Výsledky vyhledávání - "Epileptogenesis."

Akademický článek

Newer glucose‐lowering drugs reduce the risk of late‐onset seizure and epilepsy: A meta‐analysis

Autor: Udeept Sindhu, Akshay Sharma, Ifrah Zawar, Vineet Punia

Publikováno v: Epilepsia Open, Vol 9, Iss 6, Pp 2528-2536 (2024)

Abstract Newer glucose‐lowering drugs (GLDs) protect against cerebrovascular, neurodegenerative, and neuroinflammatory pathologies. Therefore, we performed a meta‐analysis of randomized controlled trials (RCTs) comparing newer GLDs to placebo tha

Externí odkaz: https://doaj.org/article/a88373c59e744cfb81f6a0d4f33562c5

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Kniha

Neuronal mechanisms of epileptogenesis.

Autor: Roberto Di Maio

Externí odkaz: Kolekce e-knih KNAV

Akademický článek

NLRP3 Inflammasome Inhibition After Pilocarpine-Induced Status Epilepticus Attenuates Chronic Inflammation in Epileptic Mice

Autor: Wang L, Wang K, Chen Y, Zhang X, Xu W, Dong Z, Wang Y

Publikováno v: Journal of Inflammation Research, Vol Volume 17, Pp 6143-6158 (2024)

Lei Wang,1,* Kai Wang,2,* Yuwen Chen,1 Xiaoyu Zhang,1,3 Wenhao Xu,1,3 Zhong Dong,1,3 Yu Wang1,3,4 1Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, 230000, People’s Republic of China

Externí odkaz: https://doaj.org/article/d2f4bd8e589047d28f38c6090c2341e9

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Akademický článek

(+)-Borneol inhibits neuroinflammation and M1 phenotype polarization of microglia in epileptogenesis through the TLR4-NFκB signaling pathway

Autor: Shuo Li, Alhamdu Adamu, Yucai Ye, Fankai Gao, Rulin Mi, Guofang Xue, Zhaojun Wang

Publikováno v: Frontiers in Neuroscience, Vol 18 (2024)

ObjectiveTo investigate the effect of (+)-borneol on neuroinflammation and microglia phenotype polarization in epileptogenesis and its possible mechanism.MethodsBased on mouse models of status epilepticus (SE) induced by pilocarpine, and treated with

Externí odkaz: https://doaj.org/article/a487d98c34fc4153863dfce4e639dff2

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Akademický článek

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Akademický článek

Riluzole attenuates acute neural injury and reactive gliosis, hippocampal-dependent cognitive impairments and spontaneous recurrent generalized seizures in a rat model of temporal lobe epilepsy

Autor: Thomas Kyllo, Dominic Allocco, Laine Vande Hei, Heike Wulff, Jeffrey D. Erickson

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

BackgroundRiluzole exhibits neuroprotective and therapeutic effects in several neurological disease models associated with excessive synaptic glutamate (Glu) release. We recently showed riluzole prevents acute excitotoxic hippocampal neural injury at

Externí odkaz: https://doaj.org/article/29ef8d2cde7442f49c7e3867acbffff8

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Akademický článek

Antiepileptic and anti-inflammatory effects of Lippia multiflora moldenke (Verbenaceae) in mice model of chronic temporal lobe epilepsy induced by pilocarpine

Autor: Joseph Ngaibi, Bigued, Antoine Kavaye Kandeda, Yvette Nguezeye, Tchang Alkali Wangbara, Lamido Gaoudji, Germain Sotoing Taiwe, Elisabeth Ngo Bum

Publikováno v: Heliyon, Vol 10, Iss 20, Pp e39483- (2024)

Lippia multiflora Moldenke (Verbenaceae) is an aromatic plant used as a popular medicine with antidepressant, antispasmodic, antifungal, anti-inflammatory, and antioxidant properties. In this study, we explored the effects of L. multiflora in mice ch

Externí odkaz: https://doaj.org/article/18de0b8f52cd4154b375a1f444f8b2d6

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Akademický článek

Alterations in GABAA receptor-mediated inhibition triggered by status epilepticus and their role in epileptogenesis and increased anxiety

Autor: Vassiliki Aroniadou-Anderjaska, Taiza H. Figueiredo, Marcio De Araujo Furtado, Volodymyr I. Pidoplichko, Lucille A. Lumley, Maria F.M. Braga

Publikováno v: Neurobiology of Disease, Vol 200, Iss , Pp 106633- (2024)

The triggers of status epilepticus (SE) in non-epileptic patients can vary widely, from idiopathic causes to exposure to chemoconvulsants. Regardless of its etiology, prolonged SE can cause significant brain damage, commonly resulting in the developm

Externí odkaz: https://doaj.org/article/a229ad7c53834fcdbd6242c1a93473f7

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