Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eoin, Kelleher"'
Autor:
Amy P Worrall, Claire Kelly, Aine O'Neill, Murray O'Doherty, Eoin Kelleher, Anne Marie Cushen, Cora McNally, Samuel McConkey, Siobhan Glavey, Michelle Lavin, Eoghan de Barra
Publikováno v:
JMIR Formative Research, Vol 5, Iss 8, p e21817 (2021)
BackgroundEarly evidence of COVID-19–associated coagulopathy disseminated rapidly online during the first months of 2020, followed by clinical debate about how best to manage thrombotic risks in these patients. The rapid online spread of case repor
Externí odkaz:
https://doaj.org/article/8d4772766e0149a189eed5d852c02e2e
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Following the introduction of fully endoscopic techniques for the resection of pituitary tumors, there was a rapid expansion of the indications for endonasal endoscopic surgery to include extrasellar tumors of the skull base. These techniques offer s
Externí odkaz:
https://doaj.org/article/32f0f5f5fb6046c2b1230162ec57f8d8
Autor:
Joshua D, Thomas, Aleksandr V, Yurkovetskiy, Mao, Yin, Natalya D, Bodyak, Dmitry R, Gumerov, Shuyi, Tang, Eoin, Kelleher, Brian D, Jones, Marina, Protopopova, LiuLiang, Qin, Alex, Uttard, Damon R, Demady, Timothy B, Lowinger
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 72:128876
Pyrrolobenzodiazepine (PBD) dimers are well-known highly potent antibody drug conjugate (ADC) payloads. The corresponding PBD monomers, in contrast, have received much less attention from the ADC community. We prepared several novel polyamide-linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c28732d20f05570a4c9c7504b2fae53
https://doi.org/10.1016/j.bmcl.2022.128876
https://doi.org/10.1016/j.bmcl.2022.128876
Autor:
Naniye Malli Cetinbas, Kalli C. Catcott, Travis Monnell, Jahna Soomer-James, Keith Bentley, Susan Clardy, Bingfan Du, Eoin Kelleher, Marina Protopopova, Cheri Stevenson, Joshua D. Thomas, Alex Uttard, Dorin Toader, Jeremy Duvall, Raghida Bukhalid, Marc Damelin, Timothy B. Lowinger
Publikováno v:
Cancer Research. 82:2114-2114
STING pathway agonism has emerged as a potential therapeutic strategy to stimulate anti-tumor immune responses. We have previously shown that tumor cell-targeted antibody-drug conjugates (ADCs) carrying a novel STING agonist induce anti-tumor activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c61ff92e4fb7c9e4739a253221532097
https://doi.org/10.1158/1538-7445.am2022-2114
https://doi.org/10.1158/1538-7445.am2022-2114
Publikováno v:
Rheumatology. 60
Background/Aims Population-based studies suggest an association between pain in elderly adults and cognitive impairment. However, the temporal relationship between chronic pain and cognitive decline is uncertain: most studies are cross-sectional or h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15dbba00ea33ce8411acf88104f3316a
https://doi.org/10.1093/rheumatology/keab247.120
https://doi.org/10.1093/rheumatology/keab247.120
Chronic kidney disease (CKD) is strongly associated with the full spectrum of cerebrovascular disease including ischaemic and haemorrhagic stroke, small vessel disease, and vascular cognitive impairment. Shared conventional vascular risk factors such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b40a0ab91e49eb26317ddc5b1a2e9721
https://doi.org/10.1159/000517698
https://doi.org/10.1159/000517698
Autor:
Amy P Worrall, Claire Kelly, Aine O'Neill, Murray O'Doherty, Eoin Kelleher, Anne Marie Cushen, Cora McNally, Samuel McConkey, Siobhan Glavey, Michelle Lavin, Eoghan de Barra
BACKGROUND Early evidence of COVID-19–associated coagulopathy disseminated rapidly online during the first months of 2020, followed by clinical debate about how best to manage thrombotic risks in these patients. The rapid online spread of case repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bf470e2d284ea1ffe410cf12faf9cd0
https://doi.org/10.2196/preprints.21817
https://doi.org/10.2196/preprints.21817
Autor:
Murray O'Doherty, Michelle Lavin, Anne Marie Cushen, Samuel J. McConkey, Aine O'Neill, Eoghan de Barra, Siobhan Glavey, Cora McNally, Amy P Worrall, Eoin Kelleher, Claire Kelly
Publikováno v:
JMIR Formative Research
Background Early evidence of COVID-19–associated coagulopathy disseminated rapidly online during the first months of 2020, followed by clinical debate about how best to manage thrombotic risks in these patients. The rapid online spread of case repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3137b1ace507326c43c6ecee38c861a6
https://pubmed.ncbi.nlm.nih.gov/34292865
https://pubmed.ncbi.nlm.nih.gov/34292865
Autor:
Naniye Malli Cetinbas, Pamela Shaw, Dorin Toader, Keith W. Bentley, Eoin Kelleher, Susan M. Clardy, Marc Damelin, Jeremy R. Duvall, Rebecca Mosher, Winnie Lee, Brian D. Jones, Kenneth Avocetien, Travis Monnell, Kelly Slocum, Raghida A. Bukhalid, Joshua D. Thomas, Timothy B. Lowinger, Kalli C. Catcott
Publikováno v:
Cancer Research. 81:1773-1773
STING pathway plays a critical role in inducing anti-tumor immunity by upregulating Type 1 Interferon (IFN) and IFN-stimulated genes within the tumor microenvironment in response to cytosolic nucleic acid ligands. Therefore, the STING pathway agonism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9908c2e672c4e4b79e304926c0b68f5d
https://doi.org/10.1158/1538-7445.am2021-1773
https://doi.org/10.1158/1538-7445.am2021-1773