(Neo)Determinismo y reducción explicativa en investigaciones epigenéticas en torno a lo humano y sus implicancias biopolíticas

Autor: Manuel Ignacio Stefanini, Ana Liza Tropea, Nicolás José Lavagnino

Publikováno v: Revista Argentina de Antropología Biológica, Vol 26, Iss 2 (2024)

La epigenética como campo disciplinar de consolidación reciente, al estudiar lo humano trajo consigo promesas de superación del determinismo y la reducción explicativa propios de la corriente gen-centrista de la genética. Sin embargo, al analiza

Externí odkaz: https://doaj.org/article/47402ca6be94469c982788531a0573a9

Single cell epigenomic and transcriptomic analysis uncovers potential transcription factors regulating mitotic/meiotic switch

Autor: Fa-Li Zhang, Yan-Qin Feng, Jing-Ya Wang, Ke-Xin Zhu, Lu Wang, Jia-Mao Yan, Xiu-Xiu Li, Jun-Jie Wang, Wei Ge, Massimo De Felici, Wei Shen

Publikováno v: Cell Death & Disease. 14

In order to reveal the complex mechanism governing the mitotic/meiotic switch in female germ cells at epigenomic and genomic levels, we examined the chromatin accessibility (scATAC-seq) and the transcriptional dynamics (scRNA-seq) in germ cells of mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01753b53e29dca3d03edb1d1b16f459e
https://doi.org/10.1038/s41419-023-05671-w

DNA methylation may affect beef tenderness through signal transduction in Bos indicus

Autor: Marcela Maria de Souza, Simone Cristina Méo Niciura, Marina Ibelli Pereira Rocha, Zhangyuan Pan, Huaijun Zhou, Jennifer Jessica Bruscadin, Wellison Jarles da Silva Diniz, Juliana Afonso, Priscila Silva Neubern de Oliveira, Gerson B. Mourão, Adhemar Zerlotini, Luiz Lehmann Coutinho, James E. Koltes, Luciana Correia de Almeida Regitano

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Epigenetics & chromatin, vol 15, iss 1

Background Beef tenderness is a complex trait of economic importance for the beef industry. Understanding the epigenetic mechanisms underlying this trait may help improve the accuracy of breeding programs. However, little is known about epigenetic ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636fa4fe301c3ef528c425f12c0bb1fd

design of CRISPR/dCas9 modular system using orthogonal Cas9 proteins and its application in epigenetic manipulation of gene loci

Autor: Josipović, Goran

Otkrivanje uzročno posljedičnih veza između epigenetičkih oznaka u kromatinu i regulacije ekspresije gena omogućeno je primjenom molekularnih alata koji mogu ciljano mijenjati epigenom. U ovom istraživanju izradio sam modularni sustav temeljen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3908::f988f3161658236f183632fb5f607cbf
https://repozitorij.pmf.unizg.hr/islandora/object/pmf:9690/datastream/PDF

Integración multi-ómica y aprendizaje automático para la identificación de marcadores moleculares de resistencia a la insulina en niños prepúberes y púberes con obesidad

Autor: Anguita Ruiz, Augusto Miguel

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname

THE PRESENT DOCTORAL THESIS WAS FUNDED BY THE FOLLOWING INSTITUTIONS: - Institute of Health Carlos III - Personal funding: “Contratos i-PFIS: doctorados IIS-empresa en ciencias y tecnologías de la salud de la convocatoria 2017 de la Acción Estrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7a1ad6cb2ba94be10ee17ccf6fd145f1
http://hdl.handle.net/10481/70696