Zobrazeno 1 - 10 of 113 pro vyhledávání: '"Enzo Paoletti"'
1
Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization
Autor: Adrian V. S. Hill, Sarah C. Gilbert, Steve Harris, G. Frankel, Catherine E. M. Allsopp, Enzo Paoletti, Catarina E. Hioe, Robert E. Sinden, Douglas F. Nixon, Guy T. Layton, Magdalena Plebanski, Gordon Dougan
Publikováno v: Scopus-Elsevier
A variety of vaccine delivery systems including peptides with various adjuvants, recombinant particles, live recombinant viruses and bacteria and plasmid DNA were tested for their ability to induce CD8+ cytotoxic T lymphocytes (CTL) against a well-de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf765fcd4c8b2db3192965b67b0bbab7
https://ora.ox.ac.uk/objects/uuid:9a04b05f-412e-416f-8326-9886f36f90a7
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2
Role of the Vaccinia Virus E3L and K3L Gene Products in Rescue of VSV and EMCV from the Effects of IFN-α
Autor: Elizabeth Beattie, Scott T. Shors, Bertram L. Jacobs, James Tartaglia, Enzo Paoletti
Publikováno v: Journal of Interferon & Cytokine Research. 18:721-729
Vaccinia virus (VV) has been shown to be relatively resistant to the antiviral effects of interferon-alpha (IFN-alpha) and to rescue replication of IFN-sensitive viruses, such as encephalomyocarditis virus (EMCV) and vesicular stomatitis virus (VSV),
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dea63fce0200c660022bd80ed2d6a1
https://doi.org/10.1089/jir.1998.18.721
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4
Replication-Defective Canarypox (ALVAC) Vectors Effectively Activate Anti–Human Immunodeficiency Virus-1 Cytotoxic T Lymphocytes Present in Infected Patients: Implications for Antigen-Specific Immunotherapy
Autor: Jim Tartaglia, Guido Ferrari, Kent J. Weinhold, C. Berend, D. Moody, W.I. Cox, John Bartlett, J. F. Toso, Janet Ottinger, R. Dodge, Enzo Paoletti
Publikováno v: Scopus-Elsevier
In the attempt to develop immunotherapeutic strategies for acquired immunodeficiency syndrome capable of activating effector cells in an antigen-specific manner while maintaining the broadest possible T-cell repertoire, we evaluated two canarypox (AL
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922fff45ca64b662682d784e26c37dcc
https://doi.org/10.1182/blood.v90.6.2406
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5
Memory Cytotoxic T Lymphocyte Responses in Human Immunodeficiency Virus Type 1 (HIV-1)-Negative Volunteers Immunized with a Recombinant Canarypox Expressing gp160 of HIV-1 and Boosted with a Recombinant gp160
Autor: Enzo Paoletti, Yves Rivière, Florence Buseyne, Marie Paule Kieny, Gilles Pialoux, Michael N. Robertson, Béatrice Fleury, James Tartaglia, Geneviève Janvier, Jean Louis Excler
Publikováno v: Journal of Infectious Diseases. 174:734-738
A vaccine against human immunodeficiency virus (HIV) should induce virus-specific cytotoxic T lymphocyte (CTL) activity. Immunization of uninfected volunteers with a canarypox virus express­ ing HIV envelope was carried out in a phase I trial. Two i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdc521afeec6afe5b1257679e2f23ef
https://doi.org/10.1093/infdis/174.4.734
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6
NYVAC-Pf7: a poxvirus-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria
Autor: G. S. N. Hui, Lisa A. Ware, C. De Taisne, David C. Kaslow, David E. Lanar, W. R. Ballou, Stephen L. Hoffman, E. B. Kauffman, John A. Tine, Jerald C. Sadoff, Bruce T. Wellde, Robert A. Wirtz, S. P. Chang, D. M. Smith, Enzo Paoletti, K. P. Guito, P. Church, P. Schultheiss, Michael R. Hollingdale
Publikováno v: Infection and Immunity. 64:3833-3844
The highly attenuated NYVAC vaccinia virus strain has been utilized to develop a multiantigen, multistage vaccine candidate for malaria, a disease that remains a serious global health problem and for which no highly effective vaccine exists. Genes en
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90ba88a2f73d41d05fc371748a7451f
https://doi.org/10.1128/iai.64.9.3833-3844.1996
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7
Multiple Immunizations with Attenuated Poxvirus HIV Type 2 Recombinants and Subunit Boosts Required for Protection of Rhesus Macaques
Autor: Enzo Paoletti, Maria Myagkikh, Marjorie Robert-Guroff, Shabnam Alipanah, Genoveffa Franchini, Phillip D. Markham, Robert C. Gallo, James Tartaglia
Publikováno v: AIDS Research and Human Retroviruses. 12:985-992
Vaccine protocols involving multiple immunizations with molecularly attenuated vaccinia virus (NYVAC) or naturally attenuated canarypox virus (ALVAC) HIV-2 recombinants and subunit boosts have conferred longlasting protection against HIV-2 infection
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87efdea92a9ffb3babbb4f882ae3d93
https://doi.org/10.1089/aid.1996.12.985
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8
p53 as a target for cancer vaccines: recombinant canarypox virus vectors expressing p53 protect mice against lethal tumor cell challenge
Autor: Arnold J. Levine, Enzo Paoletti, Judith Roth, Dirk P. Dittmer, James Tartaglia, Delphine Rea
Publikováno v: Europe PubMed Central
The p53 protein is an attractive target for immunotherapy, because mutations in the p53 gene are the most common genetic alterations found in human tumors. These mutations result in high levels of p53 protein in the tumor cell, whereas the expression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1982a5320d534b5a92b06a15487db53e
https://doi.org/10.1073/pnas.93.10.4781
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9
Attenuated vaccinia virus-circumsporozoite protein recombinants confer protection against rodent malaria
Autor: M C Seguin, E. B. Kauffman, W.I. Cox, C. De Taisne, Daniel M. Gordon, Jerald C. Sadoff, Enzo Paoletti, John A. Tine, J P Winslow, Lisa A. Ware, W. R. Ballou, David E. Lanar
Publikováno v: Infection and Immunity. 64:1666-1671
NYVAC-based vaccinia virus recombinants expressing the circumsporozoite protein (CSP) were evaluated in the Plasmodium berghei rodent malaria model system. Immunization of mice with a NYVAC-based CSP recombinant elicited a high level of protection (6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8426ad4130e5b84bbdc77d2d141bcb9
https://doi.org/10.1128/iai.64.5.1666-1671.1996
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10
Human safety and immunogenicity of a canarypox-rabies glycoprotein recombinant vaccine: an alternative poxvirus vector system
Autor: Bernard Meignier, Jill Taylor, E.K. Kauffman, Stanley A. Plotkin, James Tartaglia, Enzo Paoletti, Louis Fries
Publikováno v: Vaccine. 14:428-434
Avian poxvirus recombinants undergo abortive replication in nonavian cells, yet can achieve expression of extrinsic gene products. Canarypox-vectored vaccines have been innocuous and immunogenic in several mammalian species. ALVAC-RG, a canarypox rec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e474cba5513db79e08be066185301e
https://doi.org/10.1016/0264-410x(95)00171-v
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