Autophagy inhibition blunts PDGFRA adipose progenitors' cell-autonomous fibrogenic response to high-fat diet

Autor: Nadine Suffee, Geneviève Marcelin, Emmanuel L. Gautier, Amélie Lacombe, Carla Da Cunha, Isabelle Dugail, Christine Rouault, Nataliya Sokolovska, Karine Clément, Arnaud Leclerc, Camille Gamblin

Publikováno v: Autophagy
Autophagy, 2020, 16 (12), pp.2156-2166. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, 2020, 16 (12), Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩
Autophagy, Taylor & Francis, 2020, Epub ahead of print. ⟨10.1080/15548627.2020.1717129⟩

International audience; Adipose tissue (AT) fibrosis in obesity compromises adipocyte functions and responses to intervention-induced weight loss. It is driven by AT progenitors with dual fibro/adipogenic potential, but pro-fibrogenic pathways activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12def550e67c96ae654a1b812d9d43f
https://pubmed.ncbi.nlm.nih.gov/31992125