Zobrazeno 1 - 10
of 167
pro vyhledávání: '"EphA"'
Autor:
Anqi Wang, Jianjie Zhu, Yue Li, Min Jiao, Saiqun Zhang, Zong-li Ding, Jian-an Huang, Zeyi Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The EphA family belongs to a large group of membrane receptor tyrosine kinases. Emerging evidence indicates that the EphA family participates in tumour occurrence and progression. Nonetheless, the expression patterns and prognostic values of
Externí odkaz:
https://doaj.org/article/257bd1193dc4489f813e92838b8b6e01
Akademický článek
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Autor:
Xixun Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundEphAs are a class of ephrin receptors that belong to the membrane-bound receptor tyrosine kinases group. Accumulating experimental evidence has shown that the EphA family is involved in tumor progression, namely in cell proliferation, invas
Externí odkaz:
https://doaj.org/article/4deb776fd94649c681a23009c571a129
Publikováno v:
BMC Cell Biology, Vol 18, Iss 1, Pp 1-20 (2017)
Abstract Background Eph signaling is known to induce contrasting cell behaviors such as promoting and inhibiting cell adhesion/spreading by altering F-actin organization and influencing integrin activities. We have previously demonstrated that EphA2
Externí odkaz:
https://doaj.org/article/0b9611df3f514a3eb002285597c9f381
Autor:
Míriam Javier-Torrent, Sergi Marco, Daniel Rocandio, Maria Pons-Vizcarra, Peter W Janes, Martin Lackmann, Joaquim Egea, Carlos A Saura
Publikováno v:
eLife, Vol 8 (2019)
EphA/ephrin signaling regulates axon growth and guidance of neurons, but whether this process occurs also independently of ephrins is unclear. We show that presenilin-1 (PS1)/γ-secretase is required for axon growth in the developing mouse brain. PS1
Externí odkaz:
https://doaj.org/article/9e21efe51dcd4079bb72e8d40b6a248c
Autor:
Miriam Corrado, Carmine Giorgio, Elisabetta Barocelli, Giuseppe Vittucci Marzetti, Anna Maria Cantoni, Rosanna Di Lecce, Matteo Incerti, Riccardo Castelli, Alessio Lodola, Massimiliano Tognolini
Publikováno v:
Pharmaceuticals, Vol 13, Iss 4, p 69 (2020)
The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorecta
Externí odkaz:
https://doaj.org/article/eb808453faf5442e9d1e55ff869fb247
Autor:
Elise Savier, Michael Reber
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/956474468d784fcda63b12a9f79ddc7e
Autor:
Elise Savier, Stephen J Eglen, Amélie Bathélémy, Martine Perraut, Frank W Pfrieger, Greg Lemke, Michael Reber
Publikováno v:
eLife, Vol 6 (2017)
Sensory processing requires proper alignment of neural maps throughout the brain. In the superficial layers of the superior colliculus of the midbrain, converging projections from retinal ganglion cells and neurons in visual cortex must be aligned to
Externí odkaz:
https://doaj.org/article/2930f5fa39544177ac2f480a2e9a6aae
Autor:
Elisabetta Barocelli, Matteo Incerti, Anna Maria Cantoni, Riccardo Castelli, Carmine Giorgio, Alessio Lodola, Giuseppe Vittucci Marzetti, Massimiliano Tognolini, Rosanna Di Lecce, Miriam Corrado
Publikováno v:
Pharmaceuticals, Vol 13, Iss 69, p 69 (2020)
Pharmaceuticals
Volume 13
Issue 4
Pharmaceuticals
Volume 13
Issue 4
The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorecta
Publikováno v:
Molecules and Cells
Ephrin-A5 has been implicated in the regulation of brain morphogenesis and axon pathfinding. In this study, we used bacterial homologous recombination to express a LacZ reporter in various ephrin-A5 BAC clones to identify elements that regulate ephri