Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eoin N Leen"'
Autor:
Eoin N Leen, Frédéric Sorgeloos, Samantha Correia, Yasmin Chaudhry, Fabien Cannac, Chiara Pastore, Yingqi Xu, Stephen C Graham, Stephen J Matthews, Ian G Goodfellow, Stephen Curry
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005509 (2016)
Externí odkaz:
https://doaj.org/article/7ac7ca8752914d04a9921fbb09c5f299
Autor:
Eoin N Leen, Frédéric Sorgeloos, Samantha Correia, Yasmin Chaudhry, Fabien Cannac, Chiara Pastore, Yingqi Xu, Stephen C Graham, Stephen J Matthews, Ian G Goodfellow, Stephen Curry
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005379 (2016)
Translation initiation is a critical early step in the replication cycle of the positive-sense, single-stranded RNA genome of noroviruses, a major cause of gastroenteritis in humans. Norovirus RNA, which has neither a 5´ m7G cap nor an internal ribo
Externí odkaz:
https://doaj.org/article/4511280283ec4f42af6a5f9a7067ed2c
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38723 (2012)
Murine noroviruses have emerged as a valuable tool for investigating the molecular basis of infection and pathogenesis of the closely related human noroviruses, which are the major cause of non-bacterial gastroenteritis. The replication of noroviruse
Externí odkaz:
https://doaj.org/article/bfbf1734208e440db9818493ab186dbb
Publikováno v:
PeerJ, Vol 4, p e1964 (2016)
The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cpro performs most of the proteolytic processing of the polyprotein expressed from the large open reading frame
Externí odkaz:
https://doaj.org/article/94409df438644c1e96d79b6d5460de31
Publikováno v:
PeerJ, Vol 4, p e1964 (2016)
PeerJ
'PeerJ ', vol: 4, pages: e1964-1-e1964-12 (2016)
PeerJ
'PeerJ ', vol: 4, pages: e1964-1-e1964-12 (2016)
The replication of foot-and-mouth disease virus (FMDV) is dependent on the virus-encoded 3C protease (3Cpro). As in other picornaviruses, 3Cproperforms most of the proteolytic processing of the polyprotein expressed from the large open reading frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e32fb3797d1e0fba5ff0d88f5f7a60b
https://peerj.com/articles/1964.pdf
https://peerj.com/articles/1964.pdf
Autor:
Yasmin Chaudhry, Fabien Cannac, Stephen C. Graham, Ian Goodfellow, Stephen Matthews, Chiara Pastore, Samantha Correia, Yingqi Xu, Stephen Curry, Eoin N. Leen, Frédéric Sorgeloos
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 1, p e1005379 (2016)
PLoS Pathogens, 12 (1)
PLoS Pathogens, Vol 12, Iss 1, p e1005379 (2016)
PLoS Pathogens, 12 (1)
Translation initiation is a critical early step in the replication cycle of the positive-sense, single-stranded RNA genome of noroviruses, a major cause of gastroenteritis in humans. Norovirus RNA, which has neither a 5´ m7G cap nor an internal ribo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f90a005cf70c3557f6e519319e7f69
http://europepmc.org/articles/PMC4703368
http://europepmc.org/articles/PMC4703368
Publikováno v:
PeerJ
PeerJ, Vol 3, p e798 (2015)
PeerJ, Vol 3, p e798 (2015)
Noroviruses are positive-sense single-stranded RNA viruses. They encode an NS6 protease that cleaves a viral polyprotein at specific sites to produce mature viral proteins. In an earlier study we obtained crystals of murine norovirus (MNV) NS6 protea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a55a97cbf8bc2bb44209784388fa014
https://pubmed.ncbi.nlm.nih.gov/25755927
https://pubmed.ncbi.nlm.nih.gov/25755927
Autor:
Liliane, Chung, Dalan, Bailey, Eoin N, Leen, Edward P, Emmott, Yasmin, Chaudhry, Lisa O, Roberts, Stephen, Curry, Nicolas, Locker, Ian G, Goodfellow
Publikováno v:
The Journal of Biological Chemistry
Background: Noroviruses use a virus-encoded protein, VPg, covalently linked to the viral RNA for translation. Results: The direct interaction of VPg with the central domain of eIF4G is required for norovirus translation. Conclusion: eIF4G plays a cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8d53ef5b3bf46dbc9302b00c6bc54cf
https://pubmed.ncbi.nlm.nih.gov/24928504
https://pubmed.ncbi.nlm.nih.gov/24928504
Autor:
Chennareddy V. Subba-Reddy, Kim Y. Green, Lisa O. Roberts, Kyr Kwok, JC Young, Lmw Chung, Peter Simpson, Ian Goodfellow, C. C. Kao, Birtley, Yasmin Chaudhry, Stanislav V. Sosnovtsev, Jan Marchant, Stephen Matthews, M Tong, Eoin N. Leen, Sean N. Prater, Stephen Curry
Publikováno v:
Journal of virology. 87(10)
We report the solution structures of the VPg proteins from feline calicivirus (FCV) and murine norovirus (MNV), which have been determined by nuclear magnetic resonance spectroscopy. In both cases, the core of the protein adopts a compact helical str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f946e97f802277d26614990bc47d7a
https://pubmed.ncbi.nlm.nih.gov/23487472
https://pubmed.ncbi.nlm.nih.gov/23487472
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38723 (2012)
PLoS ONE
PLoS ONE
Murine noroviruses have emerged as a valuable tool for investigating the molecular basis of infection and pathogenesis of the closely related human noroviruses, which are the major cause of non-bacterial gastroenteritis. The replication of noroviruse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5989a171fb6cf7dfe3ca67a69231b4b0
http://europepmc.org/articles/PMC3369882?pdf=render
http://europepmc.org/articles/PMC3369882?pdf=render