Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Eoin Coakley"'
Autor:
Liã Bárbara Arruda, Marilia Ladeira de Araújo, Maira Luccia Martinez, Claudio Roberto Gonsalez, Alberto José da Silva Duarte, Eoin Coakley, Yolanda Lie, Jorge Casseb
Publikováno v:
Revista do Instituto de Medicina Tropical de São Paulo, Vol 56, Iss 4, Pp 287-290 (2014)
The clinical application of CCR5 antagonists involves first determining the coreceptor usage by the infecting viral strain. Bioinformatics programs that predict coreceptor usage could provide an alternative method to screen candidates for treatment w
Externí odkaz:
https://doaj.org/article/3e31db1f605f49b08ea1b7ab1e4ca211
Autor:
Christian Pou, Francisco M Codoñer, Alexander Thielen, Rocío Bellido, Susana Pérez-Álvarez, Cecilia Cabrera, Judith Dalmau, Marta Curriu, Yolanda Lie, Marc Noguera-Julian, Jordi Puig, Javier Martínez-Picado, Julià Blanco, Eoin Coakley, Martin Däumer, Bonaventura Clotet, Roger Paredes
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e67085 (2013)
BACKGROUND: Technically, HIV-1 tropism can be evaluated in plasma or peripheral blood mononuclear cells (PBMCs). However, only tropism testing of plasma HIV-1 has been validated as a tool to predict virological response to CCR5 antagonists in clinica
Externí odkaz:
https://doaj.org/article/5168f5f2841948639ec02782a3c6235f
Autor:
Evelien M Bunnik, Luke C Swenson, Diana Edo-Matas, Wei Huang, Winnie Dong, Arne Frantzell, Christos J Petropoulos, Eoin Coakley, Hanneke Schuitemaker, P Richard Harrigan, Angélique B van 't Wout
Publikováno v:
PLoS Pathogens, Vol 7, Iss 6, p e1002106 (2011)
The emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants is associated with accelerated disease progression. CXCR4-using variants are believed to evolve from CCR5-using variants, but due to the extremely low frequency at whic
Externí odkaz:
https://doaj.org/article/ddfe04d332f1449b85173e4bb40d101d
Autor:
Agnes C Paquet, John Baxter, Jodi Weidler, Yolanda Lie, Jody Lawrence, Rose Kim, Michael Bates, Eoin Coakley, Colombe Chappey
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14638 (2011)
The CPCRA 064 study examined the effect of structured treatment interruption (STI) of up to 4 months followed by salvage treatment in patients failing therapy with multi-drug resistant HIV. We examined the relationship between the reversion rate of m
Externí odkaz:
https://doaj.org/article/d602fa8a08704a32a35e6afaf4a9f8c7
Autor:
Athe M N Tsibris, Bette Korber, Ramy Arnaout, Carsten Russ, Chien-Chi Lo, Thomas Leitner, Brian Gaschen, James Theiler, Roger Paredes, Zhaohui Su, Michael D Hughes, Roy M Gulick, Wayne Greaves, Eoin Coakley, Charles Flexner, Chad Nusbaum, Daniel R Kuritzkes
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5683 (2009)
High-throughput sequencing platforms provide an approach for detecting rare HIV-1 variants and documenting more fully quasispecies diversity. We applied this technology to the V3 loop-coding region of env in samples collected from 4 chronically HIV-i
Externí odkaz:
https://doaj.org/article/ed3bc53f5c7e4bbfbabd8a82f5be0776
Autor:
Monique Nijhuis, Noortje M van Maarseveen, Stephane Lastere, Pauline Schipper, Eoin Coakley, Bärbel Glass, Mirka Rovenska, Dorien de Jong, Colombe Chappey, Irma W Goedegebuure, Gabrielle Heilek-Snyder, Dominic Dulude, Nick Cammack, Lea Brakier-Gingras, Jan Konvalinka, Neil Parkin, Hans-Georg Kräusslich, Francoise Brun-Vezinet, Charles A B Boucher
Publikováno v:
PLoS Medicine, Vol 4, Iss 1, p e36 (2007)
BACKGROUND: HIV protease inhibitor (PI) therapy results in the rapid selection of drug resistant viral variants harbouring one or two substitutions in the viral protease. To combat PI resistance development, two approaches have been developed. The fi
Externí odkaz:
https://doaj.org/article/9b249d2a4df84827a9f40807268dca47
Autor:
K. Lin, Kajal B. Larson, Nathalie Adda, Nicolas Noulin, K. Kursten Tenhoor, A. Ahmad, Eoin Coakley, T. McClure
Publikováno v:
D16. INSIGHTS FROM CLINICAL STUDIES AND DATABASES IN PNEUMONIA.
Finite element analysis of the flexural behaviour of steel-reinforced GEM-TECH cementitious material
Publikováno v:
Engineering Solid Mechanics. :263-274
Autor:
Dali Bondar, Eoin Coakley
Publikováno v:
Bondar, D & Coakley, E 2017, ' Effect of grinding on early age performance of high volume fly ash ternary blended pastes with CKD & OPC ', Construction and Building Materials, vol. 136, pp. 153-163 . https://doi.org/10.1016/j.conbuildmat.2017.01.044
This study investigated setting times and early age compressive strength of the high volume fly ash (HVFA) blended pastes prepared with ground materials. The pastes consisted of 60% Fly Ash + 30% Portland cement (CEM I) + 10% cement kiln dust (CKD) a
Autor:
Yoninah S Cramer, Victoria A. Johnson, Michael S. Saag, Beatrice Kallungal, Edward P. Acosta, Eoin Coakley, Stephen Becker, Gary Calandra, Karin L. Klingman, Susan L. Rosenkranz
Publikováno v:
AIDS Res Hum Retroviruses
AMD11070 binds to the chemokine receptor CXCR4, with anti-HIV-1 activity in vitro and in vivo. We conducted a phase IB/IIA proof-of-concept dose-escalating, open-label study to determine safety and antiviral activity of AMD11070 administered over 10