https://pubmed.ncbi.nlm.nih.gov/33228136
https://pubmed.ncbi.nlm.nih.gov/33228136
Autor:
Hyunglok Chung, Aamir Nazir, Federico Santoni, Alkistis Manousopoulou, Hugo J. Bellen, Khitab Gul, Graeme C.M. Black, Maqsood Ali Ansari, Stylianos E. Antonarakis, Muhammad Ansar, Rachel L. Taylor, Constantin J. Pournaras, Samina Imtiaz, Emilie Falconnet, Jawad Ahmed, Inayat Shah, Sondas Saeed, Periklis Makrythanasis, Michel Guipponi, Muhammad T. Sarwar, Emmanuelle Ranza
Publikováno v:
Taylor, R L & Black, G 2018, ' Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts ', American Journal of Human Genetics, vol. 103, no. 4, pp. 568-578 . https://doi.org/10.1016/j.ajhg.2018.09.004
Infantile and childhood-onset cataracts form a heterogeneous group of disorders; among the many genetic causes, numerous pathogenic variants in additional genes associated with autosomal-recessive infantile cataracts remain to be discovered. We ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dd3f45d6e6b70caf69d2d3b3c7a9c6
https://doi.org/10.1016/j.ajhg.2018.09.004
https://doi.org/10.1016/j.ajhg.2018.09.004
Autor:
Joana Carvalho, Sara Pinto Teles, Carla Oliveira, Patrícia Oliveira, Mafalda Azevedo, Sara Rocha
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2608 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
Extracellular vesicles (EVs) secreted by tumor cells modulate recipient cells&rsquo
behavior, but their effects in normal cells from the tumor microenvironment remain poorly known. In this study, we dissected the functional impact of gastric can
behavior, but their effects in normal cells from the tumor microenvironment remain poorly known. In this study, we dissected the functional impact of gastric can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0217515a50b63b03bf7a49c0de7b6017
https://www.mdpi.com/1422-0067/20/11/2608
https://www.mdpi.com/1422-0067/20/11/2608
Autor:
Anake Kijjoa, Cristina P.R. Xavier, Ricardo J. Fernandes, Emília Sousa, Solida Long, Madalena Pinto, Artur M. S. Silva, Diana I. S. P. Resende, M. Helena Vasconcelos
Publikováno v:
Molecules
Volume 24
Issue 3
Molecules, Vol 24, Iss 3, p 534 (2019)
Volume 24
Issue 3
Molecules, Vol 24, Iss 3, p 534 (2019)
New quinazolinone derivatives of the marine-derived alkaloids fiscalin B (3) and fumiquinazoline G (1), with neuroprotective and antitumor effects, were synthesized. Eleven quinazolinone-containing indole alkaloids were synthesized, proceeding the an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d9a9a606b76108e05d78fd2f7ee112
Autor:
Alfredo Campennì, Frederik A. Verburg, Pierpaolo Trimboli, Massimo Bongiovanni, Luca Ceriani, Giorgio Treglia, L. Giovanella
Publikováno v:
European journal of nuclear medicine and molecular imaging 43(6), 1018-1026 (2016). doi:10.1007/s00259-015-3285-1
European journal of nuclear medicine and molecular imaging, vol. 43, no. 6, pp. 1018-1026
European Journal of Nuclear Medicine and Molecular Imaging
European journal of nuclear medicine and molecular imaging, vol. 43, no. 6, pp. 1018-1026
European Journal of Nuclear Medicine and Molecular Imaging
European journal of nuclear medicine and molecular imaging 43(6), 1018-1026 (2016). doi:10.1007/s00259-015-3285-1
Published by Springer-Verl., Heidelberg [u.a.]
Published by Springer-Verl., Heidelberg [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0578cf8595b55a306898c4c816b0b2
https://doi.org/10.1007/s00259-015-3285-1
https://doi.org/10.1007/s00259-015-3285-1
Autor:
Flemming Brandt Sørensen, G W van Pelt, Rob A. E. M. Tollenaar, J.H.J.M. van Krieken, Hans Morreau, Sanne Kjær-Frifeldt, Wilma E. Mesker, R. al Dieri
Publikováno v:
Virchows Archiv
van Pelt, G W, Kjær-Frifeldt, S, van Krieken, J H J M, Al Dieri, R, Morreau, H, Tollenaar, R A E M, Sørensen, F B & Mesker, W E 2018, ' Scoring the tumor-stroma ratio in colon cancer : procedure and recommendations ', Virchows Archiv, vol. 473, no. 4, pp. 405-412 . https://doi.org/10.1007/s00428-018-2408-z
Virchows Archiv, 473, 405-412
Virchows Archiv, 473, 4, pp. 405-412
Virchows Archiv, 473(4), 405-412
van Pelt, G W, Kjær-Frifeldt, S, van Krieken, J H J M, Al Dieri, R, Morreau, H, Tollenaar, R A E M, Sørensen, F B & Mesker, W E 2018, ' Scoring the tumor-stroma ratio in colon cancer : procedure and recommendations ', Virchows Archiv, vol. 473, no. 4, pp. 405-412 . https://doi.org/10.1007/s00428-018-2408-z
Virchows Archiv, 473, 405-412
Virchows Archiv, 473, 4, pp. 405-412
Virchows Archiv, 473(4), 405-412
The tumor-stroma ratio (TSR) has been reported as a strong, independent prognostic parameter in colon cancer as well as in other epithelial cancer types, and may be implemented to routine pathology diagnostics. The TSR is an easy technique, based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3dd32589339d4b0f3fe5de20421fbc
https://hdl.handle.net/1887/79914
https://hdl.handle.net/1887/79914
Publikováno v:
Deng, Y, Herbert, J A, Smith, C M & Smyth, R L 2018, ' An in vitro transepithelial migration assay to evaluate the role of neutrophils in Respiratory Syncytial Virus (RSV) induced epithelial damage ', Scientific Reports, vol. 8, no. 1, pp. 6777 . https://doi.org/10.1038/s41598-018-25167-4
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Large numbers of neutrophils migrate into the lungs of children with severe Respiratory Syncytial Virus (RSV) disease. It is unclear how these cells contribute to viral clearance and recovery from infection or whether they contribute to disease patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aca1198f865512af4053e70d3d45e1c0
https://doi.org/10.1038/s41598-018-25167-4
https://doi.org/10.1038/s41598-018-25167-4
Autor:
Mari Mino-Kenudson, Brian G. Turner, Ivan Chebib, William R. Brugge, Kurt A. Yaeger, Martha B. Pitman, Muriel Genevay
Publikováno v:
Cancer Cytopathology, Vol. 118, No 6 (2010) pp. 434-440
BACKGROUND: The Sendai guidelines for risk assessment of malignancy in patients with mucinous cysts lists "positive" cytology as a high-risk feature. In the current study, the authors hypothesized that a cytological threshold of high-grade atypical e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4dc985cb3047bd8bb7c4a5b2ce99a72
https://doi.org/10.1002/cncy.20118
https://doi.org/10.1002/cncy.20118