Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ephraim A. Ansa-Addo"'
Autor:
Don C. Rockey, Serhan Karvar, Lixin Zhu, Zihai Li, Ephraim A. Ansa-Addo, Jo Suda, Shweta Singh
Publikováno v:
Hepatology. 72:1073-1084
Background and aims Moesin, an ezrin/radixin/moesin family member, is involved in the regulation of cell adhesion, polarity, and migration by cross-linking between the actin cytoskeleton and plasma membrane. The primary effector cell in hepatic fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea621bab289067561da95afb3b742746
https://doi.org/10.1002/hep.31078
https://doi.org/10.1002/hep.31078
Publikováno v:
Immunity. 54:395-396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e8950e76d552f770c037488732f665
https://doi.org/10.1016/j.immuni.2021.02.007
https://doi.org/10.1016/j.immuni.2021.02.007
Autor:
Supinya Iamsawat, Dongjun Chung, Philip H. Howe, Jin Hyun Nam, Caroline C. Philpott, Xue-Zhong Yu, Chrystal M. Paulos, Huai-Cheng Huang, Brian Riesenberg, Michelle H. Nelson, Bei Liu, Davis Borucki, Ephraim A. Ansa-Addo, Zihai Li
Publikováno v:
Science Advances
RNA binding protein PCBP1 guards effector and antitumor T cell functions.
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Here, we identify the RNA binding pro
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Here, we identify the RNA binding pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f87693223e021fb3167f49b74ff8d17
https://pubmed.ncbi.nlm.nih.gov/32523987
https://pubmed.ncbi.nlm.nih.gov/32523987
Autor:
Brian Riesenberg, Jennifer Gutierrez, Bei Liu, Cynthia Timmers, Ephraim A. Ansa-Addo, Zihai Li
Publikováno v:
J Immunol
Aside from their roles in hemostasis and thrombosis, thrombocytes or platelets also promote tumor growth via immune suppression. However, the extent to which platelet activation shapes the immunosuppressive tumor microenvironment (TME) and whether pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b8c6a74ace5b0509f1266b20defc31
https://europepmc.org/articles/PMC7304159/
https://europepmc.org/articles/PMC7304159/
Autor:
Alessandra Metelli, Ephraim A. Ansa-Addo, Shaoli Sun, Bei Liu, Zihai Li, Yongliang Zhang, Mohammad Salem, Hyunwoo Kwon, Bill X. Wu, Silvia Guglietta, Maria Velegraki, Brian Riesenberg, Caroline Wallace, Anqi Li
Activated regulatory T (Treg) cells express the surface receptor glycoprotein-A repetitions predominant (GARP), which binds and activates latent TGFβ. How GARP modulates Treg function in inflammation and cancer remains unclear. Here we demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14119e0c6e0ea251fb704fed2a08e764
https://europepmc.org/articles/PMC6420855/
https://europepmc.org/articles/PMC6420855/
Autor:
Supinya Iamsawat, Chrystal M. Paulos, Caroline C. Philpott, Xue-Zhong Yu, Bei Liu, Michelle H. Nelson, Jin Hyun Nam, Davis Borucki, Dongjun Chung, Philip H. Howe, Brian Riesenberg, Huai-Cheng Huang, Zihai Li, Ephraim A. Ansa-Addo
Publikováno v:
SSRN Electronic Journal.
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Immunotherapy involving the block of cell surface immune checkpoints CTLA-4 and PD-1/PD-L1 has revolutionized treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfb86609e3b2bda473587d0b2d514b2
https://doi.org/10.2139/ssrn.3418426
https://doi.org/10.2139/ssrn.3418426
Autor:
Mark J. Shlomchik, Zihai Li, Caroline Wallace, Alessandra Metelli, Shaoli Sun, Mohammad Salem, Gary S. Gilkeson, Ephraim A. Ansa-Addo, Bei Liu, Bill X. Wu
Publikováno v:
JCI insight. 3(7)
GARP, a cell surface docking receptor for binding and activating latent TGF-β, is highly expressed by platelets and activated Tregs. While GARP is implicated in immune invasion in cancer, the roles of the GARP-TGF-β axis in systemic autoimmune dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cec3ee8d38f5e0e51d7f17356b896b
https://pubmed.ncbi.nlm.nih.gov/29618665
https://pubmed.ncbi.nlm.nih.gov/29618665
Autor:
Chenthamarakshan Vasu, Ephraim A. Ansa-Addo, Alessandra Metelli, Feng Hong, Bei Liu, Bill X. Wu, Shaoli Sun, Zihai Li, Yongliang Zhang, Yi Yang, Jessica E. Thaxton, Saleh Rachidi
Publikováno v:
Journal of Clinical Investigation. 125:859-869
Molecular chaperones control a multitude of cellular functions via folding chaperone-specific client proteins. CD4+FOXP3+ Tregs play key roles in maintaining peripheral tolerance, which is subject to regulation by multiple molecular switches, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97d8f8e765766e676e6bf1c7bec0712
https://doi.org/10.1172/jci79014
https://doi.org/10.1172/jci79014
Autor:
Ephraim Abrokwa Ansa-Addo, Huai-Cheng Huang, Supinya Iamsawat, Xue-Zhong Yu, Philip H Howe, Zihai Li
Publikováno v:
The Journal of Immunology. 202:57.12-57.12
Maintaining adequate regulatory T cell (Treg) and effector T cell balance is critical for efficient regulation of tolerance and immune response, respectively. There is increasing evidence that in addition to regulating RNA fate, RNA-binding proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f2c42a61ecbb1fc5505f7371f82d93
https://doi.org/10.4049/jimmunol.202.supp.57.12
https://doi.org/10.4049/jimmunol.202.supp.57.12
Publikováno v:
Biochemical Society Transactions. 41:258-262
The release of extracellular vesicles, whether MVs (microvesicles) or exosomes, from host cells or intracellular pathogens is likely to play a significant role in the infection process. Host MVs may fuse with pathogen surfaces to deliver host complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66258f1cb0612afcbc8086b9a829cd5
https://doi.org/10.1042/bst20120257
https://doi.org/10.1042/bst20120257