Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eoin P. O'Grady"'
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37611 (2012)
Burkholderia cenocepacia causes chronic and life-threatening respiratory infections in immunocompromized people. The B. cenocepacia N-acyl-homoserine lactone (AHL)-dependent quorum sensing system relies on the production of AHLs by the synthases CepI
Externí odkaz:
https://doaj.org/article/30c48369d5fd46159447eeb6d1b1d5e6
Autor:
Eoin P O'Grady, Pamela A Sokol
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 1 (2011)
Members of the Burkholderia cepacia complex (Bcc) are important in medical, biotechnological and agricultural disciplines. These bacteria naturally occur in soil and water environments and have adapted to survive in association with plants and animal
Externí odkaz:
https://doaj.org/article/f6527d7bae4340ee94afcb8c22a550a1
Publikováno v:
Environmental Microbiology. 15:372-385
Summary Burkholderia cenocepacia is commonly found in the environment and also as an important opportunistic pathogen infecting patients with cystic fibrosis. Successful infection by this bacterium requires coordinated expression of virulence factors
Publikováno v:
Journal of Bacteriology. 193:163-176
Burkholderia cenocepacia is a significant opportunistic pathogen in individuals with cystic fibrosis. ShvR, a LysR-type transcriptional regulator, has previously been shown to influence colony morphology, biofilm formation, virulence in plant and ani
Autor:
Eoin P. O'Grady, Rebecca J. Malott, Silja Inhülsen, Pamela A. Sokol, Leo Eberl, Jessica Toller
Publikováno v:
Journal of bacteriology
Burkholderia cenocepacia utilizes quorum sensing to control gene expression, including the expression of genes involved in virulence. In addition to CepR and CciR, a third LuxR homolog, CepR2, was found to regulate gene expression and virulence facto
Publikováno v:
Nature Reviews Microbiology. 5:337-341
Diverse pathogenic bacteria have developed similar mechanisms to subvert host cell responses. In this Progress article, we focus on bacterial virulence factors with different enzymatic activities that can increase the expression of the Kruppel-like f
Publikováno v:
Infection and Immunity. 74:5893-5902
Pseudomonas aeruginosais an important opportunistic pathogen which is capable of causing both acute and chronic infections in immunocompromised patients. Successful adaptation of the bacterium to its host environment relies on the ability of the orga
Publikováno v:
Infection and Immunity. 74:3012-3015
Posttranscriptional regulation of certain virulence-related genes in Pseudomonas aeruginosa is brought about by RsmA, a small RNA-binding protein. During interaction with airway epithelial cells, RsmA promoted actin depolymerization, cytotoxicity, an
Autor:
Brian Ciruna, Lorne A. Babiuk, Deborah M. Kurrasch, Jennifer V Robertson, Eoin P. O'Grady, W. Ted Allison, Marc Ekker, Vincent Tropepe, Ashley E.E. Bruce, Sarah A. Hutchinson, Sarah J. Childs, Ayoob Ghalami, Tod R. Thiele, Lois Sowden-Plunkett, David Hanwell, Peng Huang, B. Frank Eames, Dan Dragon, Xiao-Yan Wen, Joanna Y. Wilson, Chereen Collymore, Sarah McFarlane, Pierre Drapeau, Rhain P. Louis, Andre G. Buret, Ian C. Scott, Andrew J. Waskiewicz, Marie-Andrée Akimenko, Robert Gerlai, Andrea D. Smida, James J. Dowling
Publikováno v:
Zebrafish. 13:S-153
The zebrafish model system is helping researchers improve the health and welfare of people and animals and has become indispensable for advancing biomedical research. As genetic engineering is both resource intensive and time-consuming, sharing succe
Publikováno v:
Environmental microbiology. 15(2)
Burkholderia cenocepacia is commonly found in the environment and also as an important opportunistic pathogen infecting patients with cystic fibrosis. Successful infection by this bacterium requires coordinated expression of virulence factors, which