Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Epidermal growth factor receptor pathway"'
Autor:
Eun-Hye Joo, Jai Hee Bae, Jihye Park, Yoon Ji Bang, Joseph Han, Nicholas Gulati, Jong-Il Kim, Chung-Gyu Park, Woong-Yang Park, Hyun Je Kim
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adult T-cell Leukemia/Lymphoma (ATLL) is a rare aggressive T-cell malignancy caused by human T-cell leukemia virus type 1 (HTLV-1) infection. However, little is known about the underlying activated molecular pathways at the single cell level. Moreove
Externí odkaz:
https://doaj.org/article/b60aa5d49940473c808a5c2db3f6ea90
Autor:
Meifang Li, Jilong Yang, Lenghe Zhang, Sanfang Tu, Xuan Zhou, Ze Tan, Weijun Zhou, Yanjie He, Yuhua Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background Epidermal growth factor receptor (EGFR) and epidermal growth factor receptor pathway substrate 8 (Eps8) have been widely reported to be expressed in various tumors. Eps8 is an important active kinase substrate of EGFR that directl
Externí odkaz:
https://doaj.org/article/22e6a81e5ea3451cb6c1d658b83031dc
Autor:
Yanyan Tang, Rui Tang, Mengtian Tang, Ping Huang, Zhiqiang Liao, Jumei Zhou, Lianqing Zhou, Min Su, Pan Chen, Jiarui Jiang, Yingbin Hu, Yujuan Zhou, QianJin Liao, Zhaoyang Zeng, Wei Xiong, Junhong Chen, Shaolin Nie
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Colorectal cancer (CRC) is one of the most common cancers worldwide. Recent studies have shown that long non-coding RNAs (lncRNAs) are involved in tumorigenesis and the development of CRC. By constructing a differential lncRNA expression profile, we
Externí odkaz:
https://doaj.org/article/99f2f86da7904d9dba2d5bea860bd660
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect. Here, we describe the role of EPS8 in acute myeloid leu
Externí odkaz:
https://doaj.org/article/48bcaf0359dc447f88b6228818f398e2
Publikováno v:
Oncology Reports
Epidermal growth factor receptor pathway substrate 8 (Eps8) was initially identified as the substrate for the kinase activity of EGFR, improving the responsiveness of EGF, which is involved in cell mitosis, differentiation and other physiological fun
Publikováno v:
Anti-Cancer Drugs
Esophageal cancer is one of the fatal cancers around the world. Dexmedetomidine (DEX) is widely used during anesthesia of esophageal cancer surgery. Nevertheless, the role of DEX in the progression of esophageal cancer remains barely known. The proli
Autor:
Reynaldo L. Garcia, Arlou Kristina J. Angeles, Ryan Timothy D. Yu, Eva Maria Cutiongco de la Paz
Publikováno v:
Oncology Letters
KRAS proto-oncogene, GTPase (KRAS) functions as a molecular switch at the apex of multiple signaling pathways controlling cell proliferation, differentiation, migration, and survival. Canonical KRAS mutants, such as those in codons 12 and 13, produce
Autor:
Jilong Yang, Yuhua Li, Xuan Zhou, Ze Tan, Sanfang Tu, Weijun Zhou, Meifang Li, Yanjie He, Lenghe Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Epidermal growth factor receptor (EGFR) and epidermal growth factor receptor pathway substrate 8 (Eps8) have been widely reported to be expressed in various tumors. Eps8 is an important active kinase substrate of EGFR that directly binds t
Publikováno v:
Turkish Journal of Biochemistry. 44:62-69
BackgroundMalignant mesothelioma (MM) is an endemic disease around central Anatolia region in Turkey, where people are exposed to erionite- and asbestos-contaminated soil. Aberrant EGFR signalling has implicated in several cancers including MMs. Tyro
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