Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Epigenesis, Genetic/physiology"'
1
Les rétrovirus endogènes : un rôle clé dans la programmation des lymphocytes T CD4
Autor: Véronique Adoue, Olivier Joffre
Publikováno v: médecine/sciences
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
Upon priming by dendritic cells, naïve CD4 T lymphocytes are exposed to distinct molecular environments depending on the nature of the pathological stimulus. In response, they mobilize different gene networks that establish lineage-specific developm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8bbf56b7f22d0ec282cc76e4db22f
https://doi.org/10.1051/medsci/2020022
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2
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation
Autor: Marianne Burbage, Pablo J. Sáez, Deborah Lefevre, Thomas Hoyler, Amal Zine El Aabidine, Rébecca Panes, Guadalupe Suarez, Christel Goudot, Sebastian Amigorena, Jean-Marie Carpier, Mengliang Ye, Fanny Aprahamian, Claire Hivroz, Florence Cammas, Olivier Joffre, Véronique Adoue, Elina Zueva, Jean-Christophe Andrau, Angelique Bellemare-Pelletier, Sylvère Durand, Leonel Joannas, Etienne Gagnon, Maqbool Muhammad Ahmad, Guido Kroemer, Cyril Esnault, Ulf Gehrmann, Sandrine Heurtebise-Chrétien, Nina Burgdorf
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩
Significance CD4 T cells are major regulators of immune responses against both self and pathogens. Understanding pathways that govern CD4 T cell differentiation and regulation are thus key for the discovery of new immunoregulatory drug targets. Here,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdc87a7d673a9a3997e6fdd23ac6a75
https://hal.archives-ouvertes.fr/hal-02369616/document
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4
Reprogrammation épigénétique des cellules hôtes par Legionella pneumophila
Autor: Rolando, Monica, Rusniok, Christophe, Margueron, Raphael, Buchrieser, Carmen
Publikováno v: médecine/sciences
médecine/sciences, 2013, 29 (10), pp.843-845. ⟨10.1051/medsci/20132910010⟩
médecine/sciences, EDP Sciences, 2013, 29 (10), pp.843-845. ⟨10.1051/medsci/20132910010⟩
International audience; Legionella pneumophila est un bacille à Gram négatif à l'origine d'une infection pulmonaire grave appelée légionellose (ou maladie du légionnaire) [11]. Les légionelles sont des bactéries vivant en milieu aquatique et
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1bc686121dd9d7a51e5daf8f1137d472
https://hal-pasteur.archives-ouvertes.fr/pasteur-01331725/document
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5
Host epigenetic targeting by Legionella pneumophila
Autor: Carmen Buchrieser, Christophe Rusniok, Raphaël Margueron, Monica Rolando
Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2013, 29 (10), pp.843-845. ⟨10.1051/medsci/20132910010⟩
médecine/sciences, 2013, 29 (10), pp.843-845. ⟨10.1051/medsci/20132910010⟩
International audience; Legionella pneumophila est un bacille à Gram négatif à l'origine d'une infection pulmonaire grave appelée légionellose (ou maladie du légionnaire) [11]. Les légionelles sont des bactéries vivant en milieu aquatique et
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c500ab0605f457c9fcacb5d87e782f5e
https://hal-pasteur.archives-ouvertes.fr/pasteur-01331725/document
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6
Evidence for biological roots in the transgenerational transmission of intimate partner violence
Autor: Guillaume L. Poirier, Vandana Veenit, Basira Salehi, Maria Isabel Cordero, François Ansermet, Carmen Sandi, Cristina Márquez, X Fontana
Publikováno v: Translational Psychiatry, Vol. 2 (2012) P. e106
Translational Psychiatry
Intimate partner violence is a ubiquitous and devastating phenomenon for which effective interventions and a clear etiological understanding are still lacking. A major risk factor for violence perpetration is childhood exposure to violence, prompting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9889e8cf75ba4387381d5b1a06b75972
https://archive-ouverte.unige.ch/unige:43586
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7
Polo-like kinase 2 (SNK/PLK2) is a novel epigenetically regulated gene in acute myeloid leukemia and myelodysplastic syndromes: genetic and epigenetic interactions
Autor: Tim Crook, Leonidas Benetatos, Eleftheria Hatzimichael, Konstantinos L. Bourantas, Aggeliki Dasoula, George Dranitsaris, Nelofer Syed, Maria Voukelatou
Publikováno v: Annals of hematology. 90(9)
Polo-like kinase 2 (SNK/PLK2), a transcriptional target for wild-type p53 and is hypermethylated in a high percentage of multiple myeloma and B cell lymphomas patients. Given these data, we sought to study the methylation status of the specific gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eaa763fa9b06835a6e6c079677c17b
https://pubmed.ncbi.nlm.nih.gov/21340720
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8
De l'épigénétique et du développement
Autor: Cederroth, C. R., Vassalli, Jean-Dominique, Nef, Serge
Publikováno v: Revue médicale suisse, Vol. 3, No 100 (2007) pp. 528, 530-522
Epigenetics is defined as the study of the heritable changes in gene expression that are transmitted from a mother cell to a daughter cell or a parent to its progeny, that occur without modifications in DNA sequences. The epigenetic mechanisms of gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::8bc662a920ed4b27c173c4decf035908
https://archive-ouverte.unige.ch/unige:9152
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9
Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis
Autor: Hamish S. Scott, P E Crewther, Pärt Peterson, Stylianos E. Antonarakis, Robert Lyle, Ulla Aapola, David M. de Kretser, Stephen J. Fletcher, Mark P. Hedger, D. K. Harrison, Nawapen Phutikanit, Moira K O'Bryan, Sarah J Meachem, Hnin Thanda Aung, Jeffrey M. Craig, Bernard J. Carroll, Kylie E. Webster
Publikováno v: Proceedings of the National Academy of Sciences, Vol. 102, No 11 (2005) pp. 4068-4073
The production of mature germ cells capable of generating totipotent zygotes is a highly specialized and sexually dimorphic process. The transition from diploid primordial germ cell to haploid spermatozoa requires genome-wide reprogramming of DNA met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe123455cffd02e44657c3724056507d
https://pubmed.ncbi.nlm.nih.gov/15753313
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