Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Epigenetic enzymes"'
Autor:
Samar Sultan, Sultanh AlMalki
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Foetuses exposed to maternal gestational diabetes (GDM) and type 2 diabetes (T2D) have an increased risk of adverse perinatal outcomes. Epigenetic mechanisms, including DNA methylation and histone modifications, may act as mediators of persistent met
Externí odkaz:
https://doaj.org/article/cabecb59bf3b43b791ec5acb2578e2cb
Akademický článek
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Autor:
Gastón Barbero, Maximiliano G. de Sousa Serro, Camila Perez Lujan, Alfredo D. Vitullo, Candela R. González, Betina González
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Accumulating evidence points out that sperm carry epigenetic instructions to embryo in the form of retained histones marks and RNA cargo that can transmit metabolic and behavioral traits to offspring. However, the mechanisms behind epigenetic inherit
Externí odkaz:
https://doaj.org/article/a9ea83a2d0644eba8d737b278e003a0b
Publikováno v:
BioImpacts, Vol 11, Iss 3, Pp 173-179 (2021)
Introduction: Histone modifying enzymes include several classes of enzymes that are responsible for various post-translational modifications of histones such as methylation and acetylation. They are important epigenetic factors, which may involve sev
Externí odkaz:
https://doaj.org/article/27ac0b1800c5465094e753b0a24959ee
Autor:
Alexis Ruiz, Sofia Benucci, Urs Duthaler, Christoph Bachmann, Martina Franchini, Faiza Noreen, Laura Pietrangelo, Feliciano Protasi, Susan Treves, Francesco Zorzato
Publikováno v:
eLife, Vol 11 (2022)
To date there are no therapies for patients with congenital myopathies, muscle disorders causing poor quality of life of affected individuals. In approximately 30% of the cases, patients with congenital myopathies carry either dominant or recessive m
Externí odkaz:
https://doaj.org/article/b1a6c6efb1f14c3480eb8053a31a9386
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 749-764 (2020)
DNA methyltransferase 1 (DNMT1), a large multidomain enzyme, is believed to be involved in the passive transmission of genomic methylation patterns via methylation maintenance. Yet, the molecular mechanism of interaction networks underlying DNMT1 str
Externí odkaz:
https://doaj.org/article/dde4dae808384a118044408674c1a125
Autor:
Immacolata Maietta, Amparo Martínez-Pérez, Rosana Álvarez, Ángel R. De Lera, África González-Fernández, Rosana Simón-Vázquez
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 824 (2022)
Epigenetic modifications could drive some of the molecular events implicated in proliferation, drug resistance and metastasis of pancreatic ductal adenocarcinoma (PDAC). Thus, epigenetic enzyme inhibitors could be the key to revert those events and t
Externí odkaz:
https://doaj.org/article/bbdd1fc839df4b79a66a8d251d6cb672
Akademický článek
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Akademický článek
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Publikováno v:
European Journal of Therapeutics. 28:219-225
Objective: This study aimed to examine the effects of prenatal stress (PS) induced by dexamethasone exposure on gene expression levels of epigenetic enzymes in hippocampus and cerebral cortex of male rats through relative mRNA levels of histone acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f186cd782fa87f0f3b4e1e431231b5
https://doi.org/10.5152/eurjther.2022.22056
https://doi.org/10.5152/eurjther.2022.22056