Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ephraim A. Ansa‐Addo"'
Autor:
Ephraim A. Ansa‐Addo, Paras Pathak, Maria V. McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I. Ramirez, Jameel M. Inal
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract During cell invasion, large Extracellular Vesicle (lEV) release from host cells was dose‐dependently triggered by Trypanosoma cruzi metacyclic trypomastigotes (Mtr). This lEV release was inhibited when IP3‐mediated Ca2+ exit from the ER
Externí odkaz:
https://doaj.org/article/3fd58d97f3924d10b24848b3ac203071
Autor:
Ephraim A. Ansa-Addo, Yu Wang, Joal D. Beane, Han Wang, Allan Tsung, Hai Huang, Yujia Xia, Dean Tian, Chengli Shen, Zheng Huang, Zachary J. Brown, Hongji Zhang, Zhiwei Hu
Publikováno v:
Journal of Hepatology. 75:1271-1283
Background & Aims Regulatory T-cells (Tregs) impair cancer immunosurveillance by creating an immunosuppressive environment that fosters tumor cell survival. Our previous findings demonstrated that neutrophil extracellular traps (NETs), which are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295e5590f3194c284967d2a5cf874643
https://doi.org/10.1016/j.jhep.2021.07.032
https://doi.org/10.1016/j.jhep.2021.07.032
Autor:
Don C. Rockey, Serhan Karvar, Lixin Zhu, Zihai Li, Ephraim A. Ansa-Addo, Jo Suda, Shweta Singh
Publikováno v:
Hepatology. 72:1073-1084
Background and aims Moesin, an ezrin/radixin/moesin family member, is involved in the regulation of cell adhesion, polarity, and migration by cross-linking between the actin cytoskeleton and plasma membrane. The primary effector cell in hepatic fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea621bab289067561da95afb3b742746
https://doi.org/10.1002/hep.31078
https://doi.org/10.1002/hep.31078
Publikováno v:
Immunity. 54:395-396
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e8950e76d552f770c037488732f665
https://doi.org/10.1016/j.immuni.2021.02.007
https://doi.org/10.1016/j.immuni.2021.02.007
Autor:
Supinya Iamsawat, Dongjun Chung, Philip H. Howe, Jin Hyun Nam, Caroline C. Philpott, Xue-Zhong Yu, Chrystal M. Paulos, Huai-Cheng Huang, Brian Riesenberg, Michelle H. Nelson, Bei Liu, Davis Borucki, Ephraim A. Ansa-Addo, Zihai Li
Publikováno v:
Science Advances
RNA binding protein PCBP1 guards effector and antitumor T cell functions.
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Here, we identify the RNA binding pro
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Here, we identify the RNA binding pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f87693223e021fb3167f49b74ff8d17
https://pubmed.ncbi.nlm.nih.gov/32523987
https://pubmed.ncbi.nlm.nih.gov/32523987
Autor:
Brian Riesenberg, Jennifer Gutierrez, Bei Liu, Cynthia Timmers, Ephraim A. Ansa-Addo, Zihai Li
Publikováno v:
J Immunol
Aside from their roles in hemostasis and thrombosis, thrombocytes or platelets also promote tumor growth via immune suppression. However, the extent to which platelet activation shapes the immunosuppressive tumor microenvironment (TME) and whether pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b8c6a74ace5b0509f1266b20defc31
https://europepmc.org/articles/PMC7304159/
https://europepmc.org/articles/PMC7304159/
Autor:
Alessandra Metelli, Ephraim A. Ansa-Addo, Shaoli Sun, Bei Liu, Zihai Li, Yongliang Zhang, Mohammad Salem, Hyunwoo Kwon, Bill X. Wu, Silvia Guglietta, Maria Velegraki, Brian Riesenberg, Caroline Wallace, Anqi Li
Activated regulatory T (Treg) cells express the surface receptor glycoprotein-A repetitions predominant (GARP), which binds and activates latent TGFβ. How GARP modulates Treg function in inflammation and cancer remains unclear. Here we demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14119e0c6e0ea251fb704fed2a08e764
https://europepmc.org/articles/PMC6420855/
https://europepmc.org/articles/PMC6420855/
Autor:
Supinya Iamsawat, Chrystal M. Paulos, Caroline C. Philpott, Xue-Zhong Yu, Bei Liu, Michelle H. Nelson, Jin Hyun Nam, Davis Borucki, Dongjun Chung, Philip H. Howe, Brian Riesenberg, Huai-Cheng Huang, Zihai Li, Ephraim A. Ansa-Addo
Publikováno v:
SSRN Electronic Journal.
Distinct lineages of T cells can act in response to various environmental cues to either drive or restrict immune-mediated pathology. Immunotherapy involving the block of cell surface immune checkpoints CTLA-4 and PD-1/PD-L1 has revolutionized treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfb86609e3b2bda473587d0b2d514b2
https://doi.org/10.2139/ssrn.3418426
https://doi.org/10.2139/ssrn.3418426
Autor:
Mark J. Shlomchik, Zihai Li, Caroline Wallace, Alessandra Metelli, Shaoli Sun, Mohammad Salem, Gary S. Gilkeson, Ephraim A. Ansa-Addo, Bei Liu, Bill X. Wu
Publikováno v:
JCI insight. 3(7)
GARP, a cell surface docking receptor for binding and activating latent TGF-β, is highly expressed by platelets and activated Tregs. While GARP is implicated in immune invasion in cancer, the roles of the GARP-TGF-β axis in systemic autoimmune dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cec3ee8d38f5e0e51d7f17356b896b
https://pubmed.ncbi.nlm.nih.gov/29618665
https://pubmed.ncbi.nlm.nih.gov/29618665
Autor:
Chenthamarakshan Vasu, Ephraim A. Ansa-Addo, Alessandra Metelli, Feng Hong, Bei Liu, Bill X. Wu, Shaoli Sun, Zihai Li, Yongliang Zhang, Yi Yang, Jessica E. Thaxton, Saleh Rachidi
Publikováno v:
Journal of Clinical Investigation. 125:859-869
Molecular chaperones control a multitude of cellular functions via folding chaperone-specific client proteins. CD4+FOXP3+ Tregs play key roles in maintaining peripheral tolerance, which is subject to regulation by multiple molecular switches, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97d8f8e765766e676e6bf1c7bec0712
https://doi.org/10.1172/jci79014
https://doi.org/10.1172/jci79014