Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Ephrin A5"'
Autor:
Yoji Kishi, Yoshinori Ino, Mari Shimasaki, Toshimitsu Iwasaki, Kazuaki Shimada, Kosei Nakajima, Nobuyoshi Hiraoka, Minoru Esaki, Utako Ishimoto, Satoshi Nara, Noriteru Doi, Chie Naito
Publikováno v:
Br J Cancer
BACKGROUND: The treatment of pancreatic cancer (PDAC) remains clinically challenging, and neoadjuvant therapy (NAT) offers down staging and improved surgical resectability. Abundant fibrous stroma is involved in malignant characteristic of PDAC. We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce436f47ec73e11b683d8a5021a4963
https://doi.org/10.1038/s41416-021-01639-9
https://doi.org/10.1038/s41416-021-01639-9
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Retinal neovascularization (RNV) is an important pathological feature of vitreoretinopathy that can lead to severe vision loss. The purpose of this study was to identify the role of ephrin-A5 (Efna5) in RNV and to explore its mechanism. The expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8500bc4ab8c63047186458b31221ba86
https://doi.org/10.1155/2020/7161027
https://doi.org/10.1155/2020/7161027
Publikováno v:
European Journal of Pharmacology. 917:174588
Gliomas, tumors of glial cells, are the most common malignant tumors of the brain. Ephrins are protein ligands that act through tyrosine kinases receptor family, Eph receptors. In glioma, an inverse relationship has been identified between ephrin A1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5541e1d55ffe77a986a085d47831f684
https://doi.org/10.1016/j.ejphar.2021.174588
https://doi.org/10.1016/j.ejphar.2021.174588
Autor:
Lu Xu, Alan D. Flechtner, L. James Lee, Qiwen Shen, Paolo Fadda, Lianbo Yu, Jessica M. Marbourg, Rumana Yasmeen, Phillip G. Popovich, Ouliana Ziouzenkova
Publikováno v:
Translational Research. 192:1-14
Innervation is a fundamental basis for function and survival of tissues. In the peripheral tissues, degenerative diseases create a neurotoxic metabolic milieu that either causes neurodegeneration or fails to sustain regenerative growth and reinnervat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de10ae9e23b66f909e9d64aa2b322729
https://doi.org/10.1016/j.trsl.2017.10.005
https://doi.org/10.1016/j.trsl.2017.10.005
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Axonal growth cones are guided by molecular cues in the extracellular environment. The mechanisms of combinatorial integration of guidance signals at the growth cone cell membrane are still being unravelled. Limb-innervating axons of vertebrate spina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdcce1d25825d5f520f4497f21fea2f
https://doi.org/10.1038/s41598-019-48519-0
https://doi.org/10.1038/s41598-019-48519-0
Autor:
Albert C. Ludolph, Jochen H. Weishaupt, Philip Van Damme, Annette Lenaerts, Wim Robberecht, Jasmijn van der Vos, Silke Smolders, Laura Rué, Patrick Oeckl, Ludo Van Den Bosch, Antina de Boer, Lindsay Poppe, Mieke Timmers, Robin Lemmens, Markus Otto
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects motor neurons in the brainstem, spinal cord and motor cortex. ALS is characterized by genetic and clinical heterogeneity, suggesting the existence of genetic factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3999b4f7642b8bc4a85ad649a1c41343
https://lirias.kuleuven.be/handle/123456789/644713
https://lirias.kuleuven.be/handle/123456789/644713
Autor:
Yuhan Hu, Annika G. Samuelson, Alexandra Magee, Laura Anne Lowery, Garrett M. Cammarata, Paula G. Slater
Publikováno v:
J Cell Sci
It has long been established that neuronal growth cone navigation depends on changes in microtubule (MT) and F-actin architecture downstream of guidance cues. However, the mechanisms by which MTs and F-actin are dually coordinated remain a fundamenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481b06ec873007340df32b05c183944f
https://doi.org/10.1242/jcs.224311
https://doi.org/10.1242/jcs.224311
Publikováno v:
Genes, Brain and Behavior. 16:271-284
During development of the nervous system, molecular signals mediating cell-cell interactions play critical roles in the guidance of axonal growth and establishment of synaptic functions. The Eph family of tyrosine kinase receptors and their ephrin li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::814a1816409f31daef691d1408f0c218
https://doi.org/10.1111/gbb.12319
https://doi.org/10.1111/gbb.12319
Publikováno v:
Oncotarget
// Sara Ferluga 1 , Carla Maria Lema Tome 2 , Denise Mazess Herpai 1 , Ralph D’Agostino 3 , Waldemar Debinski 1 1 Department of Cancer Biology, Radiation Oncology and Neurosurgery, Brain Tumor Center of Excellence, Comprehensive Cancer Center of Wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f8239ca6301cfa2f7c08935d17c60d
http://europepmc.org/articles/PMC5312354
http://europepmc.org/articles/PMC5312354
Autor:
Derek C. Adams, Klas Kullander, Leif Oxburgh, Rüdiger Klein, Christiane Peuckert, Pavlo Holenya, Smitha Sreedharan, Bejan Aresh, Annika Porthin, Louise Andersson, Stefan Wölfl, H. Pettersson
Publikováno v:
Kidney International. 90:373-388
A substantial portion of the human population is affected by urogenital birth defects resulting from a failure in ureter development. Although recent research suggests roles for several genes in facilitating the ureter/bladder connection, the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc103a223538a62679caa5eeeff3d28
https://doi.org/10.1016/j.kint.2016.04.021
https://doi.org/10.1016/j.kint.2016.04.021